PF00389


Help to interpret the results

Three outputs have been generated:
General: this result contains the description and frequency of the selected Pfam domains PF00389, of which KO pathways and KO modules it is part. Additionally, its occurence in the database is reported.
Proteins list: list of occurences of the Pfam domains within the database. 28 occurences are identified. The table reports the orthogroup, the organism in which each occurrence has been found, and the locus tag enriched by start and stop position, strand, gene name and product.
Clicking on the Ortohgroup name or locus you will be redirected to further info.
Profiles: Phylogenetic tree annotated with
- the presence of the Pfam domain(s) of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported Pfam domains has been clustered.
In red the Pfam domains with positive hit(s) in the corresponding genome.
In green the discrepencies between orthogroup clustering and Pfam domains prediction. Green homologs (same orthogroup) are not positive hit(s) for the considered Pfam domains.

Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or Pfam domains prediction.

Description

External link PF00389
Description D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain

Occurence in the database

PF00389 is associated with 28 different proteins (see tab "Protein list" and "Profile")
The 28 proteins are classified into 4 different orthogroup(s)
# Orthogroup Locus Start Stop S. Gene Product Organism
0 group_660 FBDBKF_02340 157368 158369 -1 ldhA Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase Morganella morganii S1
1 group_831 FBDBKF_04180 21061 22311 -1 serA phosphoglycerate dehydrogenase Morganella morganii S1
2 group_1657 FBDBKF_11020 24801 25778 -1 ghrB glyoxylate/hydroxypyruvate reductase GhrB Morganella morganii S1
3 group_1918 FBDBKF_14275 54315 55460 -1 pdxB 4-phosphoerythronate dehydrogenase PdxB Morganella morganii S1
4 group_660 EHELCC_02810 545188 546189 -1 ldhA Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase Morganella morganii S2
5 group_1657 EHELCC_05205 33690 34667 1 ghrB glyoxylate/hydroxypyruvate reductase GhrB Morganella morganii S2
6 group_831 EHELCC_05470 80518 81768 -1 serA phosphoglycerate dehydrogenase Morganella morganii S2
7 group_1918 EHELCC_08005 61525 62670 1 pdxB 4-phosphoerythronate dehydrogenase PdxB Morganella morganii S2
8 group_660 NLDBIP_00650 133947 134948 1 ldhA Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase Morganella morganii S4
9 group_1657 NLDBIP_05525 74755 75732 1 ghrB glyoxylate/hydroxypyruvate reductase GhrB Morganella morganii S4
10 group_831 NLDBIP_05790 121583 122833 -1 serA phosphoglycerate dehydrogenase Morganella morganii S4
11 group_1918 NLDBIP_08330 61525 62670 1 pdxB 4-phosphoerythronate dehydrogenase PdxB Morganella morganii S4
12 group_660 LHKJJB_01385 257737 258738 -1 ldhA Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase Morganella morganii S3
13 group_1657 LHKJJB_02405 52279 53256 1 ghrB glyoxylate/hydroxypyruvate reductase GhrB Morganella morganii S3
14 group_831 LHKJJB_02670 99107 100357 -1 serA phosphoglycerate dehydrogenase Morganella morganii S3
15 group_1918 LHKJJB_05935 194489 195634 -1 pdxB 4-phosphoerythronate dehydrogenase PdxB Morganella morganii S3
16 group_660 HKOGLL_01425 263248 264249 -1 ldhA Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase Morganella morganii S5
17 group_1918 HKOGLL_04980 46116 47261 1 pdxB 4-phosphoerythronate dehydrogenase PdxB Morganella morganii S5
18 group_831 HKOGLL_06145 20971 22221 -1 serA phosphoglycerate dehydrogenase Morganella morganii S5
19 group_1657 HKOGLL_15785 75719 76696 1 ghrB glyoxylate/hydroxypyruvate reductase GhrB Morganella morganii S5
20 group_1918 F4V73_RS02635 555045 556175 1 pdxB 4-phosphoerythronate dehydrogenase PdxB Morganella psychrotolerans
21 group_660 F4V73_RS04720 996006 997010 -1 2-hydroxyacid dehydrogenase Morganella psychrotolerans
22 group_1657 F4V73_RS08210 1707762 1708739 1 ghrB glyoxylate/hydroxypyruvate reductase GhrB Morganella psychrotolerans
23 group_831 F4V73_RS08625 1780485 1781735 -1 serA phosphoglycerate dehydrogenase Morganella psychrotolerans
24 group_660 PMI_RS05700 1241347 1242345 -1 2-hydroxyacid dehydrogenase Proteus mirabilis HI4320
25 group_1918 PMI_RS08785 1920895 1922022 -1 pdxB 4-phosphoerythronate dehydrogenase PdxB Proteus mirabilis HI4320
26 group_1657 PMI_RS09620 2101949 2102908 1 ghrB glyoxylate/hydroxypyruvate reductase GhrB Proteus mirabilis HI4320
27 group_831 PMI_RS10015 2173709 2174959 -1 serA phosphoglycerate dehydrogenase Proteus mirabilis HI4320