Help to interpret the results
The page contains two contents:
General: this table lists the KO entries and their description specific to this pathway, and provides their frequencies in Morganella morganii S5 and in the whole dataset.
Profile + homologs: the distribution of the Kegg entries of Proteoglycans in cancer Kegg pathway is displayed here. Given a Kegg entry and a genome, a red box indicates that one or more loci have been annotated with, while a green box indicates that no locus/loci has(have) been annotated with it, but it/they is/are part of an Orthologous group in which other members have been annotated with that Kegg entry, so it is likely that this copy(ies) also performs this Kegg function.
Check the composition of the Proteoglycans in cancer pathway
| KO | Description | #in this genome | All occurrences |
|---|---|---|---|
| K00182 | wingless-type MMTV integration site family, member 2 | 0 | 0 |
| K00312 | wingless-type MMTV integration site family, member 3 | 0 | 0 |
| K00408 | wingless-type MMTV integration site family, member 4 | 0 | 0 |
| K00444 | wingless-type MMTV integration site family, member 5 | 0 | 0 |
| K00445 | wingless-type MMTV integration site family, member 6 | 0 | 0 |
| K00572 | wingless-type MMTV integration site family, member 7 | 0 | 0 |
| K00714 | wingless-type MMTV integration site family, member 8 | 0 | 0 |
| K00922 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153] | 0 | 0 |
| K01064 | wingless-type MMTV integration site family, member 9 | 0 | 0 |
| K01116 | phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11] | 0 | 0 |
| K01348 | urokinase plasminogen activator [EC:3.4.21.73] | 0 | 0 |
| K01357 | wingless-type MMTV integration site family, member 10 | 0 | 0 |
| K01365 | cathepsin L [EC:3.4.22.15] | 0 | 0 |
| K01384 | wingless-type MMTV integration site family, member 11 | 0 | 0 |
| K01398 | matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24] | 0 | 0 |
| K01403 | matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35] | 0 | 0 |
| K01558 | wingless-type MMTV integration site family, member 16 | 0 | 0 |
| K02105 | catenin beta 1 | 0 | 0 |
| K02187 | caspase 3 [EC:3.4.22.56] | 0 | 0 |
| K02235 | frizzled 2 | 0 | 0 |
| K02329 | frizzled 3 | 0 | 0 |
| K02354 | frizzled 4 | 0 | 0 |
| K02375 | frizzled 5/8 | 0 | 0 |
| K02376 | frizzled 6 | 0 | 0 |
| K02432 | frizzled 1/7 | 0 | 0 |
| K02649 | phosphoinositide-3-kinase regulatory subunit alpha/beta/delta | 0 | 0 |
| K02677 | classical protein kinase C alpha type [EC:2.7.11.13] | 0 | 0 |
| K02833 | GTPase HRas | 0 | 0 |
| K02842 | frizzled 9/10 | 0 | 0 |
| K02991 | small subunit ribosomal protein S6e | 0 | 0 |
| K03099 | son of sevenless | 0 | 0 |
| K03156 | tumor necrosis factor superfamily, member 2 | 0 | 0 |
| K03209 | wingless-type MMTV integration site family, member 1 | 0 | 0 |
| K03258 | translation initiation factor 4B | 0 | 0 |
| K03685 | ribonuclease III [EC:3.1.26.3] | 1 | 7 |
| K03985 | plasminogen activator, urokinase receptor | 0 | 0 |
| K04345 | protein kinase A [EC:2.7.11.11] | 0 | 0 |
| K04361 | epidermal growth factor receptor [EC:2.7.10.1] | 0 | 0 |
| K04362 | fibroblast growth factor receptor 1 [EC:2.7.10.1] | 0 | 0 |
| K04364 | growth factor receptor-bound protein 2 | 0 | 0 |
| K04365 | B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1] | 0 | 0 |
| K04366 | RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1] | 0 | 0 |
| K04368 | mitogen-activated protein kinase kinase 1 [EC:2.7.12.2] | 0 | 0 |
| K04369 | mitogen-activated protein kinase kinase 2 [EC:2.7.12.2] | 0 | 0 |
| K04371 | mitogen-activated protein kinase 1/3 [EC:2.7.11.24] | 0 | 0 |
| K04375 | ETS domain-containing protein Elk-1 | 0 | 0 |
| K04377 | Myc proto-oncogene protein | 0 | 0 |
| K04389 | tumor necrosis factor ligand superfamily member 6 | 0 | 0 |
| K04390 | tumor necrosis factor receptor superfamily member 6 | 0 | 0 |
| K04392 | Ras-related C3 botulinum toxin substrate 1 | 0 | 0 |
| K04393 | cell division control protein 42 | 0 | 0 |
| K04409 | p21-activated kinase 1 [EC:2.7.11.1] | 0 | 0 |
| K04437 | filamin | 0 | 0 |
| K04441 | p38 MAP kinase [EC:2.7.11.24] | 0 | 0 |
| K04451 | tumor protein p53 | 0 | 0 |
| K04456 | RAC serine/threonine-protein kinase [EC:2.7.11.1] | 0 | 0 |
| K04500 | mothers against decapentaplegic homolog 2 | 0 | 0 |
| K04503 | G1/S-specific cyclin-D1 | 0 | 0 |
| K04513 | Ras homolog gene family, member A | 0 | 0 |
| K04514 | Rho-associated protein kinase 1 [EC:2.7.11.1] | 0 | 0 |
| K04515 | calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17] | 0 | 0 |
| K04660 | decorin | 0 | 0 |
| K04688 | ribosomal protein S6 kinase beta [EC:2.7.11.1] | 0 | 0 |
| K04692 | signal transducer and activator of transcription 3 | 0 | 0 |
| K04707 | E3 ubiquitin-protein ligase CBL [EC:2.3.2.27] | 0 | 0 |
| K04958 | inositol 1,4,5-triphosphate receptor type 1 | 0 | 0 |
| K04959 | inositol 1,4,5-triphosphate receptor type 2 | 0 | 0 |
| K04960 | inositol 1,4,5-triphosphate receptor type 3 | 0 | 0 |
| K05083 | receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1] | 0 | 0 |
| K05084 | receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1] | 0 | 0 |
| K05085 | receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1] | 0 | 0 |
| K05087 | insulin-like growth factor 1 receptor [EC:2.7.10.1] | 0 | 0 |
| K05098 | kinase insert domain protein receptor [EC:2.7.10.1] | 0 | 0 |
| K05099 | proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1] | 0 | 0 |
| K05425 | interleukin 12B | 0 | 0 |
| K05448 | vascular endothelial growth factor A | 0 | 0 |
| K05459 | insulin-like growth factor 1 | 0 | 0 |
| K05460 | hepatocyte growth factor | 0 | 0 |
| K05692 | actin beta/gamma 1 | 0 | 0 |
| K05697 | tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48] | 0 | 0 |
| K05704 | tyrosine-protein kinase Src [EC:2.7.10.2] | 0 | 0 |
| K05717 | fibronectin 1 | 0 | 0 |
| K05719 | integrin beta 1 | 0 | 0 |
| K05725 | focal adhesion kinase 1 [EC:2.7.10.2] | 0 | 0 |
| K05730 | guanine nucleotide exchange factor VAV | 0 | 0 |
| K05731 | T-lymphoma invasion and metastasis-inducing protein 1 | 0 | 0 |
| K05742 | solute carrier family 9 (sodium/hydrogen exchanger), member 1 | 0 | 0 |
| K05760 | paxillin | 0 | 0 |
| K05762 | radixin | 0 | 0 |
| K05763 | moesin | 0 | 0 |
| K05859 | phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11] | 0 | 0 |
| K05860 | phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11] | 0 | 0 |
| K06106 | cortactin | 0 | 0 |
| K06225 | patched 1 | 0 | 0 |
| K06226 | smoothened | 0 | 0 |
| K06236 | collagen type I alpha | 0 | 0 |
| K06251 | vitronectin | 0 | 0 |
| K06255 | basement membrane-specific heparan sulfate proteoglycan core protein | 0 | 0 |
| K06256 | CD44 antigen | 0 | 0 |
| K06257 | syndecan 1 | 0 | 0 |
| K06269 | serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] | 0 | 0 |
| K06270 | protein phosphatase 1 regulatory subunit 12A | 0 | 0 |
| K06276 | 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1] | 0 | 0 |
| K06278 | caveolin 1 | 0 | 0 |
| K06481 | integrin alpha 2 | 0 | 0 |
| K06484 | integrin alpha 5 | 0 | 0 |
| K06487 | integrin alpha V | 0 | 0 |
| K06493 | integrin beta 3 | 0 | 0 |
| K06497 | CD63 antigen | 0 | 0 |
| K06588 | integrin beta 5 | 0 | 0 |
| K06625 | cyclin-dependent kinase inhibitor 1A | 0 | 0 |
| K06643 | E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27] | 0 | 0 |
| K07203 | serine/threonine-protein kinase mTOR [EC:2.7.11.1] | 0 | 0 |
| K07293 | tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48] | 0 | 0 |
| K07532 | Rho guanine nucleotide exchange factor 12 | 0 | 0 |
| K07827 | GTPase KRas | 0 | 0 |
| K07828 | GTPase NRas | 0 | 0 |
| K07829 | Ras-related protein R-Ras | 0 | 0 |
| K07830 | Ras-related protein R-Ras2 | 0 | 0 |
| K07831 | Ras-related protein M-Ras | 0 | 0 |
| K07964 | heparanase [EC:3.2.1.166] | 0 | 0 |
| K07965 | heparanase 2 [EC:3.2.1.-] | 0 | 0 |
| K08007 | ezrin | 0 | 0 |
| K08107 | glypican 1 | 0 | 0 |
| K08109 | glypican 3 | 0 | 0 |
| K08122 | lumican | 0 | 0 |
| K08268 | hypoxia-inducible factor 1 alpha | 0 | 0 |
| K08523 | heparin-binding EGF-like growth factor | 0 | 0 |
| K08550 | estrogen receptor alpha | 0 | 0 |
| K08845 | A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1] | 0 | 0 |
| K09069 | twist | 0 | 0 |
| K09108 | transcription factor AP-4 | 0 | 0 |
| K09295 | homrobox protein Hox-D10 | 0 | 0 |
| K09543 | heat shock protein beta-2 | 0 | 0 |
| K09593 | GRB2-associated-binding protein 1 | 0 | 0 |
| K10159 | toll-like receptor 2 | 0 | 0 |
| K10160 | toll-like receptor 4 | 0 | 0 |
| K10164 | homeobox protein Nanog | 0 | 0 |
| K10380 | ankyrin | 0 | 0 |
| K11988 | sonic hedgehog | 0 | 0 |
| K11989 | indian hedgehog | 0 | 0 |
| K12329 | protein phosphatase 1 regulatory subunit 12B | 0 | 0 |
| K12330 | Rho guanine nucleotide exchange factor 1 | 0 | 0 |
| K12461 | fibroblast growth factor receptor substrate 2 | 0 | 0 |
| K12823 | ATP-dependent RNA helicase DDX5/DBP2 [EC:3.6.4.13] | 0 | 0 |
| K12958 | caveolin 2 | 0 | 0 |
| K12959 | caveolin 3 | 0 | 0 |
| K13375 | transforming growth factor beta-1 | 0 | 0 |
| K13376 | transforming growth factor beta-2 | 0 | 0 |
| K13769 | insulin-like growth factor 2 | 0 | 0 |
| K16336 | syndecan 2 | 0 | 0 |
| K16338 | syndecan 4 | 0 | 0 |
| K16848 | Ras GTPase-activating-like protein IQGAP1 | 0 | 0 |
| K16857 | thrombospondin 1 | 0 | 0 |
| K16863 | microRNA 21 | 0 | 0 |
| K16864 | microRNA 10a | 0 | 0 |
| K16865 | programmed cell death protein 4 | 0 | 0 |
| K16866 | metalloproteinase inhibitor 3 | 0 | 0 |
| K16867 | NUDT16-like protein 1 | 0 | 0 |
| K17388 | Rho-associated protein kinase 2 [EC:2.7.11.1] | 0 | 0 |
| K17393 | microRNA 10b | 0 | 0 |
| K17457 | protein phosphatase 1 regulatory subunit 12C | 0 | 0 |
| K18497 | fibroblast growth factor 2 | 0 | 0 |
| K19662 | classical protein kinase C beta type [EC:2.7.11.13] | 0 | 0 |
| K19663 | classical protein kinase C gamma type [EC:2.7.11.13] | 0 | 0 |