Orthogroup:group_3133


Homologs in group_3133

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6 homologs were identified in 1 genome with OrthoFinder.
The following table displays the locus tag of each homolog, the organism to which it belongs, the gene name and product.

Locus tag Source Gene Product
PMI_RS00020 PMI_RS00020 Proteus mirabilis HI4320 - calcium-binding protein
PMI_RS01360 PMI_RS01360 Proteus mirabilis HI4320 - M10 family metallopeptidase
PMI_RS01365 PMI_RS01365 Proteus mirabilis HI4320 - M10 family metallopeptidase C-terminal domain-containing protein
PMI_RS01370 PMI_RS01370 Proteus mirabilis HI4320 - M10 family metallopeptidase C-terminal domain-containing protein
PMI_RS01375 PMI_RS01375 Proteus mirabilis HI4320 - M10 family metallopeptidase C-terminal domain-containing protein
PMI_RS10070 PMI_RS10070 Proteus mirabilis HI4320 rtxA MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin RtxA

Distribution of group_3133 homologs

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Number of homologs in each genome (first column and blue bar chart)

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Phylogeny of group_3133 (midpoint rooted)


Phylogeny of the RefSeq best hits of group_3133

Orthogroup content: 6 members

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This page summarizes the annotation of all members of the orthologous group group_3133.
Gene name(s), gene product(s), a summary of protein lenght, and annotations (when available) are provided. Additionally, the number of times (occurence) an annotation is observed in the orthogroup is reported for each annotation.

Orthologs were identified with OrthoFinder. The annotation of orthologous proteins can differ depending the approach used to annotate the source genomes. Automated annotations are also subject to errors. Spurious clustering of non-orthologous proteins can also happen. This page allows to check for eventual inconsistencies.

Gene

# Gene name Occurence
1 - 5
2 rtxA 1

Product

# Product Occurence
1 calcium-binding protein 1
2 M10 family metallopeptidase 1
3 M10 family metallopeptidase C-terminal domain-containing protein 3
4 MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin RtxA 1

COG entry Annotation(s)

ID Occurences Function(s) cat. Function(s) descr. Description
COG1073 1 T Signal transduction mechanisms (T) Fermentation-respiration switch esterase FrsA, DUF1100 family
COG2931 5 Q Secondary metabolites biosynthesis, transport and catabolism (Q) Ca2+-binding protein, RTX toxin-related

Kegg Ortholog Annotation(s)

KO Occurences Description Pathways Modules
K01406 5 serralysin [EC:3.4.24.40] Cationic antimicrobial peptide (CAMP) resistance -
K10953 1 RTX toxin RtxA Vibrio cholerae infection Vibrio cholerae pathogenicity signature, cholera toxins

Pfam domain Annotation(s)

Domain ID Occurences Description
PF00353 5 RTX calcium-binding nonapeptide repeat (4 copies)
PF00413 3 Matrixin
PF07634 1 RtxA repeat
PF08548 4 Peptidase M10 serralysin C terminal
PF11647 1 Membrane Localization Domain
PF11713 1 Peptidase C80 family
PF12146 1 Serine aminopeptidase, S33

Annotations of the 101 SwissProt hits

Annotation Number of occurrences
Alginate lyase 7 1
Alpha/beta hydrolase domain-containing protein 17A 4
Alpha/beta hydrolase domain-containing protein 17B 6
Alpha/beta hydrolase domain-containing protein 17C 8
Alpha/beta hydrolase domain-containing protein aho-3 1
Bifunctional hemolysin/adenylate cyclase 3
Collagen-like protein V6 1
Cytolysin RtxA 1
Cytotoxin-L 2
Exotoxin PaxA 1
Hemolysin 1
Hemolysin, chromosomal 1
Hemolysin, plasmid 1
Iron-regulated protein FrpA 2
Iron-regulated protein FrpC 2
Leukotoxin 17
Lysophosphatidylserine lipase ABHD12 8
Mannuronan C5-epimerase AlgE1 1
Mannuronan C5-epimerase AlgE2 1
Mannuronan C5-epimerase AlgE3 1
Mannuronan C5-epimerase AlgE4 1
Mannuronan C5-epimerase AlgE5 1
Mannuronan C5-epimerase AlgE6 1
Metallopeptidase AprA 1
Metalloprotease AprA 1
Multifunctional-autoprocessing repeats-in-toxin 2
Nodulation protein O 1
Protein ABHD12B 1
Protein ABHD13 5
Protein bem46 1
Putative alpha/beta hydrolase L404 1
RTX-I toxin determinant A from serotypes 1/9 1
RTX-I toxin determinant A from serotypes 5/10 1
RTX-II toxin determinant A 1
RTX-III toxin determinant A from serotype 2 1
RTX-III toxin determinant A from serotype 8 1
S-layer protein 1
Serralysin 7
Serralysin A 1
Serralysin B 1
Serralysin C 2
Serralysin G 1
Uncharacterized membrane protein YNL320W 1
Uncharacterized protein MT2364 1
Uncharacterized protein R595 1
Uncharacterized protein Rv2307c 1

Protein length

Min length 649
Max length 4619
Mean length (sd) 1673.2 (1672.9)
Median length 670.5

Protein length distribution