PF00180


Help to interpret the results

Three outputs have been generated:
General: this result contains the description and frequency of the selected Pfam domains PF00180, of which KO pathways and KO modules it is part. Additionally, its occurence in the database is reported.
Proteins list: list of occurences of the Pfam domains within the database. 14 occurences are identified. The table reports the orthogroup, the organism in which each occurrence has been found, and the locus tag enriched by start and stop position, strand, gene name and product.
Clicking on the Ortohgroup name or locus you will be redirected to further info.
Profiles: Phylogenetic tree annotated with
- the presence of the Pfam domain(s) of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported Pfam domains has been clustered.
In red the Pfam domains with positive hit(s) in the corresponding genome.
In green the discrepencies between orthogroup clustering and Pfam domains prediction. Green homologs (same orthogroup) are not positive hit(s) for the considered Pfam domains.

Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or Pfam domains prediction.

Description

External link PF00180
Description Isocitrate/isopropylmalate dehydrogenase

Occurence in the database

PF00180 is associated with 14 different proteins (see tab "Protein list" and "Profile")
The 14 proteins are classified into 2 different orthogroup(s)
# Orthogroup Locus Start Stop S. Gene Product Organism
0 group_870 FBDBKF_04415 76270 77361 1 leuB 3-isopropylmalate dehydrogenase Morganella morganii S1
1 group_1937 FBDBKF_14545 3630 4883 -1 icd NADP-dependent isocitrate dehydrogenase Morganella morganii S1
2 group_870 EHELCC_05705 135727 136818 1 leuB 3-isopropylmalate dehydrogenase Morganella morganii S2
3 group_1937 EHELCC_15350 33706 34959 -1 icd NADP-dependent isocitrate dehydrogenase Morganella morganii S2
4 group_870 NLDBIP_06025 176792 177883 1 leuB 3-isopropylmalate dehydrogenase Morganella morganii S4
5 group_1937 NLDBIP_15880 33706 34959 -1 icd NADP-dependent isocitrate dehydrogenase Morganella morganii S4
6 group_870 LHKJJB_02905 154316 155407 1 leuB 3-isopropylmalate dehydrogenase Morganella morganii S3
7 group_1937 LHKJJB_15960 81727 82980 1 icd NADP-dependent isocitrate dehydrogenase Morganella morganii S3
8 group_870 HKOGLL_06380 76180 77271 1 leuB 3-isopropylmalate dehydrogenase Morganella morganii S5
9 group_1937 HKOGLL_15080 80939 82192 1 icd NADP-dependent isocitrate dehydrogenase Morganella morganii S5
10 group_1937 F4V73_RS07340 1531909 1533162 -1 icd NADP-dependent isocitrate dehydrogenase Morganella psychrotolerans
11 group_870 F4V73_RS08860 1837377 1838492 1 leuB 3-isopropylmalate dehydrogenase Morganella psychrotolerans
12 group_1937 PMI_RS04380 982975 984228 1 icd NADP-dependent isocitrate dehydrogenase Proteus mirabilis HI4320
13 group_870 PMI_RS10270 2251961 2253052 1 leuB 3-isopropylmalate dehydrogenase Proteus mirabilis HI4320