COG2169


Help to interpret the results

Three outputs have been generated:
General: this result contains the description and frequency of the selected COG entries COG2169, of which KO pathways and KO modules it is part. Additionally, its occurence in the database is reported.
Proteins list: list of occurences of the COG entries within the database. 8 occurences are identified. The table reports the orthogroup, the organism in which each occurrence has been found, and the locus tag enriched by start and stop position, strand, gene name and product.
Clicking on the Ortohgroup name or locus you will be redirected to further info.
Profiles: Phylogenetic tree annotated with
- the presence of the COG entry(ies) of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported COG entries has been clustered.
In red the COG entries with positive hit(s) in the corresponding genome.
In green the discrepencies between orthogroup clustering and COG entries prediction. Green homologs (same orthogroup) are not positive hit(s) for the considered COG entries.

Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or COG entries prediction.

Description

Description Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains
Function(s) descr. Replication, recombination and repair (L)

Occurence in the database

COG2169 is associated with 8 different proteins (see tab "Protein list" and "Profile")
The 8 proteins are classified into 2 different orthogroup(s)
# Orthogroup Locus Start Stop S. Gene Product Organism
0 group_691 FBDBKF_02915 276799 277881 -1 ada bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada Morganella morganii S1
1 group_691 EHELCC_03385 664619 665701 -1 ada bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada Morganella morganii S2
2 group_691 NLDBIP_00075 14435 15517 1 ada bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada Morganella morganii S4
3 group_691 LHKJJB_01960 377168 378250 -1 ada bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada Morganella morganii S3
4 group_691 HKOGLL_02000 382679 383761 -1 ada bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada Morganella morganii S5
5 group_691 F4V73_RS05360 1136905 1137993 -1 ada bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada Morganella psychrotolerans
6 group_691 PMI_RS05985 1312855 1313718 1 methylated-DNA--[protein]-cysteine S-methyltransferase Proteus mirabilis HI4320
7 group_1462 PMI_RS13290 2949698 2950453 -1 helix-turn-helix domain-containing protein Proteus mirabilis HI4320