Help to interpret the results
The page contains two contents:
General: this table lists the KO entries and their description specific to this pathway, and provides their frequencies in Morganella morganii S3 and in the whole dataset.
Profile + homologs: the distribution of the Kegg entries of Lipid and atherosclerosis Kegg pathway is displayed here. Given a Kegg entry and a genome, a red box indicates that one or more loci have been annotated with, while a green box indicates that no locus/loci has(have) been annotated with it, but it/they is/are part of an Orthologous group in which other members have been annotated with that Kegg entry, so it is likely that this copy(ies) also performs this Kegg function.
Check the composition of the Lipid and atherosclerosis pathway
| KO | Description | #in this genome | All occurrences |
|---|---|---|---|
| K00922 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153] | 0 | 0 |
| K01116 | phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11] | 0 | 0 |
| K01370 | caspase 1 [EC:3.4.22.36] | 0 | 0 |
| K01388 | matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7] | 0 | 0 |
| K01394 | matrix metalloproteinase-3 (stromelysin 1, progelatinase) [EC:3.4.24.17] | 0 | 0 |
| K01403 | matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35] | 0 | 0 |
| K02084 | apoptotic protease-activating factor | 0 | 0 |
| K02158 | Bcl-2-antagonist of cell death | 0 | 0 |
| K02159 | apoptosis regulator BAX | 0 | 0 |
| K02161 | apoptosis regulator Bcl-2 | 0 | 0 |
| K02183 | calmodulin | 0 | 0 |
| K02187 | caspase 3 [EC:3.4.22.56] | 0 | 0 |
| K02580 | nuclear factor NF-kappa-B p105 subunit | 0 | 0 |
| K02649 | phosphoinositide-3-kinase regulatory subunit alpha/beta/delta | 0 | 0 |
| K02677 | classical protein kinase C alpha type [EC:2.7.11.13] | 0 | 0 |
| K02833 | GTPase HRas | 0 | 0 |
| K03083 | glycogen synthase kinase 3 beta [EC:2.7.11.26] | 0 | 0 |
| K03156 | tumor necrosis factor superfamily, member 2 | 0 | 0 |
| K03158 | tumor necrosis factor receptor superfamily member 1A | 0 | 0 |
| K03160 | tumor necrosis factor receptor superfamily member 5 | 0 | 0 |
| K03161 | tumor necrosis factor ligand superfamily member 5 | 0 | 0 |
| K03173 | TNF receptor-associated factor 2 [EC:2.3.2.27] | 0 | 0 |
| K03174 | TNF receptor-associated factor 3 | 0 | 0 |
| K03175 | TNF receptor-associated factor 6 [EC:2.3.2.27] | 0 | 0 |
| K03237 | translation initiation factor 2 subunit 1 | 0 | 0 |
| K03283 | heat shock 70kDa protein 1/6/8 | 0 | 0 |
| K04077 | chaperonin GroEL [EC:5.6.1.7] | 1 | 7 |
| K04079 | molecular chaperone HtpG | 1 | 7 |
| K04348 | serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16] | 0 | 0 |
| K04353 | Ras-related protein Rap-1A | 0 | 0 |
| K04371 | mitogen-activated protein kinase 1/3 [EC:2.7.11.24] | 0 | 0 |
| K04374 | cyclic AMP-dependent transcription factor ATF-4 | 0 | 0 |
| K04379 | proto-oncogene protein c-fos | 0 | 0 |
| K04389 | tumor necrosis factor ligand superfamily member 6 | 0 | 0 |
| K04390 | tumor necrosis factor receptor superfamily member 6 | 0 | 0 |
| K04391 | monocyte differentiation antigen CD14 | 0 | 0 |
| K04392 | Ras-related C3 botulinum toxin substrate 1 | 0 | 0 |
| K04393 | cell division control protein 42 | 0 | 0 |
| K04396 | caspase 6 [EC:3.4.22.59] | 0 | 0 |
| K04397 | caspase 7 [EC:3.4.22.60] | 0 | 0 |
| K04398 | caspase 8 [EC:3.4.22.61] | 0 | 0 |
| K04399 | caspase 9 [EC:3.4.22.62] | 0 | 0 |
| K04403 | TAK1-binding protein 1 | 0 | 0 |
| K04404 | TAK1-binding protein 2 | 0 | 0 |
| K04426 | mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25] | 0 | 0 |
| K04427 | mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25] | 0 | 0 |
| K04430 | mitogen-activated protein kinase kinase 4 [EC:2.7.12.2] | 0 | 0 |
| K04431 | mitogen-activated protein kinase kinase 7 [EC:2.7.12.2] | 0 | 0 |
| K04432 | mitogen-activated protein kinase kinase 3 [EC:2.7.12.2] | 0 | 0 |
| K04433 | mitogen-activated protein kinase kinase 6 [EC:2.7.12.2] | 0 | 0 |
| K04440 | mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24] | 0 | 0 |
| K04441 | p38 MAP kinase [EC:2.7.11.24] | 0 | 0 |
| K04446 | nuclear factor of activated T-cells, cytoplasmic 1 | 0 | 0 |
| K04447 | Janus kinase 2 [EC:2.7.10.2] | 0 | 0 |
| K04448 | transcription factor AP-1 | 0 | 0 |
| K04451 | tumor protein p53 | 0 | 0 |
| K04452 | DNA damage-inducible transcript 3 | 0 | 0 |
| K04456 | RAC serine/threonine-protein kinase [EC:2.7.11.1] | 0 | 0 |
| K04467 | inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10] | 0 | 0 |
| K04513 | Ras homolog gene family, member A | 0 | 0 |
| K04515 | calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17] | 0 | 0 |
| K04519 | interleukin 1 beta | 0 | 0 |
| K04564 | superoxide dismutase, Fe-Mn family [EC:1.15.1.1] | 2 | 14 |
| K04570 | Bcl-2-like 1 (apoptosis regulator Bcl-X) | 0 | 0 |
| K04692 | signal transducer and activator of transcription 3 | 0 | 0 |
| K04721 | tumor necrosis factor ligand superfamily member 10 | 0 | 0 |
| K04722 | tumor necrosis factor receptor superfamily member 10A/B | 0 | 0 |
| K04726 | BH3 interacting domain death agonist | 0 | 0 |
| K04729 | myeloid differentiation primary response protein MyD88 | 0 | 0 |
| K04730 | interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1] | 0 | 0 |
| K04733 | interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1] | 0 | 0 |
| K04734 | NF-kappa-B inhibitor alpha | 0 | 0 |
| K04735 | transcription factor p65 | 0 | 0 |
| K04958 | inositol 1,4,5-triphosphate receptor type 1 | 0 | 0 |
| K05399 | lipopolysaccharide-binding protein | 0 | 0 |
| K05400 | lymphocyte antigen 96 | 0 | 0 |
| K05403 | toll-interleukin 1 receptor (TIR) domain-containing adaptor protein | 0 | 0 |
| K05405 | interleukin 6 | 0 | 0 |
| K05406 | interleukin 12A | 0 | 0 |
| K05408 | C-C motif chemokine 3 | 0 | 0 |
| K05409 | TRIF-related adaptor molecule | 0 | 0 |
| K05410 | TANK-binding kinase 1 [EC:2.7.11.10] | 0 | 0 |
| K05411 | interferon regulatory factor 3 | 0 | 0 |
| K05414 | interferon alpha | 0 | 0 |
| K05415 | interferon beta | 0 | 0 |
| K05425 | interleukin 12B | 0 | 0 |
| K05482 | interleukin 18 | 0 | 0 |
| K05505 | C-X-C motif chemokine 1/2/3 | 0 | 0 |
| K05638 | nuclear factor erythroid 2-related factor 2 | 0 | 0 |
| K05641 | ATP-binding cassette, subfamily A (ABC1), member 1 | 0 | 0 |
| K05679 | ATP-binding cassette, subfamily G (WHITE), member 1 | 0 | 0 |
| K05704 | tyrosine-protein kinase Src [EC:2.7.10.2] | 0 | 0 |
| K05725 | focal adhesion kinase 1 [EC:2.7.10.2] | 0 | 0 |
| K05730 | guanine nucleotide exchange factor VAV | 0 | 0 |
| K05842 | toll-like receptor adapter molecule 1 | 0 | 0 |
| K05854 | tyrosine-protein kinase Lyn [EC:2.7.10.2] | 0 | 0 |
| K05858 | phosphatidylinositol phospholipase C, beta [EC:3.1.4.11] | 0 | 0 |
| K06259 | CD36 antigen | 0 | 0 |
| K06268 | serine/threonine-protein phosphatase 2B regulatory subunit | 0 | 0 |
| K06276 | 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1] | 0 | 0 |
| K06490 | intercellular adhesion molecule 1 | 0 | 0 |
| K06494 | selectin, endothelial cell | 0 | 0 |
| K06496 | selectin, platelet | 0 | 0 |
| K06527 | vascular cell adhesion molecule 1 | 0 | 0 |
| K07209 | inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10] | 0 | 0 |
| K07210 | inhibitor of nuclear factor kappa-B kinase subunit gamma | 0 | 0 |
| K07211 | inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10] | 0 | 0 |
| K07408 | cytochrome P450 family 1 subfamily A1 [EC:1.14.14.1] | 0 | 0 |
| K07418 | cytochrome P450 family 2 subfamily J [EC:1.14.14.1 1.14.14.73 1.14.14.74 1.14.14.75] | 0 | 0 |
| K07827 | GTPase KRas | 0 | 0 |
| K07828 | GTPase NRas | 0 | 0 |
| K07836 | Ras-related protein Rap-1B | 0 | 0 |
| K08008 | NADPH oxidase 1 | 0 | 0 |
| K08009 | cytochrome b-245, alpha polypeptide | 0 | 0 |
| K08010 | neutrophil cytosolic factor 2 | 0 | 0 |
| K08011 | neutrophil cytosolic factor 1 | 0 | 0 |
| K08012 | neutrophil cytosolic factor 4 | 0 | 0 |
| K08524 | retinoid X receptor alpha | 0 | 0 |
| K08525 | retinoid X receptor beta | 0 | 0 |
| K08526 | retinoid X receptor gamma | 0 | 0 |
| K08530 | peroxisome proliferator-activated receptor gamma | 0 | 0 |
| K08738 | cytochrome c | 0 | 0 |
| K08757 | apolipoprotein A-I | 0 | 0 |
| K08760 | apolipoprotein A-IV | 0 | 0 |
| K08763 | oxidised low-density lipoprotein receptor 1 | 0 | 0 |
| K08852 | serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-] | 0 | 0 |
| K08860 | eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1] | 0 | 0 |
| K09027 | X box-binding protein 1 | 0 | 0 |
| K09054 | cyclic AMP-dependent transcription factor ATF-6 alpha | 0 | 0 |
| K09364 | POU domain transcription factor, class 2 | 0 | 0 |
| K09447 | interferon regulatory factor 7 | 0 | 0 |
| K09487 | heat shock protein 90kDa beta | 0 | 0 |
| K09489 | heat shock 70kDa protein 4 | 0 | 0 |
| K09490 | endoplasmic reticulum chaperone BiP [EC:3.6.4.10] | 0 | 0 |
| K10030 | interleukin 8 | 0 | 0 |
| K10159 | toll-like receptor 2 | 0 | 0 |
| K10160 | toll-like receptor 4 | 0 | 0 |
| K10169 | toll-like receptor 6 | 0 | 0 |
| K10645 | E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27] | 0 | 0 |
| K10950 | ERO1-like protein alpha [EC:1.8.4.-] | 0 | 0 |
| K12330 | Rho guanine nucleotide exchange factor 1 | 0 | 0 |
| K12473 | low-density lipoprotein receptor | 0 | 0 |
| K12499 | C-C motif chemokine 5 | 0 | 0 |
| K12650 | TRAF family member-associated NF-kappa-B activator | 0 | 0 |
| K12799 | apoptosis-associated speck-like protein containing a CARD | 0 | 0 |
| K12800 | NACHT, LRR and PYD domains-containing protein 3 | 0 | 0 |
| K13242 | nitric-oxide synthase, endothelial [EC:1.14.13.39] | 0 | 0 |
| K14462 | apolipoprotein B | 0 | 0 |
| K14624 | C-C motif chemokine 2 | 0 | 0 |
| K17332 | nuclear factor of activated T-cells, cytoplasmic 2 | 0 | 0 |
| K17333 | nuclear factor of activated T-cells, cytoplasmic 3 | 0 | 0 |
| K17388 | Rho-associated protein kinase 2 [EC:2.7.11.1] | 0 | 0 |
| K17683 | cytochrome P450 family 2 subfamily A6 [EC:1.14.14.-] | 0 | 0 |
| K17709 | cytochrome P450 family 2 subfamily B6 [EC:1.14.14.-] | 0 | 0 |
| K17718 | cytochrome P450 family 2 subfamily C8 [EC:1.14.14.1] | 0 | 0 |
| K17719 | cytochrome P450 family 2 subfamily C9 [EC:1.14.14.51 1.14.14.52 1.14.14.53 1.14.14.-] | 0 | 0 |
| K19722 | receptor for advanced glycosylation end products | 0 | 0 |
| K20053 | very low-density lipoprotein receptor | 0 | 0 |
| K21421 | NADPH oxidase 2 [EC:1.-.-.-] | 0 | 0 |
| K26598 | heat shock 70kDa protein 2 | 0 | 0 |