Help to interpret the results
The page contains two contents:
General: this table lists the KO entries and their description specific to this pathway, and provides their frequencies in Morganella morganii S5 and in the whole dataset.
Profile + homologs: the distribution of the Kegg entries of Hepatocellular carcinoma Kegg pathway is displayed here. Given a Kegg entry and a genome, a red box indicates that one or more loci have been annotated with, while a green box indicates that no locus/loci has(have) been annotated with it, but it/they is/are part of an Orthologous group in which other members have been annotated with that Kegg entry, so it is likely that this copy(ies) also performs this Kegg function.
Check the composition of the Hepatocellular carcinoma pathway
| KO | Description | #in this genome | All occurrences |
|---|---|---|---|
| K00182 | wingless-type MMTV integration site family, member 2 | 0 | 0 |
| K00312 | wingless-type MMTV integration site family, member 3 | 0 | 0 |
| K00355 | NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2] | 0 | 0 |
| K00408 | wingless-type MMTV integration site family, member 4 | 0 | 0 |
| K00444 | wingless-type MMTV integration site family, member 5 | 0 | 0 |
| K00445 | wingless-type MMTV integration site family, member 6 | 0 | 0 |
| K00510 | heme oxygenase 1 [EC:1.14.14.18] | 0 | 0 |
| K00572 | wingless-type MMTV integration site family, member 7 | 0 | 0 |
| K00714 | wingless-type MMTV integration site family, member 8 | 0 | 0 |
| K00799 | glutathione S-transferase [EC:2.5.1.18] | 5 | 31 |
| K00922 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153] | 0 | 0 |
| K01064 | wingless-type MMTV integration site family, member 9 | 0 | 0 |
| K01110 | phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67] | 0 | 0 |
| K01116 | phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11] | 0 | 0 |
| K01357 | wingless-type MMTV integration site family, member 10 | 0 | 0 |
| K01384 | wingless-type MMTV integration site family, member 11 | 0 | 0 |
| K01558 | wingless-type MMTV integration site family, member 16 | 0 | 0 |
| K02085 | adenomatosis polyposis coli protein | 0 | 0 |
| K02089 | cyclin-dependent kinase 4 [EC:2.7.11.22] | 0 | 0 |
| K02091 | cyclin-dependent kinase 6 [EC:2.7.11.22] | 0 | 0 |
| K02105 | catenin beta 1 | 0 | 0 |
| K02157 | axin 1 | 0 | 0 |
| K02158 | Bcl-2-antagonist of cell death | 0 | 0 |
| K02159 | apoptosis regulator BAX | 0 | 0 |
| K02235 | frizzled 2 | 0 | 0 |
| K02329 | frizzled 3 | 0 | 0 |
| K02353 | segment polarity protein dishevelled | 0 | 0 |
| K02354 | frizzled 4 | 0 | 0 |
| K02375 | frizzled 5/8 | 0 | 0 |
| K02376 | frizzled 6 | 0 | 0 |
| K02432 | frizzled 1/7 | 0 | 0 |
| K02620 | transcription factor 7 | 0 | 0 |
| K02649 | phosphoinositide-3-kinase regulatory subunit alpha/beta/delta | 0 | 0 |
| K02677 | classical protein kinase C alpha type [EC:2.7.11.13] | 0 | 0 |
| K02833 | GTPase HRas | 0 | 0 |
| K02842 | frizzled 9/10 | 0 | 0 |
| K03068 | low density lipoprotein receptor-related protein 5/6 | 0 | 0 |
| K03069 | frequently rearranged in advanced T-cell lymphomas 1 | 0 | 0 |
| K03083 | glycogen synthase kinase 3 beta [EC:2.7.11.26] | 0 | 0 |
| K03096 | frequently rearranged in advanced T-cell lymphomas 2 | 0 | 0 |
| K03099 | son of sevenless | 0 | 0 |
| K03209 | wingless-type MMTV integration site family, member 1 | 0 | 0 |
| K03511 | DNA polymerase kappa [EC:2.7.7.7] | 0 | 0 |
| K04361 | epidermal growth factor receptor [EC:2.7.10.1] | 0 | 0 |
| K04364 | growth factor receptor-bound protein 2 | 0 | 0 |
| K04365 | B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1] | 0 | 0 |
| K04366 | RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1] | 0 | 0 |
| K04368 | mitogen-activated protein kinase kinase 1 [EC:2.7.12.2] | 0 | 0 |
| K04369 | mitogen-activated protein kinase kinase 2 [EC:2.7.12.2] | 0 | 0 |
