Help to interpret the results
The page contains two contents:
General: this table lists the KO entries and their description specific to this pathway, and provides their frequencies in Morganella morganii S1 and in the whole dataset.
Profile + homologs: the distribution of the Kegg entries of HIF-1 signaling pathway Kegg pathway is displayed here. Given a Kegg entry and a genome, a red box indicates that one or more loci have been annotated with, while a green box indicates that no locus/loci has(have) been annotated with it, but it/they is/are part of an Orthologous group in which other members have been annotated with that Kegg entry, so it is likely that this copy(ies) also performs this Kegg function.
Check the composition of the HIF-1 signaling pathway pathway
| KO | Description | #in this genome | All occurrences |
|---|---|---|---|
| K00016 | L-lactate dehydrogenase [EC:1.1.1.27] | 0 | 0 |
| K00134 | glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] | 1 | 7 |
| K00161 | pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1] | 0 | 0 |
| K00162 | pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1] | 0 | 0 |
| K00510 | heme oxygenase 1 [EC:1.14.14.18] | 0 | 0 |
| K00844 | hexokinase [EC:2.7.1.1] | 0 | 0 |
| K00850 | 6-phosphofructokinase 1 [EC:2.7.1.11] | 1 | 6 |
| K00922 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153] | 0 | 0 |
| K00927 | phosphoglycerate kinase [EC:2.7.2.3] | 1 | 7 |
| K01103 | 6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 3 [EC:2.7.1.105 3.1.3.46] | 0 | 0 |
| K01116 | phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11] | 0 | 0 |
| K01623 | fructose-bisphosphate aldolase, class I [EC:4.1.2.13] | 0 | 0 |
| K01689 | enolase [EC:4.2.1.11] | 1 | 7 |
| K02161 | apoptosis regulator Bcl-2 | 0 | 0 |
| K02580 | nuclear factor NF-kappa-B p105 subunit | 0 | 0 |
| K02649 | phosphoinositide-3-kinase regulatory subunit alpha/beta/delta | 0 | 0 |
| K02677 | classical protein kinase C alpha type [EC:2.7.11.13] | 0 | 0 |
| K02991 | small subunit ribosomal protein S6e | 0 | 0 |
| K03159 | lymphotoxin beta receptor TNFR superfamily member 3 | 0 | 0 |
| K03259 | translation initiation factor 4E | 0 | 0 |
| K03868 | E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32] | 0 | 0 |
| K03870 | cullin 2 | 0 | 0 |
| K03871 | von Hippel-Lindau disease tumor supressor | 0 | 0 |
| K03872 | elongin-C | 0 | 0 |
| K03873 | elongin-B | 0 | 0 |
| K03982 | plasminogen activator inhibitor 1 | 0 | 0 |
| K04357 | epidermal growth factor | 0 | 0 |
| K04361 | epidermal growth factor receptor [EC:2.7.10.1] | 0 | 0 |
| K04368 | mitogen-activated protein kinase kinase 1 [EC:2.7.12.2] | 0 | 0 |
| K04369 | mitogen-activated protein kinase kinase 2 [EC:2.7.12.2] | 0 | 0 |
| K04371 | mitogen-activated protein kinase 1/3 [EC:2.7.11.24] | 0 | 0 |
| K04372 | MAP kinase interacting serine/threonine kinase [EC:2.7.11.1] | 0 | 0 |
| K04456 | RAC serine/threonine-protein kinase [EC:2.7.11.1] | 0 | 0 |
| K04498 | E1A/CREB-binding protein [EC:2.3.1.48] | 0 | 0 |
| K04515 | calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17] | 0 | 0 |
| K04526 | insulin | 0 | 0 |
| K04527 | insulin receptor [EC:2.7.10.1] | 0 | 0 |
| K04687 | interferon gamma | 0 | 0 |
| K04688 | ribosomal protein S6 kinase beta [EC:2.7.11.1] | 0 | 0 |
| K04692 | signal transducer and activator of transcription 3 | 0 | 0 |
| K04735 | transcription factor p65 | 0 | 0 |
| K05055 | interleukin 6 receptor | 0 | 0 |
| K05083 | receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1] | 0 | 0 |
| K05087 | insulin-like growth factor 1 receptor [EC:2.7.10.1] | 0 | 0 |
| K05096 | FMS-like tyrosine kinase 1 [EC:2.7.10.1] | 0 | 0 |
| K05121 | endothelial-specific receptor tyrosine kinase [EC:2.7.10.1] | 0 | 0 |
| K05132 | interferon gamma receptor 1 | 0 | 0 |
| K05133 | interferon gamma receptor 2 | 0 | 0 |
| K05405 | interleukin 6 | 0 | 0 |
| K05437 | erythropoietin | 0 | 0 |
| K05448 | vascular endothelial growth factor A | 0 | 0 |
| K05459 | insulin-like growth factor 1 | 0 | 0 |
| K05465 | angiopoietin 1 | 0 | 0 |
| K05466 | angiopoietin 2 | 0 | 0 |
| K05467 | angiopoietin 4 | 0 | 0 |
| K05859 | phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11] | 0 | 0 |
| K06503 | transferrin receptor | 0 | 0 |
| K06624 | cyclin-dependent kinase inhibitor 1B | 0 | 0 |
| K06625 | cyclin-dependent kinase inhibitor 1A | 0 | 0 |
| K07203 | serine/threonine-protein kinase mTOR [EC:2.7.11.1] | 0 | 0 |
| K07205 | eukaryotic translation initiation factor 4E binding protein 1 | 0 | 0 |
| K07299 | MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1 | 0 | 0 |
| K08268 | hypoxia-inducible factor 1 alpha | 0 | 0 |
| K09097 | aryl hydrocarbon receptor nuclear translocator | 0 | 0 |
| K09592 | hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29] | 0 | 0 |
| K10160 | toll-like receptor 4 | 0 | 0 |
| K12077 | pyruvate dehydrogenase kinase isoform 1 [EC:2.7.11.2] | 0 | 0 |
| K12334 | natriuretic peptide A | 0 | 0 |
| K13241 | nitric-oxide synthase, inducible [EC:1.14.13.39] | 0 | 0 |
| K13242 | nitric-oxide synthase, endothelial [EC:1.14.13.39] | 0 | 0 |
| K14736 | transferrin | 0 | 0 |
| K16366 | endothelin-1 | 0 | 0 |
| K16451 | metalloproteinase inhibitor 1 | 0 | 0 |
| K19662 | classical protein kinase C beta type [EC:2.7.11.13] | 0 | 0 |
| K19663 | classical protein kinase C gamma type [EC:2.7.11.13] | 0 | 0 |
| K21421 | NADPH oxidase 2 [EC:1.-.-.-] | 0 | 0 |