VFG042265
Help to interpret the results
Three outputs have been generated:
General: this result contains the description and frequency of the selected Virulence factors VFG042265, of which KO pathways and KO modules it is part. Additionally, its occurence in the database is reported.
Proteins list: list of occurences of the Virulence factors
within the database. 1 occurences are identified.
The table reports the orthogroup, the organism in which each occurrence has been found, and the locus tag enriched by start and stop position, strand, gene name and product.
Clicking on the Ortohgroup name or locus you will be redirected to further info.
Profiles: Phylogenetic tree annotated with
- the presence of the Virulence factor(s) of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported Virulence factors has been clustered.
In red the Virulence factors with positive hit(s) in the corresponding genome.
In green the discrepencies between orthogroup clustering and Virulence factors prediction.
Green homologs (same orthogroup) are not positive hit(s) for the considered Virulence factors.
Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or Virulence factors prediction.
Description
Protein |
AscN |
VF ID |
VF0479 |
Category |
Effector delivery system |
Protein ID |
AAS91810 |
Characteristics |
Similar to the Yersinia T3SS |
Function |
A needle-like structure, often described as an "injectisome" that can inject effectors directly into the cytoplasm of target cells; five effectors have been described: AexT, AexU, AopP, AopH and AopO; AexT and AexU are bifunctional toxins that contain a GTPase activating domain, allowing the interruption of host cell-signalling pathways and an ADP-ribosylating domain that can disrupt the host cytoskeleton, leading to the induction of apoptosis; AopP (NF-kappaB inhibitor), AopH (tyrosine phosphatase) and AopO (serine/threonine kinase), all are able to interrupt host cell signalling pathways and induce toxicity |
Vf_category_id |
VFC0086 |
Occurence in the database
VFG042265 is associated with 1 different proteins (see tab "Protein list" and "Profile") |
The 1 proteins are classified into 1 different orthogroup(s)
|
# |
Orthogroup |
Locus |
Start |
Stop |
S. |
Gene |
Product |
Organism |
0 |
group_225 |
F4V73_RS08315 |
1723851 |
1725170 |
1 |
|
FliI/YscN family ATPase |
Morganella psychrotolerans |