M00026


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Kegg module M00026 is descriptive of Histidine biosynthesis, PRPP => histidine module, which is part of the Amino acid metabolism category and Histidine metabolism subcategory.

In General the list of Ko entries of M00026 Kegg module is reported. Each Ko entry is clickable and redirects the user to the specifc Kegg Ortholog page with further info about its identification within the genomes in association with the Orthogroups classification.
In Profile + homologs the distribution of the Kegg entries of Histidine biosynthesis, PRPP => histidine module is displayed. Given a Kegg entry and a genome, a red box indicates that one or more loci have been annotated with, while a green box indicates that no locus/loci has(have) been annotated with it, but it/they is/are part of an Orthologous group in which other members have been annotated with that Kegg entry, so it is likely that this copy(ies) also performs this Kegg function.
If all the Kegg entries required by the model to be funcitonal are present, the letter 'C'' is reported, otherwise 'I' singals an incomplet module.
Note that a Kegg module may accept alternative Ko or set of Kegg orthologs to be functional. This means that some missing Ko do not impact the module completeness.

Check the composition of M00026 Kegg module

Id Description
K00013 histidinol dehydrogenase [EC:1.1.1.23]
K00765 ATP phosphoribosyltransferase [EC:2.4.2.17]
K00817 histidinol-phosphate aminotransferase [EC:2.6.1.9]
K01089 imidazoleglycerol-phosphate dehydratase / histidinol-phosphatase [EC:4.2.1.19 3.1.3.15]
K01496 phosphoribosyl-AMP cyclohydrolase [EC:3.5.4.19]
K01523 phosphoribosyl-ATP pyrophosphohydrolase [EC:3.6.1.31]
K01663 imidazole glycerol-phosphate synthase [EC:4.3.2.10]
K01693 imidazoleglycerol-phosphate dehydratase [EC:4.2.1.19]
K01814 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [EC:5.3.1.16]
K02500 imidazole glycerol-phosphate synthase subunit HisF [EC:4.3.2.10]
K02501 imidazole glycerol-phosphate synthase subunit HisH [EC:4.3.2.10]
K02502 ATP phosphoribosyltransferase regulatory subunit
K04486 histidinol-phosphatase (PHP family) [EC:3.1.3.15]
K05602 histidinol-phosphatase [EC:3.1.3.15]
K11755 phosphoribosyl-AMP cyclohydrolase / phosphoribosyl-ATP pyrophosphohydrolase [EC:3.5.4.19 3.6.1.31]
K14152 phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP cyclohydrolase / histidinol dehydrogenase [EC:3.6.1.31 3.5.4.19 1.1.1.23]
K18649 inositol-phosphate phosphatase / L-galactose 1-phosphate phosphatase / histidinol-phosphatase [EC:3.1.3.25 3.1.3.93 3.1.3.15]
K24017 phosphoribosyl isomerase A [EC:5.3.1.16 5.3.1.24]