Homologs in group_918

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6 homologs were identified in 6 genomes with OrthoFinder.
The following table displays the locus tag of each homolog, the organism to which it belongs, the gene name and product.

Locus tag Identity Source Gene Product
FBDBKF_04965 FBDBKF_04965 80.1 Morganella morganii S1 purE Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase
EHELCC_06255 EHELCC_06255 80.1 Morganella morganii S2 purE Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase
NLDBIP_06575 NLDBIP_06575 80.1 Morganella morganii S4 purE Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase
LHKJJB_03455 LHKJJB_03455 80.1 Morganella morganii S3 purE Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase
HKOGLL_06930 HKOGLL_06930 80.1 Morganella morganii S5 purE Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase
F4V73_RS16105 F4V73_RS16105 83.0 Morganella psychrotolerans purE 5-(carboxyamino)imidazole ribonucleotide mutase

Distribution of the homologs in the orthogroup group_918

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Number of homologs in each genome (first column) and amino-acid identity of the closest homolog (second column).

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Phylogeny of the RefSeq best hits of group_918

Swissprot accession Eval Score ID (%) N gaps Alignment length Annot score Gene Description Organism
P43849 1.13e-73 221 72 0 162 3 purE N5-carboxyaminoimidazole ribonucleotide mutase Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
P0AG18 3.12e-73 220 78 0 160 1 purE N5-carboxyaminoimidazole ribonucleotide mutase Escherichia coli (strain K12)
P0AG19 3.12e-73 220 78 0 160 3 purE N5-carboxyaminoimidazole ribonucleotide mutase Escherichia coli O157:H7
P72157 2.36e-72 218 66 0 159 3 purE N5-carboxyaminoimidazole ribonucleotide mutase Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Q5E1R4 2.78e-66 202 63 0 159 3 purE N5-carboxyaminoimidazole ribonucleotide mutase Aliivibrio fischeri (strain ATCC 700601 / ES114)
P12044 9.12e-65 198 61 0 157 3 purE N5-carboxyaminoimidazole ribonucleotide mutase Bacillus subtilis (strain 168)
Q87KE1 7.91e-63 194 62 0 159 3 purE N5-carboxyaminoimidazole ribonucleotide mutase Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)
Q9KVT7 1.48e-61 190 65 0 158 3 purE N5-carboxyaminoimidazole ribonucleotide mutase Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Q7MGL2 8.51e-59 183 64 0 159 3 purE N5-carboxyaminoimidazole ribonucleotide mutase Vibrio vulnificus (strain YJ016)
Q8DDD7 8.51e-59 183 64 0 159 3 purE N5-carboxyaminoimidazole ribonucleotide mutase Vibrio vulnificus (strain CMCP6)
P52558 7.65e-54 171 64 0 154 3 purE N5-carboxyaminoimidazole ribonucleotide mutase Brucella melitensis biotype 1 (strain ATCC 23456 / CCUG 17765 / NCTC 10094 / 16M)
Q8FYW3 1.22e-53 170 64 0 154 3 purE N5-carboxyaminoimidazole ribonucleotide mutase Brucella suis biovar 1 (strain 1330)
Q9WYS7 2.25e-53 170 51 1 154 1 purE N5-carboxyaminoimidazole ribonucleotide mutase Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)
Q9UY68 2.91e-52 167 50 1 162 3 purE N5-carboxyaminoimidazole ribonucleotide mutase Pyrococcus abyssi (strain GE5 / Orsay)
O58058 9.2e-51 164 48 1 159 3 purE N5-carboxyaminoimidazole ribonucleotide mutase Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
O06456 5.63e-50 161 49 1 154 3 purE N5-carboxyaminoimidazole ribonucleotide mutase Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
Q54QE4 8.16e-50 174 60 1 164 1 purC/E Bifunctional purine synthesis protein purC/E Dictyostelium discoideum
O67239 1.24e-49 160 50 1 153 3 purE N5-carboxyaminoimidazole ribonucleotide mutase Aquifex aeolicus (strain VF5)
P15567 8.61e-45 157 49 1 164 3 ade6 Phosphoribosylaminoimidazole carboxylase Schizosaccharomyces pombe (strain 972 / ATCC 24843)
P46702 1.28e-44 147 56 1 133 3 purE N5-carboxyaminoimidazole ribonucleotide mutase Mycobacterium leprae (strain TN)
Q44679 1.95e-44 147 49 1 147 3 purE N5-carboxyaminoimidazole ribonucleotide mutase Corynebacterium ammoniagenes
O74197 1.99e-44 157 47 1 162 1 ADE2 Phosphoribosylaminoimidazole carboxylase Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138)
P9WHM1 1.92e-43 145 57 1 130 1 purE N5-carboxyaminoimidazole ribonucleotide mutase Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
P9WHM0 1.92e-43 145 57 1 130 3 purE N5-carboxyaminoimidazole ribonucleotide mutase Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
P55195 3.6e-43 153 48 1 158 2 PURKE Phosphoribosylaminoimidazole carboxylase, chloroplastic (Fragment) Vigna aconitifolia
P50504 5.96e-43 152 50 1 153 3 ADE2 Phosphoribosylaminoimidazole carboxylase Schwanniomyces occidentalis
Q55498 6.59e-43 144 52 1 159 3 purE N5-carboxyaminoimidazole ribonucleotide mutase Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
Q92210 4.1e-42 150 46 1 166 3 ADE2 Phosphoribosylaminoimidazole carboxylase Candida albicans (strain SC5314 / ATCC MYA-2876)
P21264 9.92e-42 149 50 1 154 1 ADE2 Phosphoribosylaminoimidazole carboxylase Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Q01930 1.26e-40 146 52 2 148 3 ADE1 Phosphoribosylaminoimidazole carboxylase Ogataea methanolica
P0CQ36 8.17e-35 131 47 1 159 3 ADE2 Phosphoribosylaminoimidazole carboxylase Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)
P0CQ37 1.36e-34 130 47 1 159 3 ADE2 Phosphoribosylaminoimidazole carboxylase Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)
P0C017 1.17e-33 127 47 1 158 2 ADE2 Phosphoribosylaminoimidazole carboxylase Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487)
P22348 1.87e-31 118 41 2 156 3 purE Probable N5-carboxyaminoimidazole ribonucleotide mutase Methanobrevibacter smithii
P22348 6.47e-10 60 27 3 133 3 purE Probable N5-carboxyaminoimidazole ribonucleotide mutase Methanobrevibacter smithii
Q58033 2e-30 111 44 3 150 1 purE N5-carboxyaminoimidazole ribonucleotide mutase Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
P41654 9.85e-27 106 37 3 162 3 purE Probable N5-carboxyaminoimidazole ribonucleotide mutase Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)
P41654 2.98e-08 55 27 3 154 3 purE Probable N5-carboxyaminoimidazole ribonucleotide mutase Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)
O28997 3.1e-13 67 33 5 150 3 purE Phosphoribosylaminoimidazole carboxylase Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16)
Q73PV9 9.64e-10 57 28 4 157 1 purE Phosphoribosylaminoimidazole carboxylase Treponema denticola (strain ATCC 35405 / DSM 14222 / CIP 103919 / JCM 8153 / KCTC 15104)
P38024 4.23e-08 55 27 5 152 2 AIRC Multifunctional protein ADE2 Gallus gallus
P51583 4.35e-08 55 27 4 139 1 Paics Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase Rattus norvegicus
P22234 1.23e-07 53 26 4 144 1 PAICS Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase Homo sapiens
Q5RB59 2.13e-07 52 25 4 144 2 PAICS Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase Pongo abelii
Q9DCL9 2.76e-07 52 27 4 137 1 Paics Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase Mus musculus

  • Number of RefSeq hits:

General

Source Proteus mirabilis HI4320
Locus tag PMI_RS10650
Feature type CDS
Gene purE
Product 5-(carboxyamino)imidazole ribonucleotide mutase
Location 2341650 - 2342171 (strand: 1)
Length 522 (nucleotides) / 173 (amino acids)

Contig

Accession NC_010554
Length 4063606 nucleotides
Topology circular
Plasmid False

Orthology

Orthogroup group_918
Orthogroup size 7
N. genomes 7

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Genomic region

Domains

PF00731 AIR carboxylase

COG entry Annotation(s)

ID Function(s) descr. Function(s) cat. Description
COG0041 Nucleotide transport and metabolism (F) F Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase

Kegg Ortholog Annotation(s)

KO Description Pathways Modules
K01588 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18] Purine metabolism
Metabolic pathways
Biosynthesis of secondary metabolites		 De novo purine biosynthesis, PRPP + glutamine => IMP

Protein Sequence

MSSQVGLNTSSPRIAIVMGSKSDWATMCHAAEVLDTLQLPYHVEIVSAHRTPDKLFRFAEQAKENGFDVIIAGAGGAAHLPGMLAAKTLVPVLGVPVQSAALSGVDSLYSIVQMPKGIPVGTLAIGKAGAANAALLAAQILALHSADIFNALTQWRATQTQEVLNHPDPREAL

Flanking regions ( +/- flanking 50bp)

GCTCAGTTTCTCTGGCTATATCCGTTTATGCTTACAGGAGCAGTTAAGTAATGTCTTCTCAAGTTGGTCTCAATACCTCATCCCCTCGTATCGCCATTGTGATGGGTTCGAAAAGTGACTGGGCGACAATGTGTCATGCCGCAGAAGTCCTAGACACGTTACAACTTCCTTACCATGTTGAAATTGTTTCCGCACACCGAACACCGGATAAATTATTTCGTTTCGCAGAACAGGCCAAAGAGAATGGTTTTGACGTGATTATTGCGGGTGCTGGCGGTGCTGCACATTTACCGGGGATGTTGGCAGCCAAAACCTTAGTTCCTGTATTAGGGGTTCCTGTACAAAGTGCTGCATTAAGTGGTGTTGATAGCCTTTATTCTATTGTACAAATGCCGAAAGGTATTCCCGTTGGCACACTGGCTATTGGTAAAGCGGGGGCTGCTAATGCCGCGCTACTTGCCGCACAAATTTTAGCATTACACTCTGCTGATATTTTTAATGCATTAACACAATGGCGAGCAACACAAACACAAGAAGTCCTTAATCACCCTGATCCAAGGGAGGCGCTATGAAGCCGGTTTGTGTTCTTGGTAATGGACAGTTAGGTCGAATGTTACGTCAA