Chemical carcinogenesis - receptor activation
Help to interpret the results
The page contains two contents:
General: this table lists the KO entries and their description specific to this pathway, and provides their frequencies in Proteus mirabilis HI4320 and in the whole dataset.
Profile + homologs: the distribution of the Kegg entries of Chemical carcinogenesis - receptor activation Kegg pathway is displayed here. Given a Kegg entry and a genome, a red box indicates that one or more loci have been annotated with, while a green box indicates that no locus/loci has(have) been annotated with it, but it/they is/are part of an Orthologous group in which other members have been annotated with that Kegg entry, so it is likely that this copy(ies) also performs this Kegg function.
Check the composition of the Chemical carcinogenesis - receptor activation pathway
| KO | Description | #in this genome | All occurrences |
|---|---|---|---|
| K00699 | glucuronosyltransferase [EC:2.4.1.17] | 0 | 0 |
| K00799 | glutathione S-transferase [EC:2.5.1.18] | 2 | 31 |
| K00922 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153] | 0 | 0 |
| K01253 | microsomal epoxide hydrolase [EC:3.3.2.9] | 0 | 0 |
| K02158 | Bcl-2-antagonist of cell death | 0 | 0 |
| K02161 | apoptosis regulator Bcl-2 | 0 | 0 |
| K02213 | cell division control protein 6 | 0 | 0 |
| K02580 | nuclear factor NF-kappa-B p105 subunit | 0 | 0 |
| K02649 | phosphoinositide-3-kinase regulatory subunit alpha/beta/delta | 0 | 0 |
| K02677 | classical protein kinase C alpha type [EC:2.7.11.13] | 0 | 0 |
| K02833 | GTPase HRas | 0 | 0 |
| K03099 | son of sevenless | 0 | 0 |
| K03209 | wingless-type MMTV integration site family, member 1 | 0 | 0 |
| K04079 | molecular chaperone HtpG | 1 | 7 |
| K04141 | adrenergic receptor beta-1 | 0 | 0 |
| K04142 | adrenergic receptor beta-2 | 0 | 0 |
| K04143 | adrenergic receptor beta-3 | 0 | 0 |
| K04344 | voltage-dependent calcium channel P/Q type alpha-1A | 0 | 0 |
| K04345 | protein kinase A [EC:2.7.11.11] | 0 | 0 |
| K04357 | epidermal growth factor | 0 | 0 |
| K04358 | fibroblast growth factor | 0 | 0 |
| K04361 | epidermal growth factor receptor [EC:2.7.10.1] | 0 | 0 |
| K04364 | growth factor receptor-bound protein 2 | 0 | 0 |
| K04366 | RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1] | 0 | 0 |
| K04368 | mitogen-activated protein kinase kinase 1 [EC:2.7.12.2] | 0 | 0 |
| K04369 | mitogen-activated protein kinase kinase 2 [EC:2.7.12.2] | 0 | 0 |
| K04371 | mitogen-activated protein kinase 1/3 [EC:2.7.11.24] | 0 | 0 |
| K04373 | ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1] | 0 | 0 |
| K04374 | cyclic AMP-dependent transcription factor ATF-4 | 0 | 0 |
| K04377 | Myc proto-oncogene protein | 0 | 0 |
| K04379 | proto-oncogene protein c-fos | 0 | 0 |
| K04439 | beta-arrestin | 0 | 0 |
| K04447 | Janus kinase 2 [EC:2.7.10.2] | 0 | 0 |
| K04448 | transcription factor AP-1 | 0 | 0 |
| K04450 | cyclic AMP-dependent transcription factor ATF-2 | 0 | 0 |
| K04456 | RAC serine/threonine-protein kinase [EC:2.7.11.1] | 0 | 0 |
| K04503 | G1/S-specific cyclin-D1 | 0 | 0 |
| K04630 | guanine nucleotide-binding protein G(i) subunit alpha | 0 | 0 |
| K04632 | guanine nucleotide-binding protein G(s) subunit alpha | 0 | 0 |
| K04688 | ribosomal protein S6 kinase beta [EC:2.7.11.1] | 0 | 0 |
| K04692 | signal transducer and activator of transcription 3 | 0 | 0 |
| K04725 | E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27] | 0 | 0 |
| K04735 | transcription factor p65 | 0 | 0 |
| K04805 | nicotinic acetylcholine receptor alpha-3 | 0 | 0 |
| K04806 | nicotinic acetylcholine receptor alpha-4 | 0 | 0 |
| K04809 | nicotinic acetylcholine receptor alpha-7 | 0 | 0 |
| K04810 | nicotinic acetylcholine receptor alpha-9 | 0 | 0 |
| K04813 | nicotinic acetylcholine receptor beta-2 | 0 | 0 |
| K04815 | nicotinic acetylcholine receptor beta-4 | 0 | 0 |
| K04849 | voltage-dependent calcium channel N type alpha-1B | 0 | 0 |
| K04850 | voltage-dependent calcium channel L type alpha-1C | 0 | 0 |
| K04851 | voltage-dependent calcium channel L type alpha-1D | 0 | 0 |
| K04853 | voltage-dependent calcium channel L type alpha-1F | 0 | 0 |
| K04857 | voltage-dependent calcium channel L type alpha-1S | 0 | 0 |
