Lipid and atherosclerosis


Help to interpret the results


The page contains two contents:
General: this table lists the KO entries and their description specific to this pathway, and provides their frequencies in Morganella psychrotolerans and in the whole dataset.
Profile + homologs: the distribution of the Kegg entries of Lipid and atherosclerosis Kegg pathway is displayed here. Given a Kegg entry and a genome, a red box indicates that one or more loci have been annotated with, while a green box indicates that no locus/loci has(have) been annotated with it, but it/they is/are part of an Orthologous group in which other members have been annotated with that Kegg entry, so it is likely that this copy(ies) also performs this Kegg function.

Check the composition of the Lipid and atherosclerosis pathway


KO Description #in this genome All occurrences
K00922 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153] 0 0
K01116 phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11] 0 0
K01370 caspase 1 [EC:3.4.22.36] 0 0
K01388 matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7] 0 0
K01394 matrix metalloproteinase-3 (stromelysin 1, progelatinase) [EC:3.4.24.17] 0 0
K01403 matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35] 0 0
K02084 apoptotic protease-activating factor 0 0
K02158 Bcl-2-antagonist of cell death 0 0
K02159 apoptosis regulator BAX 0 0
K02161 apoptosis regulator Bcl-2 0 0
K02183 calmodulin 0 0
K02187 caspase 3 [EC:3.4.22.56] 0 0
K02580 nuclear factor NF-kappa-B p105 subunit 0 0
K02649 phosphoinositide-3-kinase regulatory subunit alpha/beta/delta 0 0
K02677 classical protein kinase C alpha type [EC:2.7.11.13] 0 0
K02833 GTPase HRas 0 0
K03083 glycogen synthase kinase 3 beta [EC:2.7.11.26] 0 0
K03156 tumor necrosis factor superfamily, member 2 0 0
K03158 tumor necrosis factor receptor superfamily member 1A 0 0
K03160 tumor necrosis factor receptor superfamily member 5 0 0
K03161 tumor necrosis factor ligand superfamily member 5 0 0
K03173 TNF receptor-associated factor 2 [EC:2.3.2.27] 0 0
K03174 TNF receptor-associated factor 3 0 0
K03175 TNF receptor-associated factor 6 [EC:2.3.2.27] 0 0
K03237 translation initiation factor 2 subunit 1 0 0
K03283 heat shock 70kDa protein 1/6/8 0 0
K04077 chaperonin GroEL [EC:5.6.1.7] 1 7
K04079 molecular chaperone HtpG 1 7
K04348 serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16] 0 0
K04353 Ras-related protein Rap-1A 0 0
K04371 mitogen-activated protein kinase 1/3 [EC:2.7.11.24] 0 0
K04374 cyclic AMP-dependent transcription factor ATF-4 0 0
K04379 proto-oncogene protein c-fos 0 0
K04389 tumor necrosis factor ligand superfamily member 6 0 0
K04390 tumor necrosis factor receptor superfamily member 6 0 0
K04391 monocyte differentiation antigen CD14 0 0
K04392 Ras-related C3 botulinum toxin substrate 1 0 0
K04393 cell division control protein 42 0 0
K04396 caspase 6 [EC:3.4.22.59] 0 0
K04397 caspase 7 [EC:3.4.22.60] 0 0
K04398 caspase 8 [EC:3.4.22.61] 0 0
K04399 caspase 9 [EC:3.4.22.62] 0 0
K04403 TAK1-binding protein 1 0 0
K04404 TAK1-binding protein 2 0 0
K04426 mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25] 0 0
K04427 mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25] 0 0
K04430 mitogen-activated protein kinase kinase 4 [EC:2.7.12.2] 0 0
K04431 mitogen-activated protein kinase kinase 7 [EC:2.7.12.2] 0 0
K04432 mitogen-activated protein kinase kinase 3 [EC:2.7.12.2] 0 0
K04433 mitogen-activated protein kinase kinase 6 [EC:2.7.12.2] 0 0
K04440 mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24] 0 0
K04441 p38 MAP kinase [EC:2.7.11.24] 0 0
K04446 nuclear factor of activated T-cells, cytoplasmic 1 0 0
K04447 Janus kinase 2 [EC:2.7.10.2] 0 0
K04448 transcription factor AP-1 0 0
K04451 tumor protein p53 0 0
K04452 DNA damage-inducible transcript 3 0 0
K04456 RAC serine/threonine-protein kinase [EC:2.7.11.1] 0 0
K04467 inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10] 0 0
K04513 Ras homolog gene family, member A 0 0
K04515 calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17] 0 0
K04519 interleukin 1 beta 0 0
K04564 superoxide dismutase, Fe-Mn family [EC:1.15.1.1] 2 14
K04570 Bcl-2-like 1 (apoptosis regulator Bcl-X) 0 0
K04692 signal transducer and activator of transcription 3 0 0
K04721 tumor necrosis factor ligand superfamily member 10 0 0
K04722 tumor necrosis factor receptor superfamily member 10A/B 0 0
K04726 BH3 interacting domain death agonist 0 0
K04729 myeloid differentiation primary response protein MyD88 0 0
K04730 interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1] 0 0
K04733 interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1] 0 0
K04734 NF-kappa-B inhibitor alpha 0 0
K04735 transcription factor p65 0 0
K04958 inositol 1,4,5-triphosphate receptor type 1 0 0
K05399 lipopolysaccharide-binding protein 0 0
K05400 lymphocyte antigen 96 0 0
K05403 toll-interleukin 1 receptor (TIR) domain-containing adaptor protein 0 0
K05405 interleukin 6 0 0
K05406 interleukin 12A 0 0
K05408 C-C motif chemokine 3 0 0
K05409 TRIF-related adaptor molecule 0 0
K05410 TANK-binding kinase 1 [EC:2.7.11.10] 0 0
K05411 interferon regulatory factor 3 0 0
K05414 interferon alpha 0 0
K05415 interferon beta 0 0
K05425 interleukin 12B 0 0
K05482 interleukin 18 0 0
K05505 C-X-C motif chemokine 1/2/3 0 0
K05638 nuclear factor erythroid 2-related factor 2 0 0
K05641 ATP-binding cassette, subfamily A (ABC1), member 1 0 0
K05679 ATP-binding cassette, subfamily G (WHITE), member 1 0 0
K05704 tyrosine-protein kinase Src [EC:2.7.10.2] 0 0
K05725 focal adhesion kinase 1 [EC:2.7.10.2] 0 0
K05730 guanine nucleotide exchange factor VAV 0 0
K05842 toll-like receptor adapter molecule 1 0 0
K05854 tyrosine-protein kinase Lyn [EC:2.7.10.2] 0 0
K05858 phosphatidylinositol phospholipase C, beta [EC:3.1.4.11] 0 0
K06259 CD36 antigen 0 0
K06268 serine/threonine-protein phosphatase 2B regulatory subunit 0 0
K06276 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1] 0 0
K06490 intercellular adhesion molecule 1 0 0
K06494 selectin, endothelial cell 0 0
K06496 selectin, platelet 0 0
K06527 vascular cell adhesion molecule 1 0 0
K07209 inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10] 0 0
K07210 inhibitor of nuclear factor kappa-B kinase subunit gamma 0 0
K07211 inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10] 0 0
K07408 cytochrome P450 family 1 subfamily A1 [EC:1.14.14.1] 0 0
K07418 cytochrome P450 family 2 subfamily J [EC:1.14.14.1 1.14.14.73 1.14.14.74 1.14.14.75] 0 0
K07827 GTPase KRas 0 0
K07828 GTPase NRas 0 0
K07836 Ras-related protein Rap-1B 0 0
K08008 NADPH oxidase 1 0 0
K08009 cytochrome b-245, alpha polypeptide 0 0
K08010 neutrophil cytosolic factor 2 0 0
K08011 neutrophil cytosolic factor 1 0 0
K08012 neutrophil cytosolic factor 4 0 0
K08524 retinoid X receptor alpha 0 0
K08525 retinoid X receptor beta 0 0
K08526 retinoid X receptor gamma 0 0
K08530 peroxisome proliferator-activated receptor gamma 0 0
K08738 cytochrome c 0 0
K08757 apolipoprotein A-I 0 0
K08760 apolipoprotein A-IV 0 0
K08763 oxidised low-density lipoprotein receptor 1 0 0
K08852 serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-] 0 0
K08860 eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1] 0 0
K09027 X box-binding protein 1 0 0
K09054 cyclic AMP-dependent transcription factor ATF-6 alpha 0 0
K09364 POU domain transcription factor, class 2 0 0
K09447 interferon regulatory factor 7 0 0
K09487 heat shock protein 90kDa beta 0 0
K09489 heat shock 70kDa protein 4 0 0
K09490 endoplasmic reticulum chaperone BiP [EC:3.6.4.10] 0 0
K10030 interleukin 8 0 0
K10159 toll-like receptor 2 0 0
K10160 toll-like receptor 4 0 0
K10169 toll-like receptor 6 0 0
K10645 E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27] 0 0
K10950 ERO1-like protein alpha [EC:1.8.4.-] 0 0
K12330 Rho guanine nucleotide exchange factor 1 0 0
K12473 low-density lipoprotein receptor 0 0
K12499 C-C motif chemokine 5 0 0
K12650 TRAF family member-associated NF-kappa-B activator 0 0
K12799 apoptosis-associated speck-like protein containing a CARD 0 0
K12800 NACHT, LRR and PYD domains-containing protein 3 0 0
K13242 nitric-oxide synthase, endothelial [EC:1.14.13.39] 0 0
K14462 apolipoprotein B 0 0
K14624 C-C motif chemokine 2 0 0
K17332 nuclear factor of activated T-cells, cytoplasmic 2 0 0
K17333 nuclear factor of activated T-cells, cytoplasmic 3 0 0
K17388 Rho-associated protein kinase 2 [EC:2.7.11.1] 0 0
K17683 cytochrome P450 family 2 subfamily A6 [EC:1.14.14.-] 0 0
K17709 cytochrome P450 family 2 subfamily B6 [EC:1.14.14.-] 0 0
K17718 cytochrome P450 family 2 subfamily C8 [EC:1.14.14.1] 0 0
K17719 cytochrome P450 family 2 subfamily C9 [EC:1.14.14.51 1.14.14.52 1.14.14.53 1.14.14.-] 0 0
K19722 receptor for advanced glycosylation end products 0 0
K20053 very low-density lipoprotein receptor 0 0
K21421 NADPH oxidase 2 [EC:1.-.-.-] 0 0
K26598 heat shock 70kDa protein 2 0 0