Homologs in group_2494

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5 homologs were identified in 5 genomes with OrthoFinder.
The following table displays the locus tag of each homolog, the organism to which it belongs, the gene name and product.

Locus tag Identity Source Gene Product
FBDBKF_01710 FBDBKF_01710 100.0 Morganella morganii S1 adaB DNA repair enzyme Ada (O6-methylguanine-DNA--protein-cysteine methyltransferase)
EHELCC_02180 EHELCC_02180 100.0 Morganella morganii S2 adaB DNA repair enzyme Ada (O6-methylguanine-DNA--protein-cysteine methyltransferase)
NLDBIP_01280 NLDBIP_01280 100.0 Morganella morganii S4 adaB DNA repair enzyme Ada (O6-methylguanine-DNA--protein-cysteine methyltransferase)
LHKJJB_00755 LHKJJB_00755 100.0 Morganella morganii S3 adaB DNA repair enzyme Ada (O6-methylguanine-DNA--protein-cysteine methyltransferase)
F4V73_RS04040 F4V73_RS04040 75.4 Morganella psychrotolerans - methylated-DNA--[protein]-cysteine S-methyltransferase

Distribution of the homologs in the orthogroup group_2494

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Number of homologs in each genome (first column) and amino-acid identity of the closest homolog (second column).

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Phylogeny of the RefSeq best hits of group_2494

Swissprot accession Eval Score ID (%) N gaps Alignment length Annot score Gene Description Organism
P11742 1.22e-39 135 44 4 168 1 ogt Methylated-DNA--protein-cysteine methyltransferase, constitutive Bacillus subtilis (strain 168)
P0A2U0 2.58e-35 124 56 1 105 3 ogt Methylated-DNA--protein-cysteine methyltransferase Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
P0A2U1 2.58e-35 124 56 1 105 3 ogt Methylated-DNA--protein-cysteine methyltransferase Salmonella typhi
P0AFH1 4.9e-35 123 54 1 105 3 ogt Methylated-DNA--protein-cysteine methyltransferase Shigella flexneri
P0AFH0 4.9e-35 123 54 1 105 1 ogt Methylated-DNA--protein-cysteine methyltransferase Escherichia coli (strain K12)
Q8TI34 4.71e-34 120 38 2 165 3 ogt Methylated-DNA--protein-cysteine methyltransferase Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)
Q46EW4 5.68e-34 120 39 2 155 3 ogt Methylated-DNA--protein-cysteine methyltransferase Methanosarcina barkeri (strain Fusaro / DSM 804)
P9WJW5 2.14e-33 119 54 0 103 1 ogt Methylated-DNA--protein-cysteine methyltransferase Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
P9WJW4 2.14e-33 119 54 0 103 3 ogt Methylated-DNA--protein-cysteine methyltransferase Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
P0A697 2.14e-33 119 54 0 103 3 ogt Methylated-DNA--protein-cysteine methyltransferase Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
P52982 1.61e-32 117 51 0 104 3 ogt Methylated-DNA--protein-cysteine methyltransferase Mycobacterium leprae (strain TN)
Q5UNU9 2.36e-32 115 51 2 105 3 MGMT Probable methylated-DNA--protein-cysteine methyltransferase Acanthamoeba polyphaga mimivirus
Q8PY44 2.88e-32 115 40 2 149 3 ogt Methylated-DNA--protein-cysteine methyltransferase Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88)
Q9ZET8 3.01e-32 116 50 0 109 3 ogt Methylated-DNA--protein-cysteine methyltransferase Mycolicibacterium paratuberculosis (strain ATCC BAA-968 / K-10)
P19220 5.87e-32 115 41 1 149 1 adaB Methylated-DNA--protein-cysteine methyltransferase, inducible Bacillus subtilis (strain 168)
P06134 2.46e-26 105 35 2 158 1 ada Bifunctional transcriptional activator/DNA repair enzyme Ada Escherichia coli (strain K12)
P44687 3.18e-26 101 46 1 102 3 ogt Methylated-DNA--protein-cysteine methyltransferase Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
P26189 1.5e-25 103 35 3 160 3 ada Regulatory protein ada Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
P26188 3.34e-21 88 49 0 85 1 MGT1 Methylated-DNA--protein-cysteine methyltransferase Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Q6CPW2 4.46e-21 88 44 0 86 3 MGT1 Methylated-DNA--protein-cysteine methyltransferase Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
A6ZXD3 1.63e-20 86 48 0 85 3 MGT1 Methylated-DNA--protein-cysteine methyltransferase Saccharomyces cerevisiae (strain YJM789)
A3LZM4 1.26e-19 84 45 1 85 3 MGT1 Methylated-DNA--protein-cysteine methyltransferase Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)
P16455 2.72e-19 84 34 4 167 1 MGMT Methylated-DNA--protein-cysteine methyltransferase Homo sapiens
Q6TDU1 3.66e-18 81 43 2 108 2 MGMT Methylated-DNA--protein-cysteine methyltransferase Canis lupus familiaris
Q5A0Y8 1.06e-17 79 46 1 84 3 MGT1 Methylated-DNA--protein-cysteine methyltransferase Candida albicans (strain SC5314 / ATCC MYA-2876)
C3N9B4 4.04e-17 77 31 6 167 3 ogt Methylated-DNA--protein-cysteine methyltransferase Sulfolobus islandicus (strain Y.G.57.14 / Yellowstone #1)
C3MUC6 4.04e-17 77 31 6 167 3 ogt Methylated-DNA--protein-cysteine methyltransferase Sulfolobus islandicus (strain M.14.25 / Kamchatka #1)
C3MKT6 4.04e-17 77 31 6 167 3 ogt Methylated-DNA--protein-cysteine methyltransferase Sulfolobus islandicus (strain L.S.2.15 / Lassen #1)
C4KKV8 4.04e-17 77 31 6 167 3 ogt Methylated-DNA--protein-cysteine methyltransferase Sulfolobus islandicus (strain M.16.4 / Kamchatka #3)
Q97VW7 4.04e-17 77 31 6 167 1 ogt Methylated-DNA--protein-cysteine methyltransferase Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
P26186 4.64e-17 78 33 4 168 2 MGMT Methylated-DNA--protein-cysteine methyltransferase Cricetulus griseus
C3N1B4 5.87e-17 76 31 6 167 3 ogt Methylated-DNA--protein-cysteine methyltransferase Sulfolobus islandicus (strain M.16.27)
Q58924 1.06e-16 76 34 4 135 1 ogt Methylated-DNA--protein-cysteine methyltransferase Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
C3NMY2 2.49e-16 74 30 5 166 3 ogt Methylated-DNA--protein-cysteine methyltransferase Sulfolobus islandicus (strain Y.N.15.51 / Yellowstone #2)
P26187 3.01e-16 75 32 4 174 1 Mgmt Methylated-DNA--protein-cysteine methyltransferase Mus musculus
P24528 4.06e-16 75 31 4 176 1 Mgmt Methylated-DNA--protein-cysteine methyltransferase Rattus norvegicus
Q6FNR0 4.3e-16 75 39 0 81 3 MGT1 Methylated-DNA--protein-cysteine methyltransferase Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138)
Q6BVY4 7.4e-16 74 38 1 99 3 MGT1 Methylated-DNA--protein-cysteine methyltransferase Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)
A5E7M8 1.88e-15 73 43 1 82 3 MGT1 Methylated-DNA--protein-cysteine methyltransferase Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239)
A4YH39 1.02e-14 70 38 5 113 3 ogt Methylated-DNA--protein-cysteine methyltransferase Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2)
O27970 3.33e-14 69 39 2 87 3 ogt Methylated-DNA--protein-cysteine methyltransferase Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16)
C9RE37 8.62e-13 65 42 4 85 3 ogt Methylated-DNA--protein-cysteine methyltransferase Methanocaldococcus vulcanius (strain ATCC 700851 / DSM 12094 / M7)
Q973C7 1.73e-11 62 27 5 165 1 ogt Methylated-DNA--protein-cysteine methyltransferase Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)
Q4J9C6 2.61e-11 61 30 6 153 3 ogt Methylated-DNA--protein-cysteine methyltransferase Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)
Q5SI16 3.02e-11 61 41 4 103 1 TTHA1564 DNA base-flipping protein Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)
O26715 4.36e-10 58 42 3 82 3 ogt Methylated-DNA--protein-cysteine methyltransferase Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)
F0LIT8 5.01e-10 58 43 4 89 3 ogt Methylated-DNA--protein-cysteine methyltransferase Thermococcus barophilus (strain DSM 11836 / MP)
O74023 1.12e-09 57 41 3 81 1 ogt Methylated-DNA--protein-cysteine methyltransferase Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
C6A382 1.13e-08 55 41 4 82 3 ogt Methylated-DNA--protein-cysteine methyltransferase Thermococcus sibiricus (strain DSM 12597 / MM 739)
C5A3L5 1.24e-08 55 41 4 82 3 ogt Methylated-DNA--protein-cysteine methyltransferase Thermococcus gammatolerans (strain DSM 15229 / JCM 11827 / EJ3)
O93728 2.23e-08 53 42 2 76 3 ogt Methylated-DNA--protein-cysteine methyltransferase Pyrobaculum aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630 / CIP 104966 / NBRC 100827 / IM2)
Q8TZV2 3.4e-06 48 37 3 81 3 ogt Methylated-DNA--protein-cysteine methyltransferase Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
F4HK38 5.77e-06 47 30 9 152 3 ogt Methylated-DNA--protein-cysteine methyltransferase Pyrococcus sp. (strain NA2)
O59499 6.63e-06 47 33 6 130 3 ogt Methylated-DNA--protein-cysteine methyltransferase Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
P0AFP3 1.89e-05 45 37 2 86 3 atl DNA base-flipping protein Shigella flexneri
P0AFP2 1.89e-05 45 37 2 86 1 atl DNA base-flipping protein Escherichia coli (strain K12)
Q8TZ11 2.35e-05 45 31 3 105 3 ogt Methylated-DNA--protein-cysteine methyltransferase Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)
Q6KZ38 3.04e-05 46 33 0 74 3 PTO1429 Bifunctional methyltransferase/endonuclease Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828 / KAW 2/3)
Q9UTN9 0.000127 42 33 0 62 1 atl1 Alkyltransferase-like protein 1 Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Q9V1N7 0.000401 42 37 2 61 3 ogt Methylated-DNA--protein-cysteine methyltransferase Pyrococcus abyssi (strain GE5 / Orsay)

  • Number of RefSeq hits:

General

Source Morganella morganii S5
Locus tag HKOGLL_00795
Feature type CDS
Gene adaB
Product DNA repair enzyme Ada (O6-methylguanine-DNA--protein-cysteine methyltransferase)
Location 137786 - 138301 (strand: 1)
Length 516 (nucleotides) / 171 (amino acids)

Contig

Accession ZDB_679
Length 398279 nucleotides
Topology linear
Plasmid False

Orthology

Orthogroup group_2494
Orthogroup size 6
N. genomes 6

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Genomic region

Domains

PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain
PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain

COG entry Annotation(s)

ID Function(s) descr. Function(s) cat. Description
COG0350 Replication, recombination and repair (L) L DNA repair enzyme Ada (O6-methylguanine-DNA--protein-cysteine methyltransferase)

Kegg Ortholog Annotation(s)

KO Description Pathways Modules
K00567 methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] - -

Protein Sequence

MIFRTQFSTVLGEMSAAATEQGVCFLEFTEDNRREDTLQLVSSRLKMAVTDGNHPHLALLESQLQDYFAGKRMIFTVPLVLPGTPFQQKVWDALLSVPFGSTVTYSMLAVSLSSPRAVRAVGRANGMNPVSVLVPCHRVTGKNGELTGYAGGTDRKAWLLAHEKQVKGASA

Flanking regions ( +/- flanking 50bp)

AAAGTAAACGGTACACCTGACAGTGATACACGAAAAATAAAGGAATTCTGATGATATTTCGTACACAATTCAGCACGGTACTGGGTGAAATGTCGGCAGCGGCAACAGAGCAGGGTGTTTGTTTTCTGGAATTTACGGAAGACAACCGCCGTGAAGATACCTTACAGCTGGTTTCTTCCCGGCTGAAAATGGCGGTAACAGACGGAAATCATCCTCACCTGGCGTTGCTGGAGTCACAACTGCAGGACTATTTTGCCGGTAAACGGATGATATTTACCGTTCCGCTGGTGCTGCCGGGAACGCCTTTTCAGCAAAAAGTCTGGGATGCATTATTGTCTGTGCCGTTTGGCAGCACCGTTACTTACAGTATGCTGGCGGTGTCATTATCCTCACCGCGCGCTGTCCGGGCTGTCGGGCGGGCCAACGGGATGAATCCGGTTTCCGTGCTGGTACCGTGTCACCGCGTTACCGGCAAAAACGGCGAACTGACCGGCTATGCAGGAGGAACGGACCGCAAAGCCTGGTTACTGGCTCATGAAAAACAGGTTAAAGGAGCATCAGCATGATTTTCTGTAAACGGGTTTATGATGAGGTCGCGGAAAGTGACGGTTACCGG