dfrA12


Help to interpret the results

Three outputs have been generated:
General: this result contains the description and frequency of the selected AMR genes dfrA12, of which KO pathways and KO modules it is part. Additionally, its occurence in the database is reported.
Proteins list: list of occurences of the AMR genes within the database. 4 occurences are identified. The table reports the orthogroup, the organism in which each occurrence has been found, and the locus tag enriched by start and stop position, strand, gene name and product.
Clicking on the Ortohgroup name or locus you will be redirected to further info.
Profiles: Phylogenetic tree annotated with
- the presence of the AMR gene(s) of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported AMR genes has been clustered.
In red the AMR genes with positive hit(s) in the corresponding genome.
In green the discrepencies between orthogroup clustering and AMR genes prediction. Green homologs (same orthogroup) are not positive hit(s) for the considered AMR genes.

Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or AMR genes prediction.

Description

Gene dfrA12
Description trimethoprim-resistant dihydrofolate reductase DfrA12
Scope core
Type AMR
Class TRIMETHOPRIM
Subclass TRIMETHOPRIM
HMM NF000053 

Occurence in the database

dfrA12 is associated with 4 different proteins (see tab "Protein list" and "Profile")
The 4 proteins are classified into 1 different orthogroup(s)
# Orthogroup Locus Start Stop S. Gene Product Organism
0 group_3671 FBDBKF_20545 1833 2330 -1 dfrA12 trimethoprim-resistant dihydrofolate reductase DfrA12 Morganella morganii S1
1 group_3671 NLDBIP_19860 155 652 1 dfrA12 trimethoprim-resistant dihydrofolate reductase DfrA12 Morganella morganii S4
2 group_3671 LHKJJB_19825 387 884 1 dfrA12 trimethoprim-resistant dihydrofolate reductase DfrA12 Morganella morganii S3
3 group_3671 HKOGLL_19695 1833 2330 -1 dfrA12 trimethoprim-resistant dihydrofolate reductase DfrA12 Morganella morganii S5