VFG023778


Help to interpret the results

Three outputs have been generated:
General: this tab contains the description, occurence in the database and other information related to the selected Virulence factor VFG023778
Protein list: lists the 7 occurences of the Virulence factor within the database. The table reports information on each occurence.
Profile: phylogenetic tree annotated with
- the presence of the Virulence factor of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported Virulence factor has been clustered.
Orthogroups are shown in red if they are annotated with that particular Virulence factor in a given genome , in green otherwise, i.e. if there is a discrepency between orthogroup clustering and Virulence factor prediction.
Green homologs (same orthogroup) are not positive hit(s) for the considered Virulence factor.
Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or Virulence factor prediction.

Description

Protein ECA polysaccharide chain length modulation protein
VF ID VF0392
Category Immune modulation
Protein ID WP_005181087
Characteristics Clinical Y. enterocolitica isolates from humans predominantly belong to serotypes O:3, O:9, O:8 and O:5,27; Y. enterocolitica O antigen expression is temperature regulated.
Function LPS O antigen mutants were severely impaired in their ability to colonize the Peyer's patches and did not colonize spleen and liver. The absence of O antigen in the outer membrane affects the expression of other Yersinia virulence factors.
Vf_category_id VFC0258

Occurence in the database

VFG023778 is associated with 7 different proteins
The 7 proteins are classified into 1 different orthogroup(s)
Orthogroup Locus Start Stop S. Gene Product Organism
0 group_1386 FBDBKF_08225 22844 23899 1 wzzE ECA polysaccharide chain length modulation protein Morganella morganii S1
1 group_1386 EHELCC_13300 139826 140881 -1 wzzE ECA polysaccharide chain length modulation protein Morganella morganii S2
2 group_1386 NLDBIP_13640 139826 140881 -1 wzzE ECA polysaccharide chain length modulation protein Morganella morganii S4
3 group_1386 LHKJJB_12915 21562 22617 1 wzzE ECA polysaccharide chain length modulation protein Morganella morganii S3
4 group_1386 HKOGLL_12115 139826 140881 -1 wzzE ECA polysaccharide chain length modulation protein Morganella morganii S5
5 group_1386 F4V73_RS18775 24007 25062 1 wzzE ECA polysaccharide chain length modulation protein Morganella psychrotolerans
6 group_1386 PMI_RS16485 3636211 3637269 1 wzzE ECA polysaccharide chain length modulation protein Proteus mirabilis HI4320