Homologs in group_1947

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6 homologs were identified in 6 genomes with OrthoFinder.
The following table displays the locus tag of each homolog, the organism to which it belongs, the gene name and product.

Locus tag Identity Source Gene Product
FBDBKF_14615 FBDBKF_14615 73.0 Morganella morganii S1 cobB Sir2 family NAD+-dependent deacetylase
EHELCC_15420 EHELCC_15420 73.0 Morganella morganii S2 cobB Sir2 family NAD+-dependent deacetylase
NLDBIP_15950 NLDBIP_15950 73.0 Morganella morganii S4 cobB Sir2 family NAD+-dependent deacetylase
LHKJJB_15890 LHKJJB_15890 73.0 Morganella morganii S3 cobB Sir2 family NAD+-dependent deacetylase
HKOGLL_15010 HKOGLL_15010 73.0 Morganella morganii S5 cobB Sir2 family NAD+-dependent deacetylase
F4V73_RS07410 F4V73_RS07410 71.8 Morganella psychrotolerans cobB Sir2 family NAD+-dependent deacetylase

Distribution of the homologs in the orthogroup group_1947

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Number of homologs in each genome (first column) and amino-acid identity of the closest homolog (second column).

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Phylogeny of the RefSeq best hits of group_1947

Swissprot accession Eval Score ID (%) N gaps Alignment length Annot score Gene Description Organism
B4EVF5 0.0 598 100 0 285 1 npdA NAD-dependent protein deacylase Proteus mirabilis (strain HI4320)
Q669P6 9.61e-144 407 71 2 270 3 cobB NAD-dependent protein deacylase Yersinia pseudotuberculosis serotype I (strain IP32953)
Q8ZFR1 9.61e-144 407 71 2 270 3 cobB NAD-dependent protein deacylase Yersinia pestis
P0A2F2 6.65e-139 395 72 1 267 1 cobB NAD-dependent protein deacylase Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
P0A2F3 6.65e-139 395 72 1 267 3 cobB NAD-dependent protein deacylase Salmonella typhi
P75960 2.17e-137 392 70 1 270 1 cobB NAD-dependent protein deacylase Escherichia coli (strain K12)
Q83RR8 3.7e-137 391 70 1 271 3 cobB NAD-dependent protein deacylase Shigella flexneri
Q8FIM4 4.31e-137 390 70 1 270 3 cobB NAD-dependent protein deacylase Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Q8X8E0 5.61e-137 390 70 1 270 3 cobB NAD-dependent protein deacylase Escherichia coli O157:H7
Q7MKT7 2.79e-113 329 65 2 236 3 cobB NAD-dependent protein deacylase Vibrio vulnificus (strain YJ016)
Q8D9J9 3.01e-113 329 65 2 236 3 cobB NAD-dependent protein deacylase Vibrio vulnificus (strain CMCP6)
Q9KRX4 1.65e-111 325 64 2 236 3 cobB NAD-dependent protein deacylase Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Q87PH8 3.93e-111 323 63 3 244 1 cobB NAD-dependent protein deacylase Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)
Q9CM50 1.39e-110 322 65 1 230 3 cobB NAD-dependent protein deacylase Pasteurella multocida (strain Pm70)
Q4Q2Y6 2.14e-97 289 59 2 231 3 SIR2rp3 NAD-dependent protein deacylase SIR2rp3 Leishmania major
Q584D5 1.65e-89 269 54 1 230 3 SIR2rp3 NAD-dependent protein deacylase SIR2rp3 Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Q6MJJ2 7.46e-86 259 56 2 231 3 cobB NAD-dependent protein deacylase Bdellovibrio bacteriovorus (strain ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100)
Q8EFN2 8.34e-86 259 56 1 229 3 cobB NAD-dependent protein deacylase Shewanella oneidensis (strain ATCC 700550 / JCM 31522 / CIP 106686 / LMG 19005 / NCIMB 14063 / MR-1)
Q9A2S6 1.71e-81 248 52 2 232 3 cobB NAD-dependent protein deacylase Caulobacter vibrioides (strain ATCC 19089 / CIP 103742 / CB 15)
Q7UFQ9 2.03e-80 246 55 6 233 3 cobB NAD-dependent protein deacylase Rhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1)
O25849 1.43e-54 179 50 4 188 3 cobB NAD-dependent protein deacylase Helicobacter pylori (strain ATCC 700392 / 26695)
Q8A3H9 6.12e-53 175 49 4 193 3 cobB NAD-dependent protein deacylase Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50)
Q9ZJW8 7.76e-53 175 49 4 188 3 cobB NAD-dependent protein deacylase Helicobacter pylori (strain J99 / ATCC 700824)
O67919 1.58e-52 174 42 8 230 3 cobB NAD-dependent protein deacylase Aquifex aeolicus (strain VF5)
Q9ZAB8 4.85e-51 169 48 5 193 3 cobB NAD-dependent protein deacylase Aggregatibacter actinomycetemcomitans
O58669 4.34e-50 168 39 7 241 3 cobB NAD-dependent protein deacylase Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Q8U1Q1 3.24e-49 166 40 6 234 3 cobB NAD-dependent protein deacylase Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
Q5JG47 1.88e-48 164 37 7 245 3 cobB NAD-dependent protein deacylase Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
Q72IV5 2.95e-48 164 43 5 208 3 cobB NAD-dependent protein deacylase Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27)
Q5SIH7 1.37e-47 162 43 5 208 3 cobB NAD-dependent protein deacylase Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)
Q9UZE7 4.86e-47 160 37 7 245 3 cobB NAD-dependent protein deacylase Pyrococcus abyssi (strain GE5 / Orsay)
O28597 3.08e-46 158 39 4 228 1 cobB1 NAD-dependent protein deacylase 1 Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16)
Q3ZBQ0 8.45e-46 159 38 6 247 2 SIRT5 NAD-dependent protein deacylase sirtuin-5, mitochondrial Bos taurus
Q9YB13 8.65e-46 157 41 6 209 3 cobB NAD-dependent protein deacylase Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)
Q6DHI5 1.73e-45 158 36 6 260 1 sirt5 NAD-dependent protein deacylase sirtuin-5, mitochondrial Danio rerio
Q9JN05 3.71e-45 155 40 4 206 3 cobB NAD-dependent protein deacylase Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)
Q72RR0 5.06e-45 155 36 5 244 3 cobB NAD-dependent protein deacylase Leptospira interrogans serogroup Icterohaemorrhagiae serovar copenhageni (strain Fiocruz L1-130)
C6A243 6.02e-45 155 35 7 251 3 cobB NAD-dependent protein deacylase Thermococcus sibiricus (strain DSM 12597 / MM 739)
Q8ZT00 6.33e-45 155 38 7 231 3 cobB2 NAD-dependent protein deacylase 2 Pyrobaculum aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630 / CIP 104966 / NBRC 100827 / IM2)
Q8F3Z6 6.99e-45 155 36 5 244 3 cobB NAD-dependent protein deacylase Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)
Q8R9N6 1.97e-44 154 42 7 209 3 cobB1 NAD-dependent protein deacylase 1 Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4)
O30124 2.43e-44 154 38 7 234 1 cobB2 NAD-dependent protein deacylase 2 Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16)
Q5R6G3 3.01e-44 155 35 7 275 2 SIRT5 NAD-dependent protein deacylase sirtuin-5, mitochondrial Pongo abelii
Q5HU51 4.58e-44 152 39 4 206 3 cobB NAD-dependent protein deacylase Campylobacter jejuni (strain RM1221)
Q9NXA8 9.03e-44 154 37 6 247 1 SIRT5 NAD-dependent protein deacylase sirtuin-5, mitochondrial Homo sapiens
E2RDZ6 9.83e-44 154 36 6 247 3 SIRT5 NAD-dependent protein deacylase sirtuin-5, mitochondrial Canis lupus familiaris
Q8K2C6 1.4e-43 153 36 6 251 1 Sirt5 NAD-dependent protein deacylase sirtuin-5, mitochondrial Mus musculus
A0R2N3 1.54e-43 151 37 9 246 1 sir2 NAD-dependent protein deacylase Sir2 Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)
E1BRE2 1.82e-43 153 35 6 252 3 SIRT5 NAD-dependent protein deacylase sirtuin-5, mitochondrial Gallus gallus
F7EZ75 2.03e-43 153 36 6 247 3 SIRT5 NAD-dependent protein deacylase sirtuin-5, mitochondrial Macaca mulatta
Q8TWG0 5.27e-43 150 38 9 227 3 cobB NAD-dependent protein deacylase Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)
Q9RYD4 8.99e-43 149 43 9 210 3 cobB NAD-dependent protein deacylase Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / CCUG 27074 / LMG 4051 / NBRC 15346 / NCIMB 9279 / VKM B-1422 / R1)
E9GD30 2.41e-41 146 34 5 248 3 DAPPUDRAFT_195469 NAD-dependent protein deacylase Daphnia pulex
Q7VIN2 3.67e-41 145 36 8 249 3 cobB NAD-dependent protein deacylase Helicobacter hepaticus (strain ATCC 51449 / 3B1)
Q5HZN8 9.24e-41 146 34 4 247 2 sirt5-a NAD-dependent protein deacylase sirtuin-5A, mitochondrial Xenopus laevis
Q8Y015 1.7e-40 144 37 7 232 3 cobB NAD-dependent protein deacylase Ralstonia nicotianae (strain ATCC BAA-1114 / GMI1000)
Q68FX9 2.1e-40 145 34 5 247 2 Sirt5 NAD-dependent protein deacylase sirtuin-5, mitochondrial Rattus norvegicus
F7DKV7 2.48e-40 145 34 6 256 3 sirt5 NAD-dependent protein deacylase sirtuin-5, mitochondrial Xenopus tropicalis
Q68F47 2.52e-38 140 34 5 247 2 sirt5-b NAD-dependent protein deacylase sirtuin-5B, mitochondrial Xenopus laevis
Q88BY5 7.59e-38 137 37 8 245 3 cobB NAD-dependent protein deacylase Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440)
A9SDL4 1.6e-37 138 38 8 237 3 SRT1505 NAD-dependent protein deacylase Physcomitrium patens
Q73WM7 1.05e-35 131 33 9 249 3 cobB NAD-dependent protein deacylase Mycolicibacterium paratuberculosis (strain ATCC BAA-968 / K-10)
Q9CBW6 4.67e-35 129 34 9 246 3 cobB NAD-dependent protein deacylase Mycobacterium leprae (strain TN)
P9WGG3 5.14e-35 129 32 8 252 1 cobB NAD-dependent protein deacylase Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
P9WGG2 5.14e-35 129 32 8 252 3 cobB NAD-dependent protein deacylase Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
A5U1J9 5.14e-35 129 32 8 252 1 cobB NAD-dependent protein deacylase Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra)
P66814 5.14e-35 129 32 8 252 3 cobB NAD-dependent protein deacylase Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
A0QC96 2.65e-34 127 33 9 246 3 cobB2 NAD-dependent protein deacylase 2 Mycobacterium avium (strain 104)
Q5AI90 7.64e-34 128 30 9 269 3 CAALFM_C102740CA NAD-dependent protein deacylase Candida albicans (strain SC5314 / ATCC MYA-2876)
A8NWP2 1.82e-33 127 30 5 256 3 CC1G_00083 NAD-dependent protein deacylase Coprinopsis cinerea (strain Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003)
Q9I4L0 3.14e-33 125 37 7 242 3 cobB1 NAD-dependent protein deacylase 1 Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Q97VX5 3.18e-33 125 37 8 212 1 cobB NAD-dependent protein deacetylase Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
O07595 4.36e-33 124 37 6 224 3 cobB NAD-dependent protein deacetylase Bacillus subtilis (strain 168)
F7D4X9 2.87e-32 124 35 8 245 3 SIRT5 NAD-dependent protein deacylase sirtuin-5, mitochondrial Monodelphis domestica
A0A0J9UVG7 3.47e-32 124 33 9 256 1 SIR5 NAD-dependent protein deacylase SIR5 Fusarium oxysporum f. sp. lycopersici (strain 4287 / CBS 123668 / FGSC 9935 / NRRL 34936)
Q9KEE5 5.07e-31 119 35 5 203 3 cobB NAD-dependent protein deacetylase Halalkalibacterium halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)
Q974M6 5.61e-31 119 36 6 206 3 cobB NAD-dependent protein deacetylase Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)
Q8NSM4 6.15e-31 119 33 7 227 3 cobB NAD-dependent protein deacylase Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / BCRC 11384 / CCUG 27702 / LMG 3730 / NBRC 12168 / NCIMB 10025 / NRRL B-2784 / 534)
Q5WKC8 7.58e-31 118 36 5 205 3 cobB NAD-dependent protein deacetylase Shouchella clausii (strain KSM-K16)
Q8FRV5 1.03e-30 118 35 6 208 3 cobB2 NAD-dependent protein deacylase 2 Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395)
Q5L014 2.19e-30 117 35 10 248 3 cobB1 NAD-dependent protein deacetylase 1 Geobacillus kaustophilus (strain HTA426)
Q88A13 4.8e-30 116 33 7 236 3 cobB1 NAD-dependent protein deacylase 1 Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)
Q8XNS6 6.1e-30 116 37 7 199 3 cobB NAD-dependent protein deacetylase Clostridium perfringens (strain 13 / Type A)
Q4JBN2 9.67e-30 115 35 6 216 3 cobB NAD-dependent protein deacetylase Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)
Q87W79 2.61e-29 114 34 9 240 3 cobB4 NAD-dependent protein deacylase 4 Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)
Q81BT4 4.51e-29 114 37 6 214 3 cobB NAD-dependent protein deacetylase Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NCTC 2599 / NRRL B-3711)
Q639M6 5.4e-29 114 36 5 213 3 cobB NAD-dependent protein deacetylase Bacillus cereus (strain ZK / E33L)
Q81NT6 7.5e-29 113 36 5 213 3 cobB NAD-dependent protein deacetylase Bacillus anthracis
Q735N7 1.02e-28 112 36 5 213 3 cobB NAD-dependent protein deacetylase Bacillus cereus (strain ATCC 10987 / NRS 248)
A8MBU4 1.32e-28 113 34 8 234 3 cobB NAD-dependent protein deacetylase Caldivirga maquilingensis (strain ATCC 700844 / DSM 13496 / JCM 10307 / IC-167)
Q8ELR0 4.75e-28 110 34 6 208 3 cobB NAD-dependent protein deacetylase Oceanobacillus iheyensis (strain DSM 14371 / CIP 107618 / JCM 11309 / KCTC 3954 / HTE831)
Q6HH09 8.17e-28 110 35 5 213 3 cobB NAD-dependent protein deacetylase Bacillus thuringiensis subsp. konkukian (strain 97-27)
Q607X6 8.37e-28 110 33 6 238 3 cobB NAD-dependent protein deacylase Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath)
Q7P1B9 3.8e-27 108 32 5 214 3 cobB NAD-dependent protein deacetylase Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / CCUG 213 / NBRC 12614 / NCIMB 9131 / NCTC 9757 / MK)
A9A0B2 1.2e-26 108 31 7 227 3 cobB NAD-dependent protein deacylase Desulfosudis oleivorans (strain DSM 6200 / JCM 39069 / Hxd3)
Q8ZU41 3.13e-26 106 35 9 209 3 cobB1 NAD-dependent protein deacetylase 1 Pyrobaculum aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630 / CIP 104966 / NBRC 100827 / IM2)
Q89LY4 1.43e-25 105 34 9 221 3 cobB1 NAD-dependent protein deacetylase 1 Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110)
Q8REC3 1.88e-25 104 29 8 234 3 cobB NAD-dependent protein deacetylase Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / DSM 15643 / BCRC 10681 / CIP 101130 / JCM 8532 / KCTC 2640 / LMG 13131 / VPI 4355)
Q88ZA0 2.92e-25 103 33 6 208 3 cobB NAD-dependent protein deacetylase Lactiplantibacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1)
Q9WYW0 6.06e-25 103 35 7 206 1 cobB NAD-dependent protein deacetylase Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)
Q6N6U0 2.76e-24 101 36 9 222 3 cobB NAD-dependent protein deacetylase Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)
Q899G3 3.07e-24 101 32 8 202 3 cobB NAD-dependent protein deacetylase Clostridium tetani (strain Massachusetts / E88)
Q6A5T5 3.1e-24 101 33 7 212 3 cobB NAD-dependent protein deacetylase Cutibacterium acnes (strain DSM 16379 / KPA171202)
Q8R984 6.95e-24 100 37 8 191 3 cobB2 NAD-dependent protein deacetylase 2 Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4)
B5YJW3 7.85e-24 100 34 8 210 3 cobB NAD-dependent protein deacetylase Thermodesulfovibrio yellowstonii (strain ATCC 51303 / DSM 11347 / YP87)
Q97MB4 1.42e-23 99 34 7 195 3 cobB NAD-dependent protein deacetylase Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / IAM 19013 / LMG 5710 / NBRC 13948 / NRRL B-527 / VKM B-1787 / 2291 / W)
Q8CNF4 2.2e-23 99 35 8 216 3 cobB NAD-dependent protein deacetylase Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200)
Q5HM33 2.46e-23 99 35 8 216 3 cobB NAD-dependent protein deacetylase Staphylococcus epidermidis (strain ATCC 35984 / DSM 28319 / BCRC 17069 / CCUG 31568 / BM 3577 / RP62A)
Q71W25 3.17e-23 98 33 6 185 3 cobB NAD-dependent protein deacetylase Listeria monocytogenes serotype 4b (strain F2365)
Q73KE1 3.38e-23 98 31 6 214 3 cobB NAD-dependent protein deacetylase Treponema denticola (strain ATCC 35405 / DSM 14222 / CIP 103919 / JCM 8153 / KCTC 15104)
Q8Y3U2 3.56e-23 97 32 5 186 3 cobB NAD-dependent protein deacetylase Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)
Q927A7 6.63e-23 97 32 5 185 3 cobB NAD-dependent protein deacetylase Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262)
Q5KZE8 5.55e-22 95 34 9 232 3 cobB2 NAD-dependent protein deacetylase 2 Geobacillus kaustophilus (strain HTA426)
Q839C6 8.11e-22 94 31 7 214 3 cobB NAD-dependent protein deacetylase Enterococcus faecalis (strain ATCC 700802 / V583)
Q8IE47 8.3e-22 95 28 7 224 1 Sir2A NAD-dependent protein deacylase Sir2A Plasmodium falciparum (isolate 3D7)
Q67KQ0 9.34e-22 94 33 7 213 3 cobB NAD-dependent protein deacetylase Symbiobacterium thermophilum (strain DSM 24528 / JCM 14929 / IAM 14863 / T)
Q8CJM9 9.54e-22 94 30 6 239 3 cobB2 NAD-dependent protein deacetylase 2 Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Q1JQC6 2.13e-21 95 30 9 272 2 SIRT4 NAD-dependent protein lipoamidase sirtuin-4, mitochondrial Bos taurus
P66816 2.98e-21 93 34 7 195 3 cobB NAD-dependent protein deacetylase Staphylococcus aureus (strain N315)
P66815 2.98e-21 93 34 7 195 1 cobB NAD-dependent protein deacetylase Staphylococcus aureus (strain Mu50 / ATCC 700699)
Q6GEN2 3.31e-21 93 33 8 209 3 cobB NAD-dependent protein deacetylase Staphylococcus aureus (strain MRSA252)
Q5HE07 5.14e-21 92 31 7 215 3 cobB NAD-dependent protein deacetylase Staphylococcus aureus (strain COL)
Q8NVC8 6.72e-21 92 33 8 209 3 cobB NAD-dependent protein deacetylase Staphylococcus aureus (strain MW2)
Q6G7B7 6.72e-21 92 33 8 209 3 cobB NAD-dependent protein deacetylase Staphylococcus aureus (strain MSSA476)
Q53700 7.52e-21 92 31 7 215 3 cobB NAD-dependent protein deacetylase Staphylococcus aureus (strain NCTC 8325 / PS 47)
Q5V4Q5 1.11e-20 92 30 8 242 3 cobB NAD-dependent protein deacetylase Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)
Q8R216 6.72e-20 91 33 11 239 1 Sirt4 NAD-dependent protein lipoamidase sirtuin-4, mitochondrial Mus musculus
Q9Y6E7 6.23e-18 85 30 8 239 1 SIRT4 NAD-dependent protein lipoamidase sirtuin-4, mitochondrial Homo sapiens
Q885X7 1.81e-17 82 30 12 222 3 cobB2 NAD-dependent protein deacylase 2 Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)
Q89EA6 5.12e-17 82 31 11 235 3 cobB2 NAD-dependent protein deacetylase 2 Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110)
Q20480 5.34e-17 82 28 11 247 1 sir-2.2 NAD-dependent protein deacylase sir-2.2 Caenorhabditis elegans
Q9I4E1 9.31e-17 81 28 9 245 3 cobB2 NAD-dependent protein deacylase 2 Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Q8PQK3 1.7e-16 80 30 10 236 3 cobB NAD-dependent protein deacetylase Xanthomonas axonopodis pv. citri (strain 306)
Q21921 3.84e-16 81 32 10 202 1 sir-2.1 NAD-dependent protein deacetylase sir-2.1 Caenorhabditis elegans
Q20481 1.21e-15 78 40 6 120 1 sir-2.3 NAD-dependent protein deacylase sir-2.3 Caenorhabditis elegans
Q8FUC8 2.5e-15 77 27 12 275 3 cobB1 NAD-dependent protein deacetylase 1 Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395)
C1DBX3 5.48e-15 76 29 4 226 3 cobB NAD-dependent protein deacetylase Laribacter hongkongensis (strain HLHK9)
F4P804 1.96e-14 75 29 11 252 3 BATDEDRAFT_20316 NAD-dependent protein deacylase SIR4 Batrachochytrium dendrobatidis (strain JAM81 / FGSC 10211)
A0QDH4 3.43e-14 74 26 8 247 3 cobB1 NAD-dependent protein deacetylase 1 Mycobacterium avium (strain 104)
A0A0G2JZ79 3.64e-14 75 28 11 250 3 Sirt1 NAD-dependent protein deacetylase sirtuin-1 Rattus norvegicus
Q923E4 4.01e-14 75 28 11 250 1 Sirt1 NAD-dependent protein deacetylase sirtuin-1 Mus musculus
Q8PDM9 5.32e-14 73 27 9 247 3 cobB NAD-dependent protein deacetylase Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)
Q4UZX0 5.32e-14 73 27 9 247 3 cobB NAD-dependent protein deacetylase Xanthomonas campestris pv. campestris (strain 8004)
Q60L58 6.69e-14 75 31 9 202 3 sir-2.1 NAD-dependent protein deacetylase sir-2.1 Caenorhabditis briggsae
B0RM75 6.85e-14 73 28 10 239 3 cobB NAD-dependent protein deacetylase Xanthomonas campestris pv. campestris (strain B100)
Q7VX46 1.12e-13 72 28 6 258 3 cobB NAD-dependent protein deacetylase Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)
Q7WLE5 1.12e-13 72 28 7 262 3 cobB NAD-dependent protein deacetylase Bordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50)
Q54LF0 1.54e-13 73 29 10 215 2 sir2B NAD-dependent deacetylase sir2B Dictyostelium discoideum
Q96EB6 2.16e-13 73 28 12 254 1 SIRT1 NAD-dependent protein deacetylase sirtuin-1 Homo sapiens
O59923 8.63e-13 71 30 10 216 1 SIR2 NAD-dependent histone deacetylase SIR2 Candida albicans (strain SC5314 / ATCC MYA-2876)
Q8IRR5 2.15e-12 69 33 7 166 2 Sirt4 NAD-dependent protein deacylase Sirt4 Drosophila melanogaster
Q9VK34 3.65e-12 70 26 13 275 1 Sirt1 NAD-dependent histone deacetylase sirtuin-1 Drosophila melanogaster
Q5AW69 3.87e-12 69 31 10 216 3 AN7461 NAD-dependent protein deacetylase hst2-1 Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)
Q9NTG7 4.01e-12 69 30 9 206 1 SIRT3 NAD-dependent protein deacetylase sirtuin-3, mitochondrial Homo sapiens
Q54QE6 7.14e-12 68 29 12 221 2 sir2A NAD-dependent deacetylase sir2A Dictyostelium discoideum
Q54P49 9.75e-12 68 30 9 213 2 sir2C NAD-dependent deacetylase sir2C Dictyostelium discoideum
Q8R104 1.08e-11 67 31 9 203 1 Sirt3 NAD-dependent protein deacetylase sirtuin-3 Mus musculus
Q55DB0 1.65e-11 67 26 11 230 2 sir2E NAD-dependent deacetylase sir2E Dictyostelium discoideum
Q94AQ6 2.69e-11 66 24 10 253 1 SRT2 NAD-dependent protein deacylase SRT2 Arabidopsis thaliana
Q57V41 3.66e-11 66 28 8 199 1 SIR2rp1 NAD-dependent protein deacetylase SIR2rp1 Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
P59941 6.04e-11 65 28 11 242 1 Sirt6 NAD-dependent protein deacylase sirtuin-6 Mus musculus
Q9FE17 8.68e-11 65 26 10 251 1 SRT1 NAD-dependent protein deacetylase SRT1 Arabidopsis thaliana
A9UVV1 1.79e-10 63 26 10 272 3 15984 NAD-dependent protein deacylase SIR4 Monosiga brevicollis
Q9RL35 1.81e-10 63 29 8 194 3 cobB1 NAD-dependent protein deacetylase 1 Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Q7XWV4 2.44e-10 64 25 9 242 1 SRT1 NAD-dependent protein deacetylase SRT1 Oryza sativa subsp. japonica
B8ARK7 4.28e-10 63 25 9 242 1 SRT1 NAD-dependent protein deacetylase SRT1 Oryza sativa subsp. indica
P53685 1.25e-09 62 25 11 289 1 HST1 NAD-dependent protein deacetylase HST1 Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
P0CS88 1.61e-09 61 30 11 202 3 AN11873 NAD-dependent protein deacetylase hst2-2 Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)
Q5RBF1 1.64e-09 61 29 11 213 1 SIRT2 NAD-dependent protein deacetylase sirtuin-2 Pongo abelii
Q57YZ9 1.7e-09 61 27 11 256 3 SIR2rp2 NAD-dependent protein deacylase SIR2rp2 Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Q25337 1.77e-09 61 29 10 202 2 SIR2rp1 NAD-dependent protein deacetylase SIR2rp1 Leishmania major
P53686 2.16e-09 60 31 12 219 1 HST2 NAD-dependent protein deacetylase HST2 Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Q882K4 2.86e-09 60 25 9 266 3 cobB3 NAD-dependent protein deacetylase 3 Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)
A0A250YGJ5 3.6e-09 60 28 10 221 1 SIRT6 NAD-dependent protein deacylase sirtuin-6 Castor canadensis
Q8IXJ6 4.18e-09 60 29 11 213 1 SIRT2 NAD-dependent protein deacetylase sirtuin-2 Homo sapiens
Q4R834 4.62e-09 60 29 11 213 2 SIRT2 NAD-dependent protein deacetylase sirtuin-2 Macaca fascicularis
Q8N6T7 4.89e-09 60 28 10 221 1 SIRT6 NAD-dependent protein deacylase sirtuin-6 Homo sapiens
Q757M7 5.44e-09 60 26 14 293 3 SIR2 NAD-dependent histone deacetylase SIR2 Eremothecium gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
A0A2K5TU92 6.39e-09 59 28 10 221 1 SIRT6 NAD-dependent protein deacylase sirtuin-6 Macaca fascicularis
O94640 7.54e-09 59 27 12 239 1 sir2 NAD-dependent histone deacetylase sir2 Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Q5RJQ4 7.77e-09 59 28 11 212 1 Sirt2 NAD-dependent protein deacetylase sirtuin-2 Rattus norvegicus
Q9USN7 1.05e-08 58 29 13 233 3 hst2 NAD-dependent protein deacetylase hst2 Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Q8VDQ8 1.14e-08 58 29 11 212 1 Sirt2 NAD-dependent protein deacetylase sirtuin-2 Mus musculus
Q9I7I7 2.13e-07 55 28 11 206 3 Sirt2 NAD-dependent protein deacetylase Sirt2 Drosophila melanogaster
P33294 2.37e-07 55 25 10 240 3 SIR2 NAD-dependent histone deacetylase SIR2 Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
Q54GV7 3.93e-07 54 26 12 249 2 sir2D NAD-dependent deacetylase sir2D Dictyostelium discoideum
Q9VH08 4.17e-07 53 26 9 243 1 Sirt6 NAD-dependent protein deacetylase Sirt6 Drosophila melanogaster
P06700 9.79e-07 53 25 13 274 1 SIR2 NAD-dependent histone deacetylase SIR2 Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Q5A1W9 1.03e-06 53 27 11 247 3 HST3 NAD-dependent histone deacetylase HST3 Candida albicans (strain SC5314 / ATCC MYA-2876)
Q5A985 1.09e-06 52 28 10 207 3 HST2 NAD-dependent protein deacetylase HST2 Candida albicans (strain SC5314 / ATCC MYA-2876)
Q9UR39 1.22e-06 52 25 8 232 2 hst4 NAD-dependent protein deacetylase hst4 Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Q6FWI7 6.2e-06 50 23 11 276 3 SIR2 NAD-dependent histone deacetylase SIR2 Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138)
Q5BE04 1.71e-05 49 32 6 139 3 AN1226 NAD-dependent protein deacetylase hst4 Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)
Q9NRC8 6.96e-05 47 26 9 206 1 SIRT7 NAD-dependent protein deacetylase sirtuin-7 Homo sapiens
Q5AQ47 9.88e-05 47 23 12 277 3 HST1 NAD-dependent protein deacetylase HST1 Candida albicans (strain SC5314 / ATCC MYA-2876)
Q0P595 0.000176 46 25 9 206 2 SIRT7 NAD-dependent protein deacetylase sirtuin-7 Bos taurus

  • Number of RefSeq hits:

General

Source Proteus mirabilis HI4320
Locus tag PMI_RS04325
Feature type CDS
Gene cobB
Product NAD-dependent protein deacylase
Location 972138 - 972995 (strand: 1)
Length 858 (nucleotides) / 285 (amino acids)

Contig

Accession NC_010554
Length 4063606 nucleotides
Topology circular
Plasmid False

Orthology

Orthogroup group_1947
Orthogroup size 7
N. genomes 7

Actions

Genomic region

Domains

PF02146 Sir2 family

COG entry Annotation(s)

ID Function(s) descr. Function(s) cat. Description
COG0846 Posttranslational modification, protein turnover, chaperones (O) O NAD-dependent protein deacetylase, SIR2 family

Kegg Ortholog Annotation(s)

KO Description Pathways Modules
K12410 NAD-dependent protein deacetylase/lipoamidase [EC:2.3.1.286 2.3.1.313] Nicotinate and nicotinamide metabolism
Metabolic pathways		 -

Protein Sequence

MMKLKLRHRRLRKFRKIKSLRRQHSRCRYFHLTHKTEHEMNLPKVVVLTGAGISAESGIKTFRSEDGLWEEHRVEDVATPEGYHRNPKLVQQFYNERRRQLQQPSIQPNEAHYALAKLEQYLGKDNFLLVTQNIDNLHEKAGSKHILHMHGELLKVRCPQSGQVFEWKGDLSTTDYCHCCQFPSPLRPHIVWFGEMPIGMDEIYHALAQADLFIAIGTSGNVYPAAGFVHEARLTGAHTVELNLEPSLVESEFEEKHYGPASQVVDAYVHKLFDLINDPKADLTQ

Flanking regions ( +/- flanking 50bp)

TAAAGTTATCAATTTTTATTGATTGTTAAATATAAAAACCAAGGATTGCCATGATGAAACTTAAACTTCGTCATCGTCGGCTTAGGAAGTTTCGTAAGATAAAAAGTTTACGTAGACAACACTCACGTTGTCGTTATTTTCATTTAACCCATAAAACGGAACATGAAATGAATTTACCCAAAGTAGTGGTGCTAACCGGGGCGGGCATTTCGGCTGAATCAGGTATAAAAACCTTTCGATCAGAAGATGGATTGTGGGAAGAGCATCGCGTTGAAGATGTGGCAACGCCAGAGGGATATCACCGCAACCCTAAGCTGGTTCAGCAGTTTTACAATGAGCGCCGTCGTCAATTACAACAACCCTCAATTCAACCTAATGAAGCACATTATGCATTAGCAAAACTTGAGCAATATCTTGGAAAGGACAATTTCCTGCTGGTCACGCAGAATATTGATAACTTACATGAAAAAGCAGGGAGTAAACATATTCTCCATATGCATGGTGAGTTATTGAAAGTCCGCTGTCCGCAATCAGGTCAAGTTTTTGAATGGAAAGGGGATTTATCAACGACAGATTATTGCCATTGTTGCCAATTTCCCTCTCCTCTACGTCCACATATTGTTTGGTTTGGCGAAATGCCAATCGGCATGGATGAAATTTATCACGCTTTAGCACAGGCAGATCTCTTTATCGCTATTGGCACTTCGGGGAATGTCTATCCTGCTGCTGGGTTTGTCCATGAAGCACGGTTAACAGGGGCTCACACGGTTGAGCTTAACCTTGAACCTAGCTTAGTGGAGAGTGAGTTTGAAGAAAAACATTATGGCCCCGCAAGCCAAGTGGTTGATGCATATGTCCATAAATTGTTTGATTTAATTAATGATCCTAAAGCTGATTTGACGCAATAATTATTTTATAGAGTTCCCTATTATTGTTATTAGAGAGATTTAGGGGGCAA