Help to interpret the results
The page contains two contents:
General: this table lists the KO entries and their description specific to this pathway, and provides their frequencies in Morganella morganii S3 and in the whole dataset.
Profile + homologs: the distribution of the Kegg entries of Shigellosis Kegg pathway is displayed here. Given a Kegg entry and a genome, a red box indicates that one or more loci have been annotated with, while a green box indicates that no locus/loci has(have) been annotated with it, but it/they is/are part of an Orthologous group in which other members have been annotated with that Kegg entry, so it is likely that this copy(ies) also performs this Kegg function.
Check the composition of the Shigellosis pathway
| KO | Description | #in this genome | All occurrences |
|---|---|---|---|
| K00844 | hexokinase [EC:2.7.1.1] | 0 | 0 |
| K00914 | phosphatidylinositol 3-kinase [EC:2.7.1.137] | 0 | 0 |
| K00922 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153] | 0 | 0 |
| K01116 | phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11] | 0 | 0 |
| K01367 | calpain-1 [EC:3.4.22.52] | 0 | 0 |
| K01370 | caspase 1 [EC:3.4.22.36] | 0 | 0 |
| K02159 | apoptosis regulator BAX | 0 | 0 |
| K02161 | apoptosis regulator Bcl-2 | 0 | 0 |
| K02406 | flagellin | 2 | 15 |
| K02580 | nuclear factor NF-kappa-B p105 subunit | 0 | 0 |
| K02581 | NF-kappa-B inhibitor beta | 0 | 0 |
| K02649 | phosphoinositide-3-kinase regulatory subunit alpha/beta/delta | 0 | 0 |
| K02861 | receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1] | 0 | 0 |
| K02927 | ubiquitin-large subunit ribosomal protein L40e | 0 | 0 |
| K02977 | ubiquitin-small subunit ribosomal protein S27Ae | 0 | 0 |
| K03083 | glycogen synthase kinase 3 beta [EC:2.7.11.26] | 0 | 0 |
| K03094 | S-phase kinase-associated protein 1 | 0 | 0 |
| K03156 | tumor necrosis factor superfamily, member 2 | 0 | 0 |
| K03158 | tumor necrosis factor receptor superfamily member 1A | 0 | 0 |
| K03171 | tumor necrosis factor receptor type 1-associated DEATH domain protein | 0 | 0 |
| K03173 | TNF receptor-associated factor 2 [EC:2.3.2.27] | 0 | 0 |
| K03175 | TNF receptor-associated factor 6 [EC:2.3.2.27] | 0 | 0 |
| K03221 | type III secretion protein F | 0 | 2 |
| K03347 | cullin 