VFG019018


Help to interpret the results

Three outputs have been generated:
General: this result contains the description and frequency of the selected Virulence factors VFG019018, of which KO pathways and KO modules it is part. Additionally, its occurence in the database is reported.
Proteins list: list of occurences of the Virulence factors within the database. 5 occurences are identified. The table reports the orthogroup, the organism in which each occurrence has been found, and the locus tag enriched by start and stop position, strand, gene name and product.
Clicking on the Ortohgroup name or locus you will be redirected to further info.
Profiles: Phylogenetic tree annotated with
- the presence of the Virulence factor(s) of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported Virulence factors has been clustered.
In red the Virulence factors with positive hit(s) in the corresponding genome.
In green the discrepencies between orthogroup clustering and Virulence factors prediction. Green homologs (same orthogroup) are not positive hit(s) for the considered Virulence factors.

Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or Virulence factors prediction.

Description

Protein NAD-dependent epimerase/dehydratase family protein
VF ID VF0392
Category Immune modulation
Protein ID WP_192575220
Characteristics Clinical Y. enterocolitica isolates from humans predominantly belong to serotypes O:3, O:9, O:8 and O:5,27; Y. enterocolitica O antigen expression is temperature regulated.
Function LPS O antigen mutants were severely impaired in their ability to colonize the Peyer's patches and did not colonize spleen and liver. The absence of O antigen in the outer membrane affects the expression of other Yersinia virulence factors.
Vf_category_id VFC0258

Occurence in the database

VFG019018 is associated with 5 different proteins (see tab "Protein list" and "Profile")
The 5 proteins are classified into 1 different orthogroup(s)
# Orthogroup Locus Start Stop S. Gene Product Organism
0 group_2175 FBDBKF_16360 59123 60073 -1 UDP-glucose 4-epimerase Morganella morganii S1
1 group_2175 EHELCC_16395 59123 60073 -1 UDP-glucose 4-epimerase Morganella morganii S2
2 group_2175 NLDBIP_16945 2097 3047 1 UDP-glucose 4-epimerase Morganella morganii S4
3 group_2175 LHKJJB_16865 5199 6149 1 UDP-glucose 4-epimerase Morganella morganii S3
4 group_2175 HKOGLL_16975 59123 60073 -1 UDP-glucose 4-epimerase Morganella morganii S5