Homologs in group_2158

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6 homologs were identified in 6 genomes with OrthoFinder.
The following table displays the locus tag of each homolog, the organism to which it belongs, the gene name and product.

Locus tag Identity Source Gene Product
FBDBKF_16235 FBDBKF_16235 75.9 Morganella morganii S1 coaBC bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC
EHELCC_16270 EHELCC_16270 75.9 Morganella morganii S2 coaBC bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC
NLDBIP_17070 NLDBIP_17070 75.9 Morganella morganii S4 coaBC bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC
LHKJJB_16990 LHKJJB_16990 75.9 Morganella morganii S3 coaBC bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC
HKOGLL_16850 HKOGLL_16850 75.9 Morganella morganii S5 coaBC bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC
F4V73_RS17365 F4V73_RS17365 73.9 Morganella psychrotolerans coaBC bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC

Distribution of the homologs in the orthogroup group_2158

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Number of homologs in each genome (first column) and amino-acid identity of the closest homolog (second column).

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Phylogeny of the RefSeq best hits of group_2158

Swissprot accession Eval Score ID (%) N gaps Alignment length Annot score Gene Description Organism
P0ABQ0 0.0 564 70 1 403 1 coaBC Coenzyme A biosynthesis bifunctional protein CoaBC Escherichia coli (strain K12)
P0ABQ1 0.0 564 70 1 403 3 coaBC Coenzyme A biosynthesis bifunctional protein CoaBC Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Q5E8M6 0.0 522 63 2 407 3 coaBC Coenzyme A biosynthesis bifunctional protein CoaBC Aliivibrio fischeri (strain ATCC 700601 / ES114)
Q9KVD1 0.0 522 65 2 396 3 coaBC Coenzyme A biosynthesis bifunctional protein CoaBC Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Q8DDX8 0.0 520 66 2 396 3 coaBC Coenzyme A biosynthesis bifunctional protein CoaBC Vibrio vulnificus (strain CMCP6)
Q7MPS9 0.0 519 66 2 396 3 coaBC Coenzyme A biosynthesis bifunctional protein CoaBC Vibrio vulnificus (strain YJ016)
Q87T89 0.0 515 63 2 396 3 coaBC Coenzyme A biosynthesis bifunctional protein CoaBC Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)
P44953 1.02e-176 501 61 1 397 3 coaBC Coenzyme A biosynthesis bifunctional protein CoaBC Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
O35033 3.19e-104 317 45 4 396 3 coaBC Coenzyme A biosynthesis bifunctional protein CoaBC Bacillus subtilis (strain 168)
A0QWT2 9.72e-86 270 41 9 413 1 coaBC Coenzyme A biosynthesis bifunctional protein CoaBC Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)
P73881 8.04e-82 259 40 6 391 3 coaBC Coenzyme A biosynthesis bifunctional protein CoaBC Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
O51752 9.59e-82 258 37 4 388 3 coaBC Coenzyme A biosynthesis bifunctional protein CoaBC Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31)
P9WNZ1 3.73e-81 258 42 9 405 1 coaBC Coenzyme A biosynthesis bifunctional protein CoaBC Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
P9WNZ0 3.73e-81 258 42 9 405 3 coaBC Coenzyme A biosynthesis bifunctional protein CoaBC Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
P67734 3.73e-81 258 42 9 405 3 coaBC Coenzyme A biosynthesis bifunctional protein CoaBC Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
A0A2I9 2.17e-66 218 41 4 331 1 undec1A Cysteine/Cysteine sulfinic acid decarboxylase Unknown prokaryotic organism
Q5JF17 5.75e-54 187 34 11 402 3 coaBC Coenzyme A biosynthesis bifunctional protein CoaBC Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
Q58323 1.13e-36 140 26 13 401 1 coaBC Coenzyme A biosynthesis bifunctional protein CoaBC Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
Q54433 8.95e-35 129 42 1 177 3 coaC Probable phosphopantothenoylcysteine decarboxylase Streptococcus mutans serotype c (strain ATCC 700610 / UA159)
Q9UTI7 6.11e-19 92 38 6 174 3 SPAC15E1.04 Probable thymidylate synthase Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Q9SWE5 3.91e-17 82 32 5 176 1 HAL3A Phosphopantothenoylcysteine decarboxylase Arabidopsis thaliana
Q69K55 1.98e-16 81 33 4 169 1 HAL3 Phosphopantothenoylcysteine decarboxylase Oryza sativa subsp. japonica
P36076 4.17e-16 83 31 7 195 1 CAB3 Coenzyme A biosynthesis protein 3 Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
P94063 9.07e-16 78 31 5 176 2 HAL3B Probable phosphopantothenoylcysteine decarboxylase Arabidopsis thaliana
Q96CD2 4.63e-14 73 32 4 163 1 PPCDC Phosphopantothenoylcysteine decarboxylase Homo sapiens
Q8BZB2 5.73e-14 73 31 7 189 1 Ppcdc Phosphopantothenoylcysteine decarboxylase Mus musculus
Q54Y51 7.93e-13 70 29 7 175 3 ppcdc Putative phosphopantothenoylcysteine decarboxylase Dictyostelium discoideum
P30197 1.79e-12 68 23 2 159 1 epiD Epidermin decarboxylase Staphylococcus epidermidis
Q12600 2.44e-12 72 30 8 188 3 SIS2 Protein SIS2 Candida tropicalis
Q9RC23 2.2e-11 65 28 3 154 1 mrsD Mersacidin decarboxylase Bacillus sp. (strain HIL-Y85/54728)
P36024 6.22e-09 61 30 3 104 1 SIS2 Phosphopantothenoylcysteine decarboxylase subunit SIS2 Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Q08438 2.89e-08 59 29 3 105 1 VHS3 Phosphopantothenoylcysteine decarboxylase subunit VHS3 Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

  • Number of RefSeq hits:

General

Source Proteus mirabilis HI4320
Locus tag PMI_RS15600
Feature type CDS
Gene coaBC
Product bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC
Location 3467823 - 3469031 (strand: -1)
Length 1209 (nucleotides) / 402 (amino acids)

Contig

Accession NC_010554
Length 4063606 nucleotides
Topology circular
Plasmid False

Orthology

Orthogroup group_2158
Orthogroup size 7
N. genomes 7

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Genomic region

Domains

PF02441 Flavoprotein
PF04127 DNA / pantothenate metabolism flavoprotein

COG entry Annotation(s)

ID Function(s) descr. Function(s) cat. Description
COG0452 Coenzyme transport and metabolism (H) H Phosphopantothenoylcysteine synthetase/decarboxylase CoaBC

Kegg Ortholog Annotation(s)

KO Description Pathways Modules
K13038 phosphopantothenoylcysteine decarboxylase / phosphopantothenate---cysteine ligase [EC:4.1.1.36 6.3.2.5] Pantothenate and CoA biosynthesis
Metabolic pathways
Biosynthesis of cofactors		 Coenzyme A biosynthesis, pantothenate => CoA
Coenzyme A biosynthesis, archaea, 2-oxoisovalerate => 4-phosphopantoate => CoA

Protein Sequence

MTTLHDKKIILGISGGIAAYKAPELVRRLRDKGAIVRVVMTPAAHAFVTPLSLQAVSGFPVADDLLDPAAEAAMGHIELGKWADLILLAPATADLIARLRMGMANDLLTTLCLASAAPIAIAPAMNQQMYRATITQENLTALAQRGCLIWGPDSGSQACGDVGPGRMLDPLELVALAEQQFAIQHDFKGKKITITAGPTREALDPVRFISNHSSGKMGFAIAQAAAQRGAEVTLIAGPVTLPTPACVKRIDVESAQEMYQQVMNIAPSQDIFIGCAAVADYRAKQVAPEKIKKQGDEVTITMIKNPDIVASVGKMVEHRPFVVGFAAETQNVEEYARRKREQKQLDLICANDVSLKDAGFNSDNNALHLIWANGETRLPHSSKTQLSHRLLDEIAKHYDEKN

Flanking regions ( +/- flanking 50bp)

AGCTTGTGGTAAAATTATGGACATTTATTTATGCAATTAGGCATTTCATCATGACTACACTTCACGACAAAAAGATTATTCTGGGTATCAGTGGTGGTATTGCGGCCTATAAAGCGCCTGAGCTAGTCCGTCGTTTACGTGATAAAGGCGCTATTGTGCGCGTCGTTATGACGCCTGCAGCACATGCCTTTGTCACCCCGTTATCGCTACAAGCGGTATCAGGCTTCCCTGTTGCGGATGATTTGCTTGATCCTGCCGCAGAAGCCGCAATGGGACATATCGAACTAGGGAAATGGGCTGATCTGATTTTATTAGCCCCTGCTACCGCAGATTTAATTGCTCGTTTACGCATGGGGATGGCAAACGATCTGTTAACCACACTCTGTTTAGCCAGTGCAGCACCTATTGCGATTGCCCCAGCGATGAATCAACAAATGTATCGTGCGACGATTACACAAGAAAATTTAACGGCTTTGGCACAACGAGGTTGTCTTATCTGGGGGCCTGACTCTGGTAGCCAAGCCTGTGGTGATGTTGGACCCGGTAGAATGTTAGATCCTCTTGAATTGGTGGCATTAGCAGAGCAACAATTTGCAATTCAACACGATTTTAAAGGTAAAAAAATTACCATTACCGCAGGCCCAACACGTGAAGCCTTAGATCCAGTACGCTTTATCAGCAACCATAGCTCAGGAAAAATGGGCTTTGCTATTGCGCAAGCGGCCGCTCAACGGGGAGCAGAAGTGACACTCATTGCCGGCCCTGTCACATTGCCGACACCTGCTTGTGTTAAACGTATCGACGTCGAAAGTGCCCAAGAGATGTATCAACAAGTGATGAATATTGCGCCATCCCAAGATATTTTTATTGGTTGTGCTGCCGTTGCCGATTATCGAGCCAAACAGGTTGCCCCTGAAAAAATTAAAAAACAAGGTGATGAAGTAACGATAACTATGATAAAAAACCCCGATATTGTTGCCAGTGTCGGAAAAATGGTTGAGCATCGCCCATTTGTTGTCGGATTTGCAGCCGAAACCCAGAATGTGGAAGAATATGCCCGCCGTAAACGAGAACAAAAACAACTCGATTTAATCTGTGCTAATGATGTATCACTAAAAGATGCTGGTTTTAATAGTGATAACAACGCATTACACCTTATCTGGGCAAATGGAGAAACGCGTTTACCACATAGTAGTAAAACGCAACTGAGTCATCGCCTACTTGACGAGATAGCCAAACATTATGATGAAAAAAATTGACGTTAAAATCCTTGATCCACGAATTGGACAAGAGTATCCACTCCCTGCGT