Homologs in group_1947

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6 homologs were identified in 6 genomes with OrthoFinder.
The following table displays the locus tag of each homolog, the organism to which it belongs, the gene name and product.

Locus tag Identity Source Gene Product
FBDBKF_14615 FBDBKF_14615 100.0 Morganella morganii S1 cobB Sir2 family NAD+-dependent deacetylase
EHELCC_15420 EHELCC_15420 100.0 Morganella morganii S2 cobB Sir2 family NAD+-dependent deacetylase
LHKJJB_15890 LHKJJB_15890 100.0 Morganella morganii S3 cobB Sir2 family NAD+-dependent deacetylase
HKOGLL_15010 HKOGLL_15010 100.0 Morganella morganii S5 cobB Sir2 family NAD+-dependent deacetylase
F4V73_RS07410 F4V73_RS07410 88.3 Morganella psychrotolerans cobB Sir2 family NAD+-dependent deacetylase
PMI_RS04325 PMI_RS04325 73.0 Proteus mirabilis HI4320 cobB NAD-dependent protein deacylase

Distribution of the homologs in the orthogroup group_1947

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Number of homologs in each genome (first column) and amino-acid identity of the closest homolog (second column).

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Phylogeny of the RefSeq best hits of group_1947

Swissprot accession Eval Score ID (%) N gaps Alignment length Annot score Gene Description Organism
Q669P6 5.02e-148 419 70 1 277 3 cobB NAD-dependent protein deacylase Yersinia pseudotuberculosis serotype I (strain IP32953)
Q8ZFR1 5.02e-148 419 70 1 277 3 cobB NAD-dependent protein deacylase Yersinia pestis
B4EVF5 2.15e-147 417 71 2 285 1 npdA NAD-dependent protein deacylase Proteus mirabilis (strain HI4320)
P0A2F2 2.9e-141 401 71 1 269 1 cobB NAD-dependent protein deacylase Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
P0A2F3 2.9e-141 401 71 1 269 3 cobB NAD-dependent protein deacylase Salmonella typhi
P75960 3.22e-141 401 70 1 271 1 cobB NAD-dependent protein deacylase Escherichia coli (strain K12)
Q8FIM4 4.45e-141 401 70 1 271 3 cobB NAD-dependent protein deacylase Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Q8X8E0 5.41e-141 400 70 1 271 3 cobB NAD-dependent protein deacylase Escherichia coli O157:H7
Q83RR8 7.44e-141 400 70 1 271 3 cobB NAD-dependent protein deacylase Shigella flexneri
Q9CM50 8.89e-114 330 66 0 229 3 cobB NAD-dependent protein deacylase Pasteurella multocida (strain Pm70)
Q7MKT7 2.75e-112 327 65 0 232 3 cobB NAD-dependent protein deacylase Vibrio vulnificus (strain YJ016)
Q8D9J9 2.94e-112 327 64 0 235 3 cobB NAD-dependent protein deacylase Vibrio vulnificus (strain CMCP6)
Q87PH8 1.07e-109 320 65 0 229 1 cobB NAD-dependent protein deacylase Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)
Q9KRX4 1.23e-106 312 63 0 229 3 cobB NAD-dependent protein deacylase Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Q4Q2Y6 9.98e-90 270 56 2 233 3 SIR2rp3 NAD-dependent protein deacylase SIR2rp3 Leishmania major
Q8EFN2 1.46e-89 269 59 0 229 3 cobB NAD-dependent protein deacylase Shewanella oneidensis (strain ATCC 700550 / JCM 31522 / CIP 106686 / LMG 19005 / NCIMB 14063 / MR-1)
Q6MJJ2 1.34e-87 264 56 1 229 3 cobB NAD-dependent protein deacylase Bdellovibrio bacteriovorus (strain ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100)
Q584D5 2.62e-85 258 53 2 230 3 SIR2rp3 NAD-dependent protein deacylase SIR2rp3 Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Q9A2S6 7.23e-83 252 53 2 235 3 cobB NAD-dependent protein deacylase Caulobacter vibrioides (strain ATCC 19089 / CIP 103742 / CB 15)
Q7UFQ9 1.94e-76 236 51 3 238 3 cobB NAD-dependent protein deacylase Rhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1)
Q8U1Q1 4.92e-54 179 39 6 239 3 cobB NAD-dependent protein deacylase Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
O58669 4.34e-52 174 37 6 238 3 cobB NAD-dependent protein deacylase Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Q9ZAB8 1.16e-51 171 48 4 192 3 cobB NAD-dependent protein deacylase Aggregatibacter actinomycetemcomitans
O25849 1.54e-51 171 49 4 193 3 cobB NAD-dependent protein deacylase Helicobacter pylori (strain ATCC 700392 / 26695)
Q8A3H9 4.19e-51 171 49 3 189 3 cobB NAD-dependent protein deacylase Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50)
O67919 5.18e-51 171 44 7 208 3 cobB NAD-dependent protein deacylase Aquifex aeolicus (strain VF5)
Q72RR0 2.49e-50 169 39 6 239 3 cobB NAD-dependent protein deacylase Leptospira interrogans serogroup Icterohaemorrhagiae serovar copenhageni (strain Fiocruz L1-130)
Q5JG47 2.91e-50 169 39 6 237 3 cobB NAD-dependent protein deacylase Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
Q8F3Z6 4.09e-50 168 39 6 239 3 cobB NAD-dependent protein deacylase Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)
Q9ZJW8 3.09e-49 166 49 4 188 3 cobB NAD-dependent protein deacylase Helicobacter pylori (strain J99 / ATCC 700824)
Q8ZT00 4.32e-49 166 41 6 230 3 cobB2 NAD-dependent protein deacylase 2 Pyrobaculum aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630 / CIP 104966 / NBRC 100827 / IM2)
Q72IV5 7.74e-49 165 44 5 210 3 cobB NAD-dependent protein deacylase Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27)
E2RDZ6 1.1e-48 167 38 5 249 3 SIRT5 NAD-dependent protein deacylase sirtuin-5, mitochondrial Canis lupus familiaris
Q9UZE7 2.57e-48 164 39 7 236 3 cobB NAD-dependent protein deacylase Pyrococcus abyssi (strain GE5 / Orsay)
Q5SIH7 9.9e-48 162 43 5 210 3 cobB NAD-dependent protein deacylase Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)
Q8TWG0 3.73e-47 161 44 9 211 3 cobB NAD-dependent protein deacylase Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)
Q6DHI5 8.36e-47 162 37 6 248 1 sirt5 NAD-dependent protein deacylase sirtuin-5, mitochondrial Danio rerio
Q3ZBQ0 1.1e-46 161 37 5 249 2 SIRT5 NAD-dependent protein deacylase sirtuin-5, mitochondrial Bos taurus
O28597 1.46e-46 159 40 6 232 1 cobB1 NAD-dependent protein deacylase 1 Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16)
O30124 2.93e-46 159 39 7 234 1 cobB2 NAD-dependent protein deacylase 2 Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16)
C6A243 1.44e-45 157 37 6 244 3 cobB NAD-dependent protein deacylase Thermococcus sibiricus (strain DSM 12597 / MM 739)
Q8Y015 1.77e-45 156 41 7 226 3 cobB NAD-dependent protein deacylase Ralstonia nicotianae (strain ATCC BAA-1114 / GMI1000)
Q8K2C6 2.26e-45 158 35 5 251 1 Sirt5 NAD-dependent protein deacylase sirtuin-5, mitochondrial Mus musculus
Q5HZN8 3.53e-45 157 37 6 248 2 sirt5-a NAD-dependent protein deacylase sirtuin-5A, mitochondrial Xenopus laevis
Q5HU51 1.47e-44 154 36 3 212 3 cobB NAD-dependent protein deacylase Campylobacter jejuni (strain RM1221)
Q9JN05 2.86e-44 153 38 3 202 3 cobB NAD-dependent protein deacylase Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)
Q8R9N6 2.97e-44 153 43 6 203 3 cobB1 NAD-dependent protein deacylase 1 Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4)
F7DKV7 3.65e-44 155 35 5 251 3 sirt5 NAD-dependent protein deacylase sirtuin-5, mitochondrial Xenopus tropicalis
E1BRE2 7.37e-44 154 35 5 248 3 SIRT5 NAD-dependent protein deacylase sirtuin-5, mitochondrial Gallus gallus
E9GD30 1.85e-43 152 35 7 265 3 DAPPUDRAFT_195469 NAD-dependent protein deacylase Daphnia pulex
F7EZ75 3.54e-43 152 36 5 249 3 SIRT5 NAD-dependent protein deacylase sirtuin-5, mitochondrial Macaca mulatta
Q5R6G3 3.73e-43 152 36 5 249 2 SIRT5 NAD-dependent protein deacylase sirtuin-5, mitochondrial Pongo abelii
Q9NXA8 8.03e-43 151 36 5 249 1 SIRT5 NAD-dependent protein deacylase sirtuin-5, mitochondrial Homo sapiens
Q68FX9 1.4e-42 151 35 5 249 2 Sirt5 NAD-dependent protein deacylase sirtuin-5, mitochondrial Rattus norvegicus
Q68F47 4.68e-42 149 36 5 248 2 sirt5-b NAD-dependent protein deacylase sirtuin-5B, mitochondrial Xenopus laevis
Q9RYD4 9.89e-42 147 42 7 214 3 cobB NAD-dependent protein deacylase Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / CCUG 27074 / LMG 4051 / NBRC 15346 / NCIMB 9279 / VKM B-1422 / R1)
Q9YB13 1.87e-41 146 40 5 205 3 cobB NAD-dependent protein deacylase Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)
Q9I4L0 1.42e-39 141 41 7 239 3 cobB1 NAD-dependent protein deacylase 1 Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Q88BY5 2.23e-39 141 36 8 241 3 cobB NAD-dependent protein deacylase Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440)
A0R2N3 1.95e-37 135 35 8 248 1 sir2 NAD-dependent protein deacylase Sir2 Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)
Q73WM7 3.63e-37 135 36 8 245 3 cobB NAD-dependent protein deacylase Mycolicibacterium paratuberculosis (strain ATCC BAA-968 / K-10)
A8NWP2 2.18e-36 134 35 7 246 3 CC1G_00083 NAD-dependent protein deacylase Coprinopsis cinerea (strain Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003)
A9SDL4 5.72e-36 134 35 8 240 3 SRT1505 NAD-dependent protein deacylase Physcomitrium patens
A0QC96 1.43e-35 130 36 8 242 3 cobB2 NAD-dependent protein deacylase 2 Mycobacterium avium (strain 104)
Q7VIN2 1.79e-35 131 34 6 251 3 cobB NAD-dependent protein deacylase Helicobacter hepaticus (strain ATCC 51449 / 3B1)
Q9CBW6 1.18e-34 128 35 9 245 3 cobB NAD-dependent protein deacylase Mycobacterium leprae (strain TN)
P9WGG3 1.26e-34 128 34 6 241 1 cobB NAD-dependent protein deacylase Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
P9WGG2 1.26e-34 128 34 6 241 3 cobB NAD-dependent protein deacylase Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
A5U1J9 1.26e-34 128 34 6 241 1 cobB NAD-dependent protein deacylase Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra)
P66814 1.26e-34 128 34 6 241 3 cobB NAD-dependent protein deacylase Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
Q87W79 4.08e-34 127 36 7 246 3 cobB4 NAD-dependent protein deacylase 4 Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)
Q8FRV5 6.67e-34 127 34 7 240 3 cobB2 NAD-dependent protein deacylase 2 Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395)
F7D4X9 8.92e-34 128 33 7 274 3 SIRT5 NAD-dependent protein deacylase sirtuin-5, mitochondrial Monodelphis domestica
Q88A13 9.29e-34 125 36 7 233 3 cobB1 NAD-dependent protein deacylase 1 Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)
Q97VX5 7.27e-33 124 36 7 214 1 cobB NAD-dependent protein deacetylase Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
A0A0J9UVG7 8e-33 125 30 11 325 1 SIR5 NAD-dependent protein deacylase SIR5 Fusarium oxysporum f. sp. lycopersici (strain 4287 / CBS 123668 / FGSC 9935 / NRRL 34936)
O07595 7.33e-31 119 33 6 241 3 cobB NAD-dependent protein deacetylase Bacillus subtilis (strain 168)
Q607X6 1.13e-30 118 38 8 239 3 cobB NAD-dependent protein deacylase Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath)
A9A0B2 1.84e-30 118 32 8 264 3 cobB NAD-dependent protein deacylase Desulfosudis oleivorans (strain DSM 6200 / JCM 39069 / Hxd3)
Q974M6 3.94e-30 117 34 6 213 3 cobB NAD-dependent protein deacetylase Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)
Q9KEE5 4.55e-30 116 36 5 202 3 cobB NAD-dependent protein deacetylase Halalkalibacterium halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)
Q5L014 1.61e-29 115 37 9 231 3 cobB1 NAD-dependent protein deacetylase 1 Geobacillus kaustophilus (strain HTA426)
Q5WKC8 3.16e-29 114 36 5 212 3 cobB NAD-dependent protein deacetylase Shouchella clausii (strain KSM-K16)
Q7P1B9 3.21e-29 114 33 4 218 3 cobB NAD-dependent protein deacetylase Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / CCUG 213 / NBRC 12614 / NCIMB 9131 / NCTC 9757 / MK)
Q5AI90 4.52e-29 115 28 11 292 3 CAALFM_C102740CA NAD-dependent protein deacylase Candida albicans (strain SC5314 / ATCC MYA-2876)
Q4JBN2 8.13e-29 113 37 5 185 3 cobB NAD-dependent protein deacetylase Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)
A8MBU4 1.33e-28 113 35 8 243 3 cobB NAD-dependent protein deacetylase Caldivirga maquilingensis (strain ATCC 700844 / DSM 13496 / JCM 10307 / IC-167)
Q8NSM4 1.57e-28 112 31 7 245 3 cobB NAD-dependent protein deacylase Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / BCRC 11384 / CCUG 27702 / LMG 3730 / NBRC 12168 / NCIMB 10025 / NRRL B-2784 / 534)
Q8ZU41 1.7e-28 112 35 7 233 3 cobB1 NAD-dependent protein deacetylase 1 Pyrobaculum aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630 / CIP 104966 / NBRC 100827 / IM2)
Q81NT6 2.64e-27 109 34 5 225 3 cobB NAD-dependent protein deacetylase Bacillus anthracis
Q639M6 5.3e-27 108 34 4 223 3 cobB NAD-dependent protein deacetylase Bacillus cereus (strain ZK / E33L)
Q81BT4 7.17e-27 108 34 5 224 3 cobB NAD-dependent protein deacetylase Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NCTC 2599 / NRRL B-3711)
Q735N7 9.27e-27 107 33 4 223 3 cobB NAD-dependent protein deacetylase Bacillus cereus (strain ATCC 10987 / NRS 248)
Q8ELR0 1.02e-26 107 35 6 205 3 cobB NAD-dependent protein deacetylase Oceanobacillus iheyensis (strain DSM 14371 / CIP 107618 / JCM 11309 / KCTC 3954 / HTE831)
B5YJW3 1.04e-26 108 36 9 235 3 cobB NAD-dependent protein deacetylase Thermodesulfovibrio yellowstonii (strain ATCC 51303 / DSM 11347 / YP87)
Q8XNS6 1.91e-26 107 32 6 230 3 cobB NAD-dependent protein deacetylase Clostridium perfringens (strain 13 / Type A)
Q6HH09 8.5e-26 105 33 4 223 3 cobB NAD-dependent protein deacetylase Bacillus thuringiensis subsp. konkukian (strain 97-27)
Q927A7 2.06e-25 103 34 5 184 3 cobB NAD-dependent protein deacetylase Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262)
Q6A5T5 3.32e-25 103 35 7 211 3 cobB NAD-dependent protein deacetylase Cutibacterium acnes (strain DSM 16379 / KPA171202)
Q8CJM9 6.45e-25 102 31 7 239 3 cobB2 NAD-dependent protein deacetylase 2 Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Q71W25 2.68e-24 100 33 6 184 3 cobB NAD-dependent protein deacetylase Listeria monocytogenes serotype 4b (strain F2365)
Q8R984 7.96e-24 100 34 9 210 3 cobB2 NAD-dependent protein deacetylase 2 Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4)
Q8Y3U2 1.54e-23 99 32 5 185 3 cobB NAD-dependent protein deacetylase Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)
Q899G3 2.93e-23 98 32 7 201 3 cobB NAD-dependent protein deacetylase Clostridium tetani (strain Massachusetts / E88)
Q9WYW0 4.97e-23 98 35 9 207 1 cobB NAD-dependent protein deacetylase Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)
Q1JQC6 5.02e-23 99 32 9 240 2 SIRT4 NAD-dependent protein lipoamidase sirtuin-4, mitochondrial Bos taurus
Q73KE1 5.17e-23 98 31 5 212 3 cobB NAD-dependent protein deacetylase Treponema denticola (strain ATCC 35405 / DSM 14222 / CIP 103919 / JCM 8153 / KCTC 15104)
Q88ZA0 9.84e-23 97 33 6 211 3 cobB NAD-dependent protein deacetylase Lactiplantibacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1)
Q8REC3 1.1e-22 97 30 8 206 3 cobB NAD-dependent protein deacetylase Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / DSM 15643 / BCRC 10681 / CIP 101130 / JCM 8532 / KCTC 2640 / LMG 13131 / VPI 4355)
Q5KZE8 1.22e-22 97 33 8 241 3 cobB2 NAD-dependent protein deacetylase 2 Geobacillus kaustophilus (strain HTA426)
Q8CNF4 2.51e-22 96 36 7 198 3 cobB NAD-dependent protein deacetylase Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200)
Q6N6U0 2.55e-22 96 34 7 228 3 cobB NAD-dependent protein deacetylase Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)
Q5HM33 2.76e-22 95 36 7 198 3 cobB NAD-dependent protein deacetylase Staphylococcus epidermidis (strain ATCC 35984 / DSM 28319 / BCRC 17069 / CCUG 31568 / BM 3577 / RP62A)
Q5V4Q5 5.07e-22 95 31 10 247 3 cobB NAD-dependent protein deacetylase Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)
Q8R216 6.68e-22 96 30 9 240 1 Sirt4 NAD-dependent protein lipoamidase sirtuin-4, mitochondrial Mus musculus
Q97MB4 7.8e-22 94 32 7 196 3 cobB NAD-dependent protein deacetylase Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / IAM 19013 / LMG 5710 / NBRC 13948 / NRRL B-527 / VKM B-1787 / 2291 / W)
Q839C6 2.2e-21 93 32 6 200 3 cobB NAD-dependent protein deacetylase Enterococcus faecalis (strain ATCC 700802 / V583)
Q6GEN2 3.4e-21 93 36 7 194 3 cobB NAD-dependent protein deacetylase Staphylococcus aureus (strain MRSA252)
Q5HE07 9.38e-21 92 35 7 194 3 cobB NAD-dependent protein deacetylase Staphylococcus aureus (strain COL)
Q8IE47 9.68e-21 92 27 5 221 1 Sir2A NAD-dependent protein deacylase Sir2A Plasmodium falciparum (isolate 3D7)
Q53700 1.24e-20 91 35 7 194 3 cobB NAD-dependent protein deacetylase Staphylococcus aureus (strain NCTC 8325 / PS 47)
P66816 1.67e-20 91 35 7 194 3 cobB NAD-dependent protein deacetylase Staphylococcus aureus (strain N315)
P66815 1.67e-20 91 35 7 194 1 cobB NAD-dependent protein deacetylase Staphylococcus aureus (strain Mu50 / ATCC 700699)
Q89LY4 2.15e-20 91 33 9 223 3 cobB1 NAD-dependent protein deacetylase 1 Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110)
Q8NVC8 3.41e-20 90 35 7 194 3 cobB NAD-dependent protein deacetylase Staphylococcus aureus (strain MW2)
Q6G7B7 3.41e-20 90 35 7 194 3 cobB NAD-dependent protein deacetylase Staphylococcus aureus (strain MSSA476)
Q67KQ0 8.5e-20 89 34 8 211 3 cobB NAD-dependent protein deacetylase Symbiobacterium thermophilum (strain DSM 24528 / JCM 14929 / IAM 14863 / T)
Q9Y6E7 8.6e-20 90 30 9 240 1 SIRT4 NAD-dependent protein lipoamidase sirtuin-4, mitochondrial Homo sapiens
Q9I4E1 1.74e-18 85 29 9 247 3 cobB2 NAD-dependent protein deacylase 2 Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
A0A0G2JZ79 2.19e-17 85 33 10 218 3 Sirt1 NAD-dependent protein deacetylase sirtuin-1 Rattus norvegicus
Q885X7 4.67e-17 82 30 13 233 3 cobB2 NAD-dependent protein deacylase 2 Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)
Q923E4 1.19e-16 83 33 11 214 1 Sirt1 NAD-dependent protein deacetylase sirtuin-1 Mus musculus
Q96EB6 1.37e-16 83 33 11 214 1 SIRT1 NAD-dependent protein deacetylase sirtuin-1 Homo sapiens
Q20480 1.72e-16 80 27 11 248 1 sir-2.2 NAD-dependent protein deacylase sir-2.2 Caenorhabditis elegans
C1DBX3 2.73e-16 79 30 5 230 3 cobB NAD-dependent protein deacetylase Laribacter hongkongensis (strain HLHK9)
Q8PQK3 3.43e-15 77 30 9 235 3 cobB NAD-dependent protein deacetylase Xanthomonas axonopodis pv. citri (strain 306)
Q21921 4.67e-15 78 31 10 213 1 sir-2.1 NAD-dependent protein deacetylase sir-2.1 Caenorhabditis elegans
Q8FUC8 6.74e-15 76 27 10 265 3 cobB1 NAD-dependent protein deacetylase 1 Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395)
Q54LF0 3.14e-14 76 30 10 220 2 sir2B NAD-dependent deacetylase sir2B Dictyostelium discoideum
A9UVV1 3.99e-14 74 27 10 269 3 15984 NAD-dependent protein deacylase SIR4 Monosiga brevicollis
O59923 4.51e-14 75 31 12 220 1 SIR2 NAD-dependent histone deacetylase SIR2 Candida albicans (strain SC5314 / ATCC MYA-2876)
Q9VK34 5.17e-14 75 30 10 224 1 Sirt1 NAD-dependent histone deacetylase sirtuin-1 Drosophila melanogaster
Q8PDM9 1.18e-13 73 29 9 237 3 cobB NAD-dependent protein deacetylase Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)
Q4UZX0 1.18e-13 73 29 9 237 3 cobB NAD-dependent protein deacetylase Xanthomonas campestris pv. campestris (strain 8004)
Q60L58 1.62e-13 73 29 10 232 3 sir-2.1 NAD-dependent protein deacetylase sir-2.1 Caenorhabditis briggsae
B0RM75 1.92e-13 72 29 9 237 3 cobB NAD-dependent protein deacetylase Xanthomonas campestris pv. campestris (strain B100)
A0QDH4 2.13e-13 72 27 8 237 3 cobB1 NAD-dependent protein deacetylase 1 Mycobacterium avium (strain 104)
Q20481 2.35e-13 72 33 7 139 1 sir-2.3 NAD-dependent protein deacylase sir-2.3 Caenorhabditis elegans
Q89EA6 2.41e-13 72 30 9 223 3 cobB2 NAD-dependent protein deacetylase 2 Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110)
Q54P49 2.65e-13 73 32 10 212 2 sir2C NAD-dependent deacetylase sir2C Dictyostelium discoideum
Q55DB0 1.57e-12 70 25 11 229 2 sir2E NAD-dependent deacetylase sir2E Dictyostelium discoideum
Q94AQ6 3.2e-12 69 26 12 256 1 SRT2 NAD-dependent protein deacylase SRT2 Arabidopsis thaliana
F4P804 4.5e-12 68 26 11 279 3 BATDEDRAFT_20316 NAD-dependent protein deacylase SIR4 Batrachochytrium dendrobatidis (strain JAM81 / FGSC 10211)
A0A250YGJ5 8.47e-12 68 27 8 234 1 SIRT6 NAD-dependent protein deacylase sirtuin-6 Castor canadensis
Q8IRR5 1.03e-11 67 37 5 120 2 Sirt4 NAD-dependent protein deacylase Sirt4 Drosophila melanogaster
Q54QE6 2.13e-11 67 27 12 237 2 sir2A NAD-dependent deacetylase sir2A Dictyostelium discoideum
Q8N6T7 3.72e-11 66 27 8 234 1 SIRT6 NAD-dependent protein deacylase sirtuin-6 Homo sapiens
Q9NTG7 4.23e-11 66 29 11 207 1 SIRT3 NAD-dependent protein deacetylase sirtuin-3, mitochondrial Homo sapiens
A0A2K5TU92 6.1e-11 65 27 8 234 1 SIRT6 NAD-dependent protein deacylase sirtuin-6 Macaca fascicularis
P59941 9.2e-11 65 26 8 234 1 Sirt6 NAD-dependent protein deacylase sirtuin-6 Mus musculus
Q8R104 9.38e-11 65 30 11 206 1 Sirt3 NAD-dependent protein deacetylase sirtuin-3 Mus musculus
Q7VX46 9.84e-11 64 27 6 257 3 cobB NAD-dependent protein deacetylase Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)
Q7WLE5 1.19e-10 64 27 6 257 3 cobB NAD-dependent protein deacetylase Bordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50)
Q9FE17 1.37e-10 65 25 10 268 1 SRT1 NAD-dependent protein deacetylase SRT1 Arabidopsis thaliana
P0CS88 1.88e-10 64 32 9 198 3 AN11873 NAD-dependent protein deacetylase hst2-2 Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)
Q9I7I7 4.08e-10 63 30 11 205 3 Sirt2 NAD-dependent protein deacetylase Sirt2 Drosophila melanogaster
Q882K4 6.46e-10 62 26 8 268 3 cobB3 NAD-dependent protein deacetylase 3 Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)
Q57V41 7.55e-10 62 28 7 193 1 SIR2rp1 NAD-dependent protein deacetylase SIR2rp1 Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Q757M7 1.41e-09 62 25 15 306 3 SIR2 NAD-dependent histone deacetylase SIR2 Eremothecium gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
Q54GV7 1.96e-09 61 30 11 200 2 sir2D NAD-dependent deacetylase sir2D Dictyostelium discoideum
Q5AW69 1.97e-09 61 30 9 200 3 AN7461 NAD-dependent protein deacetylase hst2-1 Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)
Q8VDQ8 3.34e-09 60 28 12 215 1 Sirt2 NAD-dependent protein deacetylase sirtuin-2 Mus musculus
P33294 4.66e-09 60 28 8 170 3 SIR2 NAD-dependent histone deacetylase SIR2 Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
Q7XWV4 6.16e-09 60 24 9 259 1 SRT1 NAD-dependent protein deacetylase SRT1 Oryza sativa subsp. japonica
Q6FWI7 6.76e-09 60 25 12 271 3 SIR2 NAD-dependent histone deacetylase SIR2 Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138)
B8ARK7 6.88e-09 59 24 9 259 1 SRT1 NAD-dependent protein deacetylase SRT1 Oryza sativa subsp. indica
Q9RL35 7.54e-09 59 31 4 121 3 cobB1 NAD-dependent protein deacetylase 1 Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Q57YZ9 1.95e-08 57 27 11 244 3 SIR2rp2 NAD-dependent protein deacylase SIR2rp2 Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Q9USN7 2.45e-08 57 30 13 206 3 hst2 NAD-dependent protein deacetylase hst2 Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Q25337 2.58e-08 57 30 11 209 2 SIR2rp1 NAD-dependent protein deacetylase SIR2rp1 Leishmania major
P06700 2.94e-08 58 25 14 302 1 SIR2 NAD-dependent histone deacetylase SIR2 Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Q5RJQ4 3.13e-08 57 27 12 215 1 Sirt2 NAD-dependent protein deacetylase sirtuin-2 Rattus norvegicus
Q9VH08 4.1e-08 57 24 9 250 1 Sirt6 NAD-dependent protein deacetylase Sirt6 Drosophila melanogaster
Q5RBF1 8.03e-08 56 26 12 213 1 SIRT2 NAD-dependent protein deacetylase sirtuin-2 Pongo abelii
P53685 9.96e-08 56 26 10 229 1 HST1 NAD-dependent protein deacetylase HST1 Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
P53686 1.16e-07 55 28 12 236 1 HST2 NAD-dependent protein deacetylase HST2 Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Q8IXJ6 2.19e-07 55 26 12 213 1 SIRT2 NAD-dependent protein deacetylase sirtuin-2 Homo sapiens
O94640 2.38e-07 55 25 10 238 1 sir2 NAD-dependent histone deacetylase sir2 Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Q4R834 2.67e-07 54 26 12 213 2 SIRT2 NAD-dependent protein deacetylase sirtuin-2 Macaca fascicularis
Q5A985 1.71e-06 52 28 11 199 3 HST2 NAD-dependent protein deacetylase HST2 Candida albicans (strain SC5314 / ATCC MYA-2876)
C8V3W5 1.97e-06 52 25 10 240 3 AN10449 NAD-dependent protein deacetylase hst1 Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)
Q5BE04 1.16e-05 50 27 14 277 3 AN1226 NAD-dependent protein deacetylase hst4 Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)
Q7ZVK3 1.24e-05 49 27 10 203 1 sirt2 NAD-dependent protein deacetylase sirtuin-2 Danio rerio
Q9NRC8 1.61e-05 49 27 9 201 1 SIRT7 NAD-dependent protein deacetylase sirtuin-7 Homo sapiens
Q8BKJ9 2.63e-05 48 27 10 204 1 Sirt7 NAD-dependent protein deacetylase sirtuin-7 Mus musculus
Q0P595 2.65e-05 48 26 9 201 2 SIRT7 NAD-dependent protein deacetylase sirtuin-7 Bos taurus
Q9UR39 3.13e-05 48 25 9 252 2 hst4 NAD-dependent protein deacetylase hst4 Schizosaccharomyces pombe (strain 972 / ATCC 24843)
B2RZ55 0.000224 45 25 10 205 2 Sirt7 NAD-dependent protein deacetylase sirtuin-7 Rattus norvegicus
Q5AQ47 0.000642 44 30 6 138 3 HST1 NAD-dependent protein deacetylase HST1 Candida albicans (strain SC5314 / ATCC MYA-2876)

  • Number of RefSeq hits:

General

Source Morganella morganii S4
Locus tag NLDBIP_15950
Feature type CDS
Gene cobB
Product Sir2 family NAD+-dependent deacetylase
Location 49471 - 50337 (strand: -1)
Length 867 (nucleotides) / 288 (amino acids)

Contig

Accession ZDB_532
Length 116685 nucleotides
Topology linear
Plasmid False

Orthology

Orthogroup group_1947
Orthogroup size 7
N. genomes 7

Actions

Genomic region

Domains

PF02146 Sir2 family

COG entry Annotation(s)

ID Function(s) descr. Function(s) cat. Description
COG0846 Posttranslational modification, protein turnover, chaperones (O) O NAD-dependent protein deacetylase, SIR2 family

Kegg Ortholog Annotation(s)

KO Description Pathways Modules
K12410 NAD-dependent protein deacetylase/lipoamidase [EC:2.3.1.286 2.3.1.313] Nicotinate and nicotinamide metabolism
Metabolic pathways		 -

Protein Sequence

MNKGRIMRRTHRLRKLRKQRRILRQRFHLRFFYRDKWMAGKMDQFKPKIVVLTGAGISAESGIRTFRSEDGLWEEHNIEDVATPEGYARNPRLVQQFYNDRRRQLQSPDVQPNPAHLALAELEQVLGDNFLLVTQNIDNLHERAGSQRIIHMHGELLKIRCAMSGQVQSCTGDLSADERCHCCQFPSPLRPHIVWFGEMPFGMDEIYQALNDADIFIAIGTSGHVYPAAGFVHEARLCGAHTVELNLEPSKVQSEFEECHYGPAGQVVPEYVRQLLAQINNTKSDLTQ

Flanking regions ( +/- flanking 50bp)

ATGATTTTTGAATCCGAAGTGCGGATGCATTACCCTGAACGGAGACAGTGATGAACAAAGGCCGGATTATGCGCAGAACGCACCGATTAAGAAAGTTACGCAAACAGCGGCGGATCCTGCGCCAGCGTTTTCACTTACGCTTTTTCTATCGCGATAAATGGATGGCCGGAAAAATGGATCAGTTTAAACCTAAAATTGTTGTGCTGACCGGCGCGGGTATCTCCGCCGAGTCCGGGATCCGGACATTCCGTTCGGAAGACGGGCTGTGGGAAGAGCACAACATCGAGGATGTGGCGACGCCGGAAGGCTATGCCCGCAATCCGCGTCTGGTGCAGCAGTTTTACAATGACCGCCGCCGCCAGTTACAGTCCCCTGACGTGCAGCCGAACCCGGCACATCTCGCCCTGGCGGAGCTGGAACAGGTGCTGGGGGATAACTTCCTGCTGGTCACCCAGAATATTGATAACCTGCATGAGCGGGCAGGTAGTCAGCGGATTATTCATATGCACGGCGAGTTGCTGAAAATTCGCTGTGCGATGTCCGGACAGGTTCAGTCGTGCACCGGTGACCTGTCAGCGGATGAGCGCTGCCACTGTTGTCAGTTCCCGTCACCGCTGCGGCCGCATATTGTCTGGTTCGGTGAAATGCCGTTCGGCATGGATGAAATCTATCAGGCACTGAATGATGCGGATATCTTTATCGCCATCGGTACCTCCGGGCATGTCTATCCGGCGGCCGGGTTTGTCCATGAGGCACGGCTGTGCGGGGCACATACAGTGGAACTCAATCTGGAACCGAGTAAGGTGCAGAGTGAGTTTGAGGAGTGTCACTACGGTCCTGCCGGGCAGGTGGTGCCGGAGTATGTCCGTCAGCTGCTGGCGCAGATTAACAACACTAAATCTGATTTGACGCAATAACTCAATTTATGTTTCCCCGATAATAAGAAATCAATGTTATTGGGGGAACA