K00135


Help to interpret the results

Three outputs have been generated:
General: this tab contains the description, occurence in the database and other information related to the selected Kegg Ortholog K00135
Protein list: lists the 7 occurences of the Kegg Ortholog within the database. The table reports information on each occurence.
Profile: phylogenetic tree annotated with
- the presence of the Kegg Ortholog of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported Kegg Ortholog has been clustered.
Orthogroups are shown in red if they are annotated with that particular Kegg Ortholog in a given genome , in green otherwise, i.e. if there is a discrepency between orthogroup clustering and Kegg Ortholog prediction.
Green homologs (same orthogroup) are not positive hit(s) for the considered Kegg Ortholog.
Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or Kegg Ortholog prediction.

Description

External link K00135
KO K00135
Description succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]

KO part of 7 pathways

Alanine, aspartate and glutamate metabolism
Lysine degradation
Tyrosine metabolism
Butanoate metabolism
Nicotinate and nicotinamide metabolism
Metabolic pathways
Microbial metabolism in diverse environments

KO part of 3 modules

M00027 Other amino acid metabolism GABA (gamma-Aminobutyrate) shunt
M00956 Lysine metabolism Lysine degradation, bacteria, L-lysine => succinate
M00957 Lysine metabolism Lysine degradation, bacteria, L-lysine => glutarate => succinate/acetyl-CoA

Occurence in the database

K00135 is associated with 7 different proteins
The 7 proteins are classified into 1 different orthogroup(s)
Orthogroup Locus Start Stop S. Gene Product Organism
0 group_1886 FBDBKF_13820 57272 58744 1 gabD Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase Morganella morganii S1
1 group_1886 EHELCC_11490 142148 143620 1 gabD Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase Morganella morganii S2
2 group_1886 NLDBIP_11835 142148 143620 1 gabD Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase Morganella morganii S4
3 group_1886 LHKJJB_11695 142148 143620 1 gabD Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase Morganella morganii S3
4 group_1886 HKOGLL_10305 142148 143620 1 gabD Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase Morganella morganii S5
5 group_1886 F4V73_RS12685 135749 137221 1 NAD-dependent succinate-semialdehyde dehydrogenase Morganella psychrotolerans
6 group_1886 PMI_RS16840 3708297 3709745 -1 NAD-dependent succinate-semialdehyde dehydrogenase Proteus mirabilis HI4320