Homologs in group_1084

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6 homologs were identified in 6 genomes with OrthoFinder.
The following table displays the locus tag of each homolog, the organism to which it belongs, the gene name and product.

Locus tag Identity Source Gene Product
FBDBKF_06160 FBDBKF_06160 54.5 Morganella morganii S1 ptrA pitrilysin
EHELCC_09205 EHELCC_09205 54.5 Morganella morganii S2 ptrA pitrilysin
NLDBIP_09585 NLDBIP_09585 54.5 Morganella morganii S4 ptrA pitrilysin
LHKJJB_08170 LHKJJB_08170 54.5 Morganella morganii S3 ptrA pitrilysin
HKOGLL_07720 HKOGLL_07720 54.5 Morganella morganii S5 ptrA pitrilysin
F4V73_RS15755 F4V73_RS15755 54.4 Morganella psychrotolerans ptrA pitrilysin

Distribution of the homologs in the orthogroup group_1084

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Number of homologs in each genome (first column) and amino-acid identity of the closest homolog (second column).

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Phylogeny of the RefSeq best hits of group_1084

Swissprot accession Eval Score ID (%) N gaps Alignment length Annot score Gene Description Organism
Q83QC3 0.0 1017 51 2 955 3 ptrA Protease 3 Shigella flexneri
P05458 0.0 1014 52 0 930 1 ptrA Protease 3 Escherichia coli (strain K12)
Q8CVS2 0.0 1013 51 2 956 3 ptrA Protease 3 Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Q8ZMB5 0.0 1009 50 1 951 3 ptrA Protease 3 Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Q8X6M8 0.0 1009 52 0 930 3 ptrA Protease 3 Escherichia coli O157:H7
Q8Z418 0.0 1004 50 1 951 3 ptrA Protease 3 Salmonella typhi
P22817 5.66e-106 355 26 15 914 1 Ide Insulin-degrading enzyme Drosophila melanogaster
P35559 7.58e-105 353 27 9 910 1 Ide Insulin-degrading enzyme Rattus norvegicus
P14735 1.89e-104 352 27 9 904 1 IDE Insulin-degrading enzyme Homo sapiens
Q24K02 3.6e-104 351 27 9 904 2 IDE Insulin-degrading enzyme Bos taurus
Q9JHR7 4.5e-104 351 27 9 908 1 Ide Insulin-degrading enzyme Mus musculus
O22941 2.41e-102 345 27 13 903 2 PXM16 Insulin-degrading enzyme-like 1, peroxisomal Arabidopsis thaliana
Q06010 3.13e-97 332 25 15 952 1 STE23 A-factor-processing enzyme Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
F4J3D9 1.21e-91 316 26 15 914 3 At3g57470 Insulin-degrading enzyme-like 2 Arabidopsis thaliana
O14077 2.4e-87 304 27 11 853 1 mug138 Putative zinc protease mug138 Schizosaccharomyces pombe (strain 972 / ATCC 24843)
F4HNU6 5.33e-84 295 25 17 887 2 At1g06900 Nardilysin-like Arabidopsis thaliana
Q5R4H6 6.68e-71 259 27 22 831 2 NRDC Nardilysin Pongo abelii
P47245 1.53e-70 258 26 22 831 1 Nrdc Nardilysin Rattus norvegicus
O43847 2.34e-70 258 27 22 831 1 NRDC Nardilysin Homo sapiens
Q8BHG1 4.66e-70 257 27 24 838 1 Nrdc Nardilysin Mus musculus
Q54JQ2 9.71e-59 221 23 18 808 3 DDB_G0287851 Insulin-degrading enzyme homolog Dictyostelium discoideum
Q10040 2.25e-48 189 22 21 909 3 C28F5.4 Putative zinc protease C28F5.4 Caenorhabditis elegans
P42789 4.02e-48 184 30 9 446 2 None Sporozoite developmental protein Eimeria bovis
Q88A79 7.8e-27 121 30 10 305 3 pqqF Coenzyme PQQ synthesis protein F Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)
P40851 3.57e-25 116 31 4 260 1 AXL1 Putative protease AXL1 Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Q9I2D2 1.84e-24 114 28 8 305 3 pqqF Coenzyme PQQ synthesis protein F Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Q9I2D2 6.79e-09 63 29 1 136 3 pqqF Coenzyme PQQ synthesis protein F Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Q88QV3 3.57e-21 103 30 6 235 3 pqqF Coenzyme PQQ synthesis protein F Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440)
P55174 1.6e-19 98 28 7 280 3 pqqF Coenzyme PQQ synthesis protein F Pseudomonas protegens (strain DSM 19095 / LMG 27888 / CFBP 6595 / CHA0)
