Orthogroup:group_128


Homologs in group_128

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11 homologs were identified in 7 genomes with OrthoFinder.
The following table displays the locus tag of each homolog, the organism to which it belongs, the gene name and product.

Locus tag Source Gene Product
FBDBKF_15965 FBDBKF_15965 Morganella morganii S1 acrB Multidrug efflux pump subunit AcrB
EHELCC_18570 EHELCC_18570 Morganella morganii S2 acrB Multidrug efflux pump subunit AcrB
NLDBIP_17400 NLDBIP_17400 Morganella morganii S4 acrB Multidrug efflux pump subunit AcrB
LHKJJB_17260 LHKJJB_17260 Morganella morganii S3 acrB Multidrug efflux pump subunit AcrB
HKOGLL_17135 HKOGLL_17135 Morganella morganii S5 acrB Multidrug efflux pump subunit AcrB
F4V73_RS03935 F4V73_RS03935 Morganella psychrotolerans - CusA/CzcA family heavy metal efflux RND transporter
F4V73_RS16345 F4V73_RS16345 Morganella psychrotolerans - efflux RND transporter permease subunit
F4V73_RS17010 F4V73_RS17010 Morganella psychrotolerans - efflux RND transporter permease subunit
PMI_RS00635 PMI_RS00635 Proteus mirabilis HI4320 - efflux RND transporter permease subunit
PMI_RS13345 PMI_RS13345 Proteus mirabilis HI4320 - MexW/MexI family multidrug efflux RND transporter permease subunit
PMI_RS17910 PMI_RS17910 Proteus mirabilis HI4320 - efflux RND transporter permease subunit

Distribution of group_128 homologs

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Number of homologs in each genome (first column and blue bar chart)

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Phylogeny of group_128 (midpoint rooted)


Phylogeny of the RefSeq best hits of group_128

Orthogroup content: 11 members

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This page summarizes the annotation of all members of the orthologous group group_128.
Gene name(s), gene product(s), a summary of protein lenght, and annotations (when available) are provided. Additionally, the number of times (occurence) an annotation is observed in the orthogroup is reported for each annotation.

Orthologs were identified with OrthoFinder. The annotation of orthologous proteins can differ depending the approach used to annotate the source genomes. Automated annotations are also subject to errors. Spurious clustering of non-orthologous proteins can also happen. This page allows to check for eventual inconsistencies.

Gene

# Gene name Occurence
1 acrB 5
2 - 6

Product

# Product Occurence
1 Multidrug efflux pump subunit AcrB 5
2 CusA/CzcA family heavy metal efflux RND transporter 1
3 efflux RND transporter permease subunit 4
4 MexW/MexI family multidrug efflux RND transporter permease subunit 1

COG entry Annotation(s)

ID Occurences Function(s) cat. Function(s) descr. Description
COG0841 10 V Defense mechanisms (V) Multidrug efflux pump subunit AcrB
COG3696 1 P Inorganic ion transport and metabolism (P) Cu/Ag efflux pump CusA

Kegg Ortholog Annotation(s)

KO Occurences Description Pathways Modules
K07787 1 copper/silver efflux system protein Two-component system -
K18138 8 multidrug efflux pump beta-Lactam resistance
Cationic antimicrobial peptide (CAMP) resistance		 Multidrug resistance, efflux pump MexAB-OprM
K18307 1 multidrug efflux pump Quorum sensing -
K19594 1 gold/copper resistance efflux pump - Multidrug resistance, efflux pump MexPQ-OpmE

Pfam domain Annotation(s)

Domain ID Occurences Description
PF00873 11 AcrB/AcrD/AcrF family

Virulence factor Annotation(s)

VF gene ID Occurences Protein VF ID Category
VFG049139 5 acriflavine resistance protein B VF0568 Antimicrobial activity/Competitive advantage
VFG049144 1 acriflavine resistance protein B VF0568 Antimicrobial activity/Competitive advantage
VFG049146 1 acriflavine resistance protein B VF0568 Antimicrobial activity/Competitive advantage

Annotations of the 152 SwissProt hits

Annotation Number of occurrences
Antibiotic efflux pump membrane transporter ArpB 1
Cation efflux system protein CusA 3
Cation efflux system protein CzcA 1
Cobalt-zinc-cadmium resistance protein CzcA 1
Efflux pump membrane transporter BepE 1
Efflux pump membrane transporter BepG 1
Multidrug efflux pump subunit AcrB 1
Multidrug export protein AcrF 1
Multidrug resistance protein MdtB 55
Multidrug resistance protein MdtC 66
Multidrug resistance protein MdtF 3
Multidrug resistance protein MexB 1
Multidrug/solvent efflux pump membrane transporter MepB 1
NPC intracellular sterol transporter 1-related protein 1 1
Nickel and cobalt resistance protein CnrA 1
Nickel-cobalt-cadmium resistance protein NccA 1
Nodulation protein NolG 1
Probable aminoglycoside efflux pump 1
Probable efflux pump membrane transporter SepB 1
Probable efflux pump membrane transporter TtgB 1
Protein HelA 1
Putative cation efflux system protein SilA 1
Solvent-resistant pump membrane transporter SrpB 1
Swarming motility protein SwrC 1
Toluene efflux pump membrane transporter TtgB 1
Toluene efflux pump membrane transporter TtgE 1
Toluene efflux pump membrane transporter TtgH 1
Uncharacterized 17.3 kDa protein in cblS 5'region 1
Uncharacterized transporter HI_0895 1

Protein length

Min length 1025
Max length 1058
Mean length (sd) 1051.3 (10.2)
Median length 1058.0

Protein length distribution