| K04371 | mitogen-activated protein kinase 1/3 [EC:2.7.11.24] | 0 | 0 |
| K04375 | ETS domain-containing protein Elk-1 | 0 | 0 |
| K04377 | Myc proto-oncogene protein | 0 | 0 |
| K04385 | axin 2 | 0 | 0 |
| K04388 | TGF-beta receptor type-2 [EC:2.7.11.30] | 0 | 0 |
| K04402 | growth arrest and DNA-damage-inducible protein | 0 | 0 |
| K04451 | tumor protein p53 | 0 | 0 |
| K04456 | RAC serine/threonine-protein kinase [EC:2.7.11.1] | 0 | 0 |
| K04490 | transcription factor 7-like 1 | 0 | 0 |
| K04491 | transcription factor 7-like 2 | 0 | 0 |
| K04492 | lymphoid enhancer-binding factor 1 | 0 | 0 |
| K04500 | mothers against decapentaplegic homolog 2 | 0 | 0 |
| K04501 | mothers against decapentaplegic homolog 4 | 0 | 0 |
| K04503 | G1/S-specific cyclin-D1 | 0 | 0 |
| K04570 | Bcl-2-like 1 (apoptosis regulator Bcl-X) | 0 | 0 |
| K04674 | TGF-beta receptor type-1 [EC:2.7.11.30] | 0 | 0 |
| K04688 | ribosomal protein S6 kinase beta [EC:2.7.11.1] | 0 | 0 |
| K05087 | insulin-like growth factor 1 receptor [EC:2.7.10.1] | 0 | 0 |
| K05099 | proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1] | 0 | 0 |
| K05460 | hepatocyte growth factor | 0 | 0 |
| K05638 | nuclear factor erythroid 2-related factor 2 | 0 | 0 |
| K05692 | actin beta/gamma 1 | 0 | 0 |
| K05859 | phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11] | 0 | 0 |
| K06279 | SHC-transforming protein 1 | 0 | 0 |
| K06618 | retinoblastoma-associated protein | 0 | 0 |
| K06620 | transcription factor E2F3 | 0 | 0 |
| K06621 | cyclin-dependent kinase inhibitor 2A | 0 | 0 |
| K06625 | cyclin-dependent kinase inhibitor 1A | 0 | 0 |
| K07203 | serine/threonine-protein kinase mTOR [EC:2.7.11.1] | 0 | 0 |
| K07827 | GTPase KRas | 0 | 0 |
| K07828 | GTPase NRas | 0 | 0 |
| K08774 | transforming growth factor, alpha | 0 | 0 |
| K08845 | A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1] | 0 | 0 |
| K08957 | casein kinase 1, alpha [EC:2.7.11.1] | 0 | 0 |
| K09389 | transcription factor E2F2 | 0 | 0 |
| K09593 | GRB2-associated-binding protein 1 | 0 | 0 |
| K10140 | DNA damage-binding protein 2 | 0 | 0 |
| K10456 | kelch-like protein 19 | 0 | 0 |
| K11126 | telomerase reverse transcriptase [EC:2.7.7.49] | 0 | 0 |
| K11340 | actin-like protein 6A | 0 | 0 |
| K11647 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:5.6.2.-] | 0 | 0 |
| K11648 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 | 0 | 0 |
| K11649 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C | 0 | 0 |
| K11650 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D | 0 | 0 |
| K11651 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 | 0 | 0 |
| K11652 | actin-like protein 6B | 0 | 0 |
| K11653 | AT-rich interactive domain-containing protein 1 | 0 | 0 |
| K11723 | bromodomain-containing protein 7 | 0 | 0 |
| K11757 | protein polybromo-1 | 0 | 0 |
| K11765 | AT-rich interactive domain-containing protein 2 | 0 | 0 |
| K13375 | transforming growth factor beta-1 | 0 | 0 |
| K13376 | transforming growth factor beta-2 | 0 | 0 |
| K13377 | transforming growth factor beta-3 | 0 | 0 |
| K13769 | insulin-like growth factor 2 | 0 | 0 |
| K14021 | Bcl-2 homologous antagonist/killer | 0 | 0 |
| K17447 | SHC-transforming protein 2 | 0 | 0 |
| K17448 | SHC-transforming protein 3 | 0 | 0 |
| K17449 | SHC-transforming protein 4 | 0 | 0 |
| K17454 | transcription factor E2F1 | 0 | 0 |
| K19662 | classical protein kinase C beta type [EC:2.7.11.13] | 0 | 0 |
| K19663 | classical protein kinase C gamma type [EC:2.7.11.13] | 0 | 0 |
| K22182 | thioredoxin reductase (NADPH) [EC:1.8.1.9] | 0 | 0 |
| K22183 | telomerase RNA component | 0 | 0 |
| K22197 | BRG1-associated factor 45A | 0 | 0 |
| K22198 | BRG1-associated factor 45B/C | 0 | 0 |
| K23605 | mothers against decapentaplegic homolog 3 | 0 | 0 |
| K23790 | glutathione S-transferase P [EC:2.5.1.18] | 0 | 0 |