VFG048941
Help to interpret the results
Three outputs have been generated:
General: this tab contains the description, occurence in the database and other information related to the selected Virulence factor VFG048941
Protein list: lists the 5 occurences of the Virulence factor within the database. The table reports information on each occurence.
Profile: phylogenetic tree annotated with
- the presence of the Virulence factor of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported Virulence factor has been clustered.
Orthogroups are shown in red if they are annotated with that particular Virulence factor in a given genome , in green otherwise, i.e. if there is a discrepency between orthogroup clustering and Virulence factor prediction.
Green homologs (same orthogroup) are not positive hit(s) for the considered Virulence factor.
Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or Virulence factor prediction.
Description
Protein |
NADP-dependent phosphogluconate dehydrogenase |
VF ID |
VF0560 |
Category |
Immune modulation |
Protein ID |
WP_020953355 |
Characteristics |
The Klebsiella polysaccharide capsule is produced through a Wzy-dependent process, for which the synthesis and export machinery are encoded in a single 10-30 kb region of the genome known as the K locus.; 78 distinct capsule phenotypes have been recognized by serological typing, but many isolates are serologically non-typable.; capsular serotypes vary substantially in the degree of serum resistance; K1, K2 and K5 are highly serum resistant and are associated with hypervirulent strains that differ from classical K. pneumoniae in that they commonly cause community-acquired disease. |
Function |
Assisting in evading the host immune system by protecting bacteria from opsonophagocytosis and serum killing |
Vf_category_id |
VFC0258 |
Occurence in the database
VFG048941 is associated with 5 different
proteins
|
The 5 proteins are classified into 1 different orthogroup(s)
|
|
Orthogroup |
Locus |
Start |
Stop |
S. |
Gene |
Product |
Organism |
0 |
group_1249 |
FBDBKF_06870 |
37974 |
39386 |
-1 |
gndA |
NADP-dependent phosphogluconate dehydrogenase |
Morganella morganii S1 |
1 |
group_1249 |
EHELCC_04100 |
146800 |
148212 |
1 |
gndA |
NADP-dependent phosphogluconate dehydrogenase |
Morganella morganii S2 |
2 |
group_1249 |
NLDBIP_04100 |
146596 |
148008 |
1 |
gndA |
NADP-dependent phosphogluconate dehydrogenase |
Morganella morganii S4 |
3 |
group_1249 |
LHKJJB_09930 |
146710 |
148122 |
1 |
gndA |
NADP-dependent phosphogluconate dehydrogenase |
Morganella morganii S3 |
4 |
group_1249 |
HKOGLL_09045 |
42930 |
44342 |
-1 |
gndA |
NADP-dependent phosphogluconate dehydrogenase |
Morganella morganii S5 |