| K05448 | vascular endothelial growth factor A | 0 | 0 |
| K05473 | tumor necrosis factor ligand superfamily member 11 | 0 | 0 |
| K05704 | tyrosine-protein kinase Src [EC:2.7.10.2] | 0 | 0 |
| K05870 | cyclic AMP-responsive element-binding protein 1 | 0 | 0 |
| K06051 | delta | 0 | 0 |
| K06052 | jagged-1 | 0 | 0 |
| K06618 | retinoblastoma-associated protein | 0 | 0 |
| K06645 | M-phase inducer phosphatase 1 [EC:3.1.3.48] | 0 | 0 |
| K07203 | serine/threonine-protein kinase mTOR [EC:2.7.11.1] | 0 | 0 |
| K07205 | eukaryotic translation initiation factor 4E binding protein 1 | 0 | 0 |
| K07211 | inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10] | 0 | 0 |
| K07294 | peroxisome proliferator-activated receptor alpha | 0 | 0 |
| K07408 | cytochrome P450 family 1 subfamily A1 [EC:1.14.14.1] | 0 | 0 |
| K07409 | cytochrome P450 family 1 subfamily A2 [EC:1.14.14.1] | 0 | 0 |
| K07410 | cytochrome P450 family 1 subfamily B1 [EC:1.14.14.1] | 0 | 0 |
| K07412 | cytochrome P450 family 2 subfamily B [EC:1.14.14.1] | 0 | 0 |
| K07424 | cytochrome P450 family 3 subfamily A [EC:1.14.14.1] | 0 | 0 |
| K07827 | GTPase KRas | 0 | 0 |
| K07828 | GTPase NRas | 0 | 0 |
| K08041 | adenylate cyclase 1 [EC:4.6.1.1] | 0 | 0 |
| K08042 | adenylate cyclase 2 [EC:4.6.1.1] | 0 | 0 |
| K08043 | adenylate cyclase 3 [EC:4.6.1.1] | 0 | 0 |
| K08044 | adenylate cyclase 4 [EC:4.6.1.1] | 0 | 0 |
| K08045 | adenylate cyclase 5 [EC:4.6.1.1] | 0 | 0 |
| K08046 | adenylate cyclase 6 [EC:4.6.1.1] | 0 | 0 |
| K08047 | adenylate cyclase 7 [EC:4.6.1.1] | 0 | 0 |
| K08048 | adenylate cyclase 8 [EC:4.6.1.1] | 0 | 0 |
| K08049 | adenylate cyclase 9 [EC:4.6.1.1] | 0 | 0 |
| K08524 | retinoid X receptor alpha | 0 | 0 |
| K08525 | retinoid X receptor beta | 0 | 0 |
| K08526 | retinoid X receptor gamma | 0 | 0 |
| K08539 | vitamin D3 receptor | 0 | 0 |
| K08541 | constitutive androstane receptor | 0 | 0 |
| K08550 | estrogen receptor alpha | 0 | 0 |
| K08551 | estrogen receptor beta | 0 | 0 |
| K08556 | progesterone receptor | 0 | 0 |
| K08557 | androgen receptor | 0 | 0 |
| K08726 | soluble epoxide hydrolase / lipid-phosphate phosphatase [EC:3.3.2.10 3.1.3.76] | 0 | 0 |
| K08731 | baculoviral IAP repeat-containing protein 5 | 0 | 0 |
| K09047 | cyclic AMP-responsive element-binding protein 5 | 0 | 0 |
| K09048 | cyclic AMP-responsive element-binding protein 3 | 0 | 0 |
| K09049 | cyclic AMP-dependent transcription factor ATF-6 beta | 0 | 0 |
| K09093 | aryl hydrocarbon receptor | 0 | 0 |
| K09097 | aryl hydrocarbon receptor nuclear translocator | 0 | 0 |
| K09206 | krueppel-like factor 5 | 0 | 0 |
| K09487 | heat shock protein 90kDa beta | 0 | 0 |
| K10152 | G1/S-specific cyclin-D3 | 0 | 0 |
| K11223 | signal transducer and activator of transcription 5A | 0 | 0 |
| K11224 | signal transducer and activator of transcription 5B | 0 | 0 |
| K14293 | importin subunit beta-1 | 0 | 0 |
| K15042 | importin subunit alpha-6/7 | 0 | 0 |
| K15043 | importin subunit alpha-1/8 | 0 | 0 |
| K15618 | B-cell lymphoma 6 protein | 0 | 0 |
| K15730 | cytosolic prostaglandin-E synthase [EC:5.3.99.3] | 0 | 0 |
| K16980 | microRNA let-7 | 0 | 0 |
| K16995 | microRNA 29a | 0 | 0 |
| K16996 | microRNA 29b | 0 | 0 |
| K16997 | microRNA 29c | 0 | 0 |
| K17018 | microRNA 141 | 0 | 0 |
| K17454 | transcription factor E2F1 | 0 | 0 |
| K17689 | cytochrome P450 family 3 subfamily A4 [EC:1.14.13.32 1.14.14.55 1.14.14.56 1.14.14.57 1.14.14.73 1.14.14.-] | 0 | 0 |
| K17709 | cytochrome P450 family 2 subfamily B6 [EC:1.14.14.-] | 0 | 0 |
| K17767 | AH receptor-interacting protein | 0 | 0 |
| K17846 | krueppel-like factor 4 | 0 | 0 |
| K18497 | fibroblast growth factor 2 | 0 | 0 |
| K19662 | classical protein kinase C beta type [EC:2.7.11.13] | 0 | 0 |
| K19663 | classical protein kinase C gamma type [EC:2.7.11.13] | 0 | 0 |
| K20994 | Notch 2 | 0 | 0 |
| K22368 | epoxide hydrolase 3 [EC:3.3.2.10] | 0 | 0 |
| K22369 | epoxide hydrolase 4 [EC:3.3.-.-] | 0 | 0 |
| K23583 | importin subunit alpha-4/3 | 0 | 0 |
| K23940 | importin subunit alpha-5 | 0 | 0 |
| K25039 | membrane progestin receptor alpha | 0 | 0 |
| K25040 | membrane progestin receptor beta | 0 | 0 |
| K25041 | membrane progestin receptor gamma | 0 | 0 |