P55679 8.2e-12 72 22 9 361 3 NGR_a01040 Uncharacterized zinc protease y4wA Sinorhizobium fredii (strain NBRC 101917 / NGR234)
Q00302 4.56e-11 70 26 5 242 3 MPP1 Mitochondrial-processing peptidase subunit beta Blastocladiella emersonii
P27508 6.47e-10 67 28 3 201 3 pqqF Coenzyme PQQ synthesis protein F Klebsiella pneumoniae
Q4W6B5 8.53e-09 62 26 3 164 1 mppB Mitochondrial-processing peptidase subunit beta Dictyostelium discoideum
P11913 2.23e-08 61 25 6 232 1 pep Mitochondrial-processing peptidase subunit beta Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Q68XF0 2.38e-08 61 23 7 320 3 RT0210 Uncharacterized zinc protease RT0210 Rickettsia typhi (strain ATCC VR-144 / Wilmington)
Q42290 5.21e-08 60 31 1 122 1 MPPbeta Probable mitochondrial-processing peptidase subunit beta, mitochondrial Arabidopsis thaliana
O31766 6.17e-08 60 27 3 155 3 ymfH Uncharacterized zinc protease YmfH Bacillus subtilis (strain 168)
O05945 7.38e-08 59 22 7 319 3 RP219 Uncharacterized zinc protease RP219 Rickettsia prowazekii (strain Madrid E)
Q9Y8B5 1.32e-07 58 26 5 211 3 mppB Mitochondrial-processing peptidase subunit beta Lentinula edodes
O32965 1.33e-07 58 26 5 218 3 ML0855 Uncharacterized zinc protease ML0855 Mycobacterium leprae (strain TN)
Q5UPX9 5.97e-07 56 25 6 191 3 MIMI_L233 Putative zinc protease L233 Acanthamoeba polyphaga mimivirus
Q9P7X1 7.7e-07 56 27 7 211 1 qcr1 Probable mitochondrial-processing peptidase subunit beta Schizosaccharomyces pombe (strain 972 / ATCC 24843)
O86835 9.27e-07 56 26 2 153 3 SCO5738 Uncharacterized zinc protease SCO5738 Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
P43264 1.26e-06 55 26 5 206 2 None Ubiquinol-cytochrome-c reductase complex core protein I, mitochondrial Euglena gracilis
P10507 1.3e-06 55 24 8 244 1 MAS1 Mitochondrial-processing peptidase subunit beta Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Q04805 7.65e-06 53 29 3 119 3 ymxG Uncharacterized zinc protease YmxG Bacillus subtilis (strain 168)
Q1RJ61 8.94e-06 53 21 6 317 3 RBE_0522 Uncharacterized zinc protease RBE_0522 Rickettsia bellii (strain RML369-C)
Q10068 1.65e-05 52 31 2 118 4 SPAC3H1.02c Uncharacterized protein C3H1.02c Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Q69TY5 1.72e-05 52 23 9 234 2 SPP Stromal processing peptidase, chloroplastic Oryza sativa subsp. japonica
Q40983 1.74e-05 52 25 8 199 1 SPP Stromal processing peptidase, chloroplastic Pisum sativum
Q9FJT9 1.95e-05 52 25 9 228 1 At5g56730 Zinc protease PQQL-like Arabidopsis thaliana
B8B0E2 2.32e-05 52 25 7 191 1 OsI_23765 Stromal processing peptidase, chloroplastic Oryza sativa subsp. indica
Q9FIH8 2.59e-05 52 21 9 277 2 SPP Stromal processing peptidase, chloroplastic Arabidopsis thaliana
Q92IX7 7.07e-05 50 21 7 320 3 RC0293 Uncharacterized zinc protease RC0293 Rickettsia conorii (strain ATCC VR-613 / Malish 7)
Q4UML9 7.32e-05 50 23 6 213 3 RF_0338 Uncharacterized zinc protease RF_0338 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2)
Q23295 0.000224 48 23 6 206 1 mppb-1 Mitochondrial-processing peptidase subunit beta Caenorhabditis elegans
P9WHT4 0.000261 48 25 2 186 3 MT2852 Uncharacterized zinc protease MT2852 Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
P0A5S9 0.000329 48 25 2 186 3 BQ2027_MB2805C Uncharacterized zinc protease Mb2805c Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
P9WHT5 0.000329 48 25 2 186 1 Rv2782c Uncharacterized zinc protease Rv2782c Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Q759T9 0.001 47 24 13 330 3 CYM1 Presequence protease, mitochondrial Eremothecium gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)

  • Number of RefSeq hits:

General

Source Proteus mirabilis HI4320
Locus tag PMI_RS11425
Feature type CDS
Gene ptrA
Product pitrilysin
Location 2515360 - 2518248 (strand: -1)
Length 2889 (nucleotides) / 962 (amino acids)

Contig

Accession NC_010554
Length 4063606 nucleotides
Topology circular
Plasmid False

Orthology

Orthogroup group_1084
Orthogroup size 7
N. genomes 7

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Genomic region

Domains

PF00675 Insulinase (Peptidase family M16)
PF05193 Peptidase M16 inactive domain
PF16187 Middle or third domain of peptidase_M16
PF22456 PQQ synthase PqqF-like, C-terminal lobe domain 4

COG entry Annotation(s)

ID Function(s) descr. Function(s) cat. Description
COG1025 Posttranslational modification, protein turnover, chaperones (O) O Secreted/periplasmic Zn-dependent peptidases, insulinase-like

Kegg Ortholog Annotation(s)

KO Description Pathways Modules
K01407 protease III [EC:3.4.24.55] - -

Protein Sequence

MRKYLSQLWIMLLLMLVSINSFATDPLWQVLPDSIEKSESDPRDYQAIKLANDMTVLLVSDKKAVKSLTAVALPVGALEDPDSQQGLAHYLEHMVLMGSTKYPKSGDLTEFLNKNGGSHNASTTTYRTAFYLEVENSAINEAVDRLADALAEPLLDPKYADRERNAVNAELTMARSRDGMRFWQVRAETLNPAHPSSRFMGGNLETLSDKPESKLQDELVKFYQTYYSGNLMNGVIYSNKSLDELAKLAADTFSRIPNKNTQAPVTTVPAMTEKEKGIMIHLVPAQPQKTLQIEFGIDNNLADFRSKSDEYIGYLISNRSTGTLATWLQEQGLAENISASSESYIDRNQGSFTIYVSLTDKGLAEKDKVISAIFSYIQLIQNKGVSERYFKEIANVLDLSFRYGSIVRDMNYIEDISDMMLRYPIKNILNADFIADDYQPSAILSRLGSLTPENARIWVISPNEPSNKQAYFVHAPYQVDKITAKQLASWQELASDISLSLPTLNPYIPDNLSLIDADSNITKPQLLWQDSHARLFYMPSHYFSDEPKASVTLSLVNKNADRTVKQQVIQTLTNYLADLTSSELAYQASVAGMNISSSSGRGVDFSVNGYTQHLPELVNATLKSYITFEATQQELDQAKSWYREQLEVTHNLKAYDAAMLPARRLNTIPYYEEADKLKALESITLQDIKDNRRDVIENAALQALIIGNLTPEQSREIVKSAQALLGNKGTEYWIGDTLVFDKLNQVTFQNKSKSTDNALGELFIPVGYERLQGKAITSVLSSIVHPWFFEQLRTEEQLGYAVFAFQASMGEQSGLGFLLQSNAKPPVYLNERYHAFYQQAYDRLKKLSEAEFNQYKKAIIDEVKQPPQTFYEEVSLYRNDFYRNNLKYDGREKFLAQLNKVTLKQAIEFYEKAIIKPTGLVFVSQIIGKEGNNADYAQNKQWKIYSTVSELQKTLPVEEIKE

Flanking regions ( +/- flanking 50bp)

TATTTAAGCCAATCATTCCATTTATAAAAAAATAAGGGAGCTCATATCAGATGAGAAAATACTTATCGCAACTTTGGATTATGTTGCTATTGATGCTAGTCAGTATCAACAGCTTCGCAACAGATCCACTTTGGCAAGTATTGCCGGATAGCATTGAAAAAAGTGAAAGTGATCCACGTGATTATCAGGCTATTAAATTAGCTAATGATATGACCGTATTACTGGTTTCAGATAAAAAAGCGGTCAAATCATTAACCGCCGTTGCTCTGCCTGTCGGTGCATTAGAAGATCCAGATAGCCAACAAGGTCTTGCCCACTATTTAGAACATATGGTGTTAATGGGCTCGACCAAATACCCAAAATCAGGGGATCTGACAGAGTTTTTAAATAAAAATGGTGGCTCTCATAACGCCAGCACAACCACTTACCGCACCGCATTTTATTTAGAAGTTGAAAATAGTGCCATTAATGAAGCAGTTGATCGCTTGGCAGATGCATTAGCGGAGCCATTACTTGATCCTAAATATGCTGATCGTGAACGTAATGCGGTTAATGCGGAATTAACCATGGCTCGCTCCCGCGATGGAATGCGTTTTTGGCAAGTGAGAGCTGAAACCTTGAATCCGGCTCATCCAAGCTCTCGTTTTATGGGAGGAAACTTAGAAACATTAAGTGATAAGCCAGAGAGTAAATTACAAGATGAATTAGTGAAATTCTATCAAACATACTATTCTGGTAACTTAATGAATGGGGTGATTTATAGTAATAAATCACTGGACGAACTCGCTAAATTAGCGGCTGATACTTTTTCCCGTATTCCTAATAAAAACACCCAAGCACCAGTAACGACGGTGCCTGCGATGACAGAAAAAGAAAAAGGGATAATGATCCACTTAGTCCCAGCTCAGCCACAAAAAACCTTACAAATCGAATTTGGTATTGATAATAATCTTGCCGATTTTCGCAGTAAATCAGATGAATATATTGGCTACCTTATTAGCAATCGTAGCACGGGAACACTAGCAACTTGGTTACAAGAGCAAGGATTAGCAGAGAATATTAGTGCTTCATCTGAATCCTATATCGATCGCAATCAAGGTTCATTTACCATTTATGTTTCTTTAACAGACAAAGGCCTTGCTGAGAAAGATAAAGTTATTTCAGCGATATTTTCTTATATTCAACTGATCCAAAATAAAGGGGTCAGTGAGCGCTATTTTAAAGAAATAGCCAATGTGCTTGACCTCTCATTCCGCTATGGCTCTATTGTTAGAGATATGAACTATATTGAAGATATCTCCGATATGATGCTGCGTTATCCGATTAAAAATATTCTTAATGCAGATTTTATTGCCGATGACTATCAACCTTCTGCGATCCTTTCTCGTCTAGGATCGCTTACACCAGAAAATGCGCGTATTTGGGTGATTAGCCCTAATGAGCCTTCAAATAAGCAAGCTTATTTTGTTCATGCACCTTATCAAGTGGATAAAATTACTGCGAAGCAATTAGCTTCATGGCAGGAATTAGCCAGCGACATCTCATTGTCATTACCGACACTAAACCCTTATATTCCTGATAATCTGTCACTTATTGATGCTGATAGTAACATCACTAAGCCTCAACTATTATGGCAAGACAGTCATGCTCGGTTATTCTATATGCCATCGCACTATTTTTCTGATGAGCCGAAAGCCAGTGTGACGTTAAGTTTAGTGAATAAAAATGCAGATCGCACAGTTAAACAGCAAGTTATACAAACATTGACCAATTACCTTGCTGATCTAACCTCTAGTGAACTGGCTTATCAAGCTTCTGTTGCCGGCATGAATATCTCCTCTTCTTCTGGGCGTGGAGTCGATTTCTCAGTCAATGGTTATACTCAACATTTACCAGAGCTAGTGAATGCCACACTAAAAAGCTATATAACGTTTGAAGCTACTCAGCAAGAGCTTGATCAAGCTAAATCTTGGTATCGTGAACAACTGGAAGTGACGCATAACCTTAAAGCGTATGATGCTGCAATGTTACCTGCCCGTCGCTTAAATACGATCCCTTATTATGAAGAAGCCGATAAACTTAAGGCGTTAGAGTCGATAACGTTACAAGATATTAAAGATAATCGTCGTGATGTCATTGAAAATGCAGCGCTTCAAGCATTAATTATCGGTAATTTAACGCCAGAGCAGAGCCGTGAGATAGTTAAATCGGCACAGGCATTATTAGGTAATAAAGGAACAGAATATTGGATTGGCGACACATTAGTTTTTGATAAATTAAATCAAGTTACATTCCAAAATAAATCTAAAAGCACCGATAATGCGCTAGGTGAATTGTTTATCCCTGTTGGCTATGAGCGTCTACAAGGAAAAGCAATTACATCAGTATTATCCTCTATCGTGCATCCTTGGTTCTTTGAACAACTCAGAACAGAAGAGCAATTAGGTTATGCGGTCTTTGCTTTCCAAGCTTCAATGGGTGAGCAGTCCGGTTTAGGCTTTTTACTGCAAAGTAATGCTAAACCACCTGTTTATCTCAATGAGCGCTATCATGCATTTTATCAACAAGCTTATGATCGCTTGAAAAAGCTAAGTGAAGCTGAATTTAATCAATATAAAAAAGCCATTATTGATGAAGTAAAACAACCACCGCAAACATTTTATGAAGAGGTTTCTCTTTATCGTAATGATTTCTATCGTAATAACTTAAAATATGATGGTCGTGAGAAGTTTTTAGCCCAACTGAATAAGGTAACGCTAAAACAAGCAATCGAATTTTATGAAAAAGCGATAATTAAACCGACAGGACTCGTGTTTGTTTCACAAATAATCGGGAAAGAGGGTAACAACGCTGATTATGCGCAAAATAAACAGTGGAAAATCTATTCAACCGTGAGTGAATTACAAAAAACATTACCTGTTGAGGAAATTAAAGAGTGAGTGAAGTGATACAGGCACAGGTATTAGATCCCTATACACTTCCTTTGTAT