Help to interpret the results
The page contains two contents:
General: this table lists the KO entries and their description specific to this pathway, and provides their frequencies in and in the whole dataset.
Profile + homologs: the distribution of the Kegg entries of Chagas disease Kegg pathway is displayed here. Given a Kegg entry and a genome, a red box indicates that one or more loci have been annotated with, while a green box indicates that no locus/loci has(have) been annotated with it, but it/they is/are part of an Orthologous group in which other members have been annotated with that Kegg entry, so it is likely that this copy(ies) also performs this Kegg function.
Check the composition of the Chagas disease pathway
| KO | Description | All occurrences |
|---|---|---|
| K00922 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153] | 0 |
| K01283 | peptidyl-dipeptidase A [EC:3.4.15.1] | 0 |
| K01354 | oligopeptidase B [EC:3.4.21.83] | 7 |
| K02373 | FAS-associated death domain protein | 0 |
| K02580 | nuclear factor NF-kappa-B p105 subunit | 0 |
| K02649 | phosphoinositide-3-kinase regulatory subunit alpha/beta/delta | 0 |
| K03156 | tumor necrosis factor superfamily, member 2 | 0 |
| K03158 | tumor necrosis factor receptor superfamily member 1A | 0 |
| K03175 | TNF receptor-associated factor 6 [EC:2.3.2.27] | 0 |
| K03456 | serine/threonine-protein phosphatase 2A regulatory subunit A | 0 |
| K03898 | kininogen | 0 |
| K03916 | bradykinin receptor B2 | 0 |
| K03982 | plasminogen activator inhibitor 1 | 0 |
| K03986 | complement C1q subcomponent subunit A | 0 |
| K03987 | complement C1q subcomponent subunit B | 0 |
| K03988 | complement C1q subcomponent subunit C | 0 |
| K03990 | complement component 3 | 0 |
| K04354 | serine/threonine-protein phosphatase 2A regulatory subunit B | 0 |
| K04371 | mitogen-activated protein kinase 1/3 [EC:2.7.11.24] | 0 |
| K04379 | proto-oncogene protein c-fos | 0 |
| K04382 | serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16] | 0 |
| K04388 | TGF-beta receptor type-2 [EC:2.7.11.30] | 0 |
| K04389 | tumor necrosis factor ligand superfamily member 6 | 0 |
| K04390 | tumor necrosis factor receptor superfamily member 6 | 0 |
| K04398 | caspase 8 [EC:3.4.22.61] | 0 |
| K04430 | mitogen-activated protein kinase kinase 4 [EC:2.7.12.2] | 0 |
| K04440 | mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24] | 0 |
| K04441 | p38 MAP kinase [EC:2.7.11.24] | 0 |
| K04448 | transcription factor AP-1 | 0 |
| K04456 | RAC serine/threonine-protein kinase [EC:2.7.11.1] | 0 |
| K04467 | inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10] | 0 |
| K04500 | mothers against decapentaplegic homolog 2 | 0 |
| K04519 | interleukin 1 beta | 0 |
| K04534 | guanine nucleotide-binding protein G(o) subunit alpha | 0 |
| K04630 | guanine nucleotide-binding protein G(i) subunit alpha | 0 |
| K04632 | guanine nucleotide-binding protein G(s) subunit alpha | 0 |
| K04633 | guanine nucleotide-binding protein G(olf) subunit alpha | 0 |
| K04634 | guanine nucleotide-binding protein G(q) subunit alpha | 0 |
| K04635 | guanine nucleotide-binding protein subunit alpha-11 | 0 |
| K04636 | guanine nucleotide-binding protein subunit alpha-14 | 0 |
| K04637 | guanine nucleotide-binding protein subunit alpha-15 | 0 |
| K04674 | TGF-beta receptor type-1 [EC:2.7.11.30] | 0 |
| K04687 | interferon gamma | 0 |
| K04724 | CASP8 and FADD-like apoptosis regulator | 0 |
| K04729 | myeloid differentiation primary response protein MyD88 | 0 |
| K04730 | interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1] | 0 |
| K04733 | interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1] | 0 |
| K04734 | NF-kappa-B inhibitor alpha | 0 |
| K04735 | transcription factor p65 | 0 |
| K05132 | interferon gamma receptor 1 | 0 |
| K05133 | interferon gamma receptor 2 | 0 |
| K05405 | interleukin 6 | 0 |
| K05406 | interleukin 12A | 0 |
| K05408 | C-C motif chemokine 3 | 0 |
| K05415 | interferon beta | 0 |
| K05425 | interleukin 12B | 0 |
| K05429 | interleukin 2 | 0 |
| K05443 | interleukin 10 | 0 |
| K05842 | toll-like receptor adapter molecule 1 | 0 |
| K05858 | phosphatidylinositol phospholipase C, beta [EC:3.1.4.11] | 0 |
| K06450 | T-cell surface glycoprotein CD3 delta chain | 0 |
| K06451 | T-cell surface glycoprotein CD3 epsilon chain | 0 |
| K06452 | T-cell surface glycoprotein CD3 gamma chain | 0 |
| K06453 | CD3Z antigen, zeta polypeptide | 0 |
| K07209 | inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10] | 0 |
| K07210 | inhibitor of nuclear factor kappa-B kinase subunit gamma | 0 |
| K08041 | adenylate cyclase 1 [EC:4.6.1.1] | 0 |
| K08057 | calreticulin | 0 |
| K08571 | cruzipain [EC:3.4.22.51] | 0 |
| K10030 | interleukin 8 | 0 |
| K10159 | toll-like receptor 2 | 0 |
| K10160 | toll-like receptor 4 | 0 |
| K10161 | toll-like receptor 9 | 0 |
| K10169 | toll-like receptor 6 | 0 |
| K10784 | T cell receptor alpha chain V region | 0 |
| K10785 | T-cell receptor beta chain V region | 0 |
| K12499 | C-C motif chemokine 5 | 0 |
| K13241 | nitric-oxide synthase, inducible [EC:1.14.13.39] | 0 |
| K13375 | transforming growth factor beta-1 | 0 |
| K13376 | transforming growth factor beta-2 | 0 |
| K13377 | transforming growth factor beta-3 | 0 |
| K13729 | thiol-dependent reductase 1 | 0 |
| K14624 | C-C motif chemokine 2 | 0 |
| K23590 | complement regulatory protein | 0 |
| K23591 | trans-sialidase [EC:3.2.1.-] | 0 |