Nicotinate and nicotinamide metabolism
Help to interpret the results
The page contains two contents:
General: this table lists the KO entries and their description specific to this pathway, and provides their frequencies in Morganella morganii S5 and in the whole dataset.
Profile + homologs: the distribution of the Kegg entries of Nicotinate and nicotinamide metabolism Kegg pathway is displayed here. Given a Kegg entry and a genome, a red box indicates that one or more loci have been annotated with, while a green box indicates that no locus/loci has(have) been annotated with it, but it/they is/are part of an Orthologous group in which other members have been annotated with that Kegg entry, so it is likely that this copy(ies) also performs this Kegg function.
Check the composition of the Nicotinate and nicotinamide metabolism pathway
| KO | Description | #in this genome | All occurrences |
|---|---|---|---|
| K00135 | succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] | 1 | 7 |
| K00157 | aldehyde oxidase [EC:1.2.3.1] | 0 | 0 |
| K00278 | L-aspartate oxidase [EC:1.4.3.16] | 0 | 0 |
| K00322 | NAD(P) transhydrogenase [EC:1.6.1.1] | 1 | 7 |
| K00323 | proton-translocating NAD(P)+ transhydrogenase [EC:7.1.1.1] | 0 | 0 |
| K00324 | proton-translocating NAD(P)+ transhydrogenase subunit alpha [EC:7.1.1.1] | 1 | 7 |
| K00325 | proton-translocating NAD(P)+ transhydrogenase subunit beta [EC:7.1.1.1] | 1 | 7 |
| K00541 | nicotinamide N-methyltransferase [EC:2.1.1.1] | 0 | 0 |
| K00763 | nicotinate phosphoribosyltransferase [EC:6.3.4.21] | 1 | 7 |
| K00767 | nicotinate-nucleotide pyrophosphorylase (carboxylating) [EC:2.4.2.19] | 0 | 0 |
| K00858 | NAD+ kinase [EC:2.7.1.23] | 2 | 14 |
| K00952 | nicotinamide-nucleotide adenylyltransferase [EC:2.7.7.1] | 0 | 0 |
| K00969 | nicotinate-nucleotide adenylyltransferase [EC:2.7.7.18] | 1 | 7 |
| K01081 | 5'-nucleotidase [EC:3.1.3.5] | 0 | 1 |
| K01240 | uridine nucleosidase [EC:3.2.2.3] | 0 | 0 |
| K01242 | ADP-ribosyl cyclase 1 [EC:3.2.2.6 2.4.99.20] | 0 | 0 |
| K01440 | nicotinamidase [EC:3.5.1.19] | 0 | 0 |
| K01513 | ectonucleotide pyrophosphatase/phosphodiesterase family member 1/3 [EC:3.1.4.1 3.6.1.9] | 0 | 0 |
| K01799 | maleate isomerase [EC:5.2.1.1] | 0 | 0 |
| K01916 | NAD+ synthase [EC:6.3.1.5] | 0 | 0 |
| K01950 | NAD+ synthase (glutamine-hydrolysing) [EC:6.3.5.1] | 1 | 7 |
| K02566 | 5'-nucleotidase [EC:3.1.3.5] | 0 | 0 |
| K03426 | NAD+ diphosphatase [EC:3.6.1.22] | 1 | 7 |
| K03462 | nicotinamide phosphoribosyltransferase [EC:2.4.2.12] | 0 | 0 |
| K03517 | quinolinate synthase [EC:2.5.1.72] | 0 | 0 |
| K03742 | nicotinamide-nucleotide amidase [EC:3.5.1.42] | 0 | 0 |
| K03743 | nicotinamide-nucleotide amidase [EC:3.5.1.42] | 1 | 7 |
| K03783 | purine-nucleoside phosphorylase [EC:2.4.2.1] | 1 | 6 |
| K03784 | purine-nucleoside phosphorylase [EC:2.4.2.1] | 2 | 13 |
| K03787 | 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6] | 1 | 7 |
| K04765 | nucleoside triphosphate diphosphatase [EC:3.6.1.9] | 1 | 7 |
| K06210 | nicotinamide mononucleotide adenylyltransferase [EC:2.7.7.1 2.7.7.18] | 0 | 0 |
| K06211 | HTH-type transcriptional regulator, transcriptional repressor of NAD biosynthesis genes [EC:2.7.7.1 2.7.1.22] | 1 | 7 |
| K06989 | aspartate dehydrogenase [EC:1.4.1.21] | 0 | 0 |
| K08281 | nicotinamidase/pyrazinamidase [EC:3.5.1.19 3.5.1.-] | 1 | 7 |
| K08324 | succinate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.24] | 0 | 0 |
| K08693 | 2',3'-cyclic-nucleotide 2'-phosphodiesterase / 3'-nucleotidase / 5'-nucleotidase [EC:3.1.4.16 3.1.3.6 3.1.3.5] | 0 | 0 |
| K10524 | nicotinamide/nicotinate riboside kinase [EC:2.7.1.22 2.7.1.173] | 0 | 0 |
| K11121 | NAD-dependent protein deacetylase SIR2 [EC:2.3.1.286] | 0 | 0 |
| K11411 | NAD-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286] | 0 | 0 |
| K11412 | NAD-dependent protein deacetylase sirtuin 2 [EC:2.3.1.286] | 0 | 0 |
| K11413 | NAD-dependent protein deacetylase sirtuin 3 [EC:2.3.1.286] | 0 | 0 |
| K11414 | NAD-dependent protein deacetylase/lipoamidase sirtuin 4 [EC:2.3.1.286 2.3.1.313] | 0 | 0 |
| K11415 | NAD-dependent protein deacetylase sirtuin 5 [EC:2.3.1.286] | 0 | 0 |
| K11416 | NAD-dependent protein deacetylase sirtuin 6 [EC:2.3.1.286] | 0 | 0 |
| K11417 | NAD-dependent protein deacetylase sirtuin 7 [EC:2.3.1.286] | 0 | 0 |
| K11751 | 5'-nucleotidase / UDP-sugar diphosphatase [EC:3.1.3.5 3.6.1.45] | 1 | 7 |
| K12410 | NAD-dependent protein deacetylase/lipoamidase [EC:2.3.1.286 2.3.1.313] | 1 | 7 |
| K13522 | bifunctional NMN adenylyltransferase/nudix hydrolase [EC:2.7.7.1 3.6.1.-] | 0 | 0 |
| K13995 | maleamate amidohydrolase [EC:3.5.1.107] | 0 | 0 |
| K14974 | 6-hydroxynicotinate 3-monooxygenase [EC:1.14.13.114] | 0 | 0 |
| K15357 | N-formylmaleamate deformylase [EC:3.5.1.106] | 0 | 0 |
| K15358 | enamidase [EC:3.5.2.18] | 0 | 0 |
| K15359 | 6-hydroxy-3-succinoylpyridine 3-monooxygenase [EC:1.14.13.163] | 0 | 0 |
| K18028 | 2,5-dihydroxypyridine 5,6-dioxygenase [EC:1.13.11.9] | 0 | 0 |
| K18029 | nicotinate dehydrogenase subunit A [EC:1.17.2.1] | 0 | 0 |
| K18030 | nicotinate dehydrogenase subunit B [EC:1.17.2.1] | 0 | 0 |
| K18152 | ADP-ribosyl cyclase 2 [EC:3.2.2.6 2.4.99.20] | 0 | 0 |
| K18153 | NAD+ glycohydrolase [EC:3.2.2.5] | 0 | 0 |
| K18276 | 6-hydroxy-3-succinoylpyridine 3-monooxygenase [EC:1.14.13.163] | 0 | 0 |
| K18550 | IMP and pyridine-specific 5'-nucleotidase [EC:3.1.3.99 3.1.3.-] | 0 | 0 |
| K18551 | pyrimidine and pyridine-specific 5'-nucleotidase [EC:3.1.3.-] | 0 | 0 |
| K19185 | 6-hydroxypseudooxynicotine dehydrogenase subunit alpha [EC:1.5.99.14] | 0 | 0 |
| K19186 | 6-hydroxypseudooxynicotine dehydrogenase subunit beta [EC:1.5.99.14] | 0 | 0 |
| K19187 | 6-hydroxypseudooxynicotine dehydrogenase subunit gamma [EC:1.5.99.14] | 0 | 0 |
| K19188 | 2,6-dihydroxypseudooxynicotine hydrolase [EC:3.7.1.19] | 0 | 0 |
| K19189 | 2,6-dihydroxypyridine 3-monooxygenase [EC:1.14.13.10] | 0 | 0 |
| K19190 | nicotine blue oxidoreductase [EC:1.1.1.328] | 0 | 0 |
| K19191 | 4-methylaminobutanoate oxidase (formaldehyde-forming) [EC:1.5.3.19] | 0 | 0 |
| K19647 | 2-hydroxymethylglutarate dehydrogenase [EC:1.1.1.291] | 0 | 0 |
| K19700 | 3-succinoylsemialdehyde-pyridine dehydrogenase [EC:1.2.1.83] | 0 | 0 |
| K19785 | nicotinamide-nucleotide adenylyltransferase [EC:2.7.7.1] | 0 | 0 |
| K19818 | nicotine dehydrogenase subunit A [EC:1.5.99.4] | 0 | 0 |
| K19819 | nicotine dehydrogenase subunit B [EC:1.5.99.4] | 0 | 0 |
| K19820 | nicotine dehydrogenase subunit C [EC:1.5.99.4] | 0 | 0 |
| K19826 | (S)-6-hydroxynicotine oxidase [EC:1.5.3.5] | 0 | 0 |
| K19890 | (R)-6-hydroxynicotine oxidase [EC:1.5.3.6] | 0 | 0 |
| K19970 | 5'-nucleotidase [EC:3.1.3.5] | 0 | 0 |
| K19980 | ADP-ribosyltransferase 2 / NAD+ glycohydrolase [EC:2.4.2.31 3.2.2.5] | 0 | 0 |
| K20155 | 4-methylaminobutanoate oxidase (methylamine-forming) [EC:1.5.3.21] | 0 | 0 |
| K20158 | pseudooxynicotine dehydrogenase [EC:1.4.2.3] | 0 | 0 |
| K20169 | nicotine dehydrogenase [EC:1.4.2.2] | 0 | 0 |
| K20170 | nicotine oxidoreductase | 0 | 0 |
| K20171 | 3-succinoylpyridine monooxygenase subunit A | 0 | 0 |
| K20172 | 3-succinoylpyridine monooxygenase subunit C | 0 | 0 |
| K20445 | nicotinate dehydrogenase FAD-subunit [EC:1.17.1.5] | 0 | 0 |
| K20446 | nicotinate dehydrogenase small FeS subunit [EC:1.17.1.5] | 0 | 0 |
| K20447 | nicotinate dehydrogenase large molybdopterin subunit [EC:1.17.1.5] | 0 | 0 |
| K20448 | nicotinate dehydrogenase medium molybdopterin subunit [EC:1.17.1.5] | 0 | 0 |
| K20449 | 6-hydroxynicotinate reductase [EC:1.3.7.1] | 0 | 0 |
| K20450 | 2-methyleneglutarate mutase [EC:5.4.99.4] | 0 | 0 |
| K20451 | methylitaconate Delta-isomerase [EC:5.3.3.6] | 0 | 0 |
| K20452 | dimethylmaleate hydratase large subunit [EC:4.2.1.85] | 0 | 0 |
| K20453 | dimethylmaleate hydratase small subunit [EC:4.2.1.85] | 0 | 0 |
| K20454 | 2,3-dimethylmalate lyase [EC:4.1.3.32] | 0 | 0 |
| K26956 | ADP-ribose/NAD+ diphosphatase [EC:3.6.1.13 3.6.1.22] | 0 | 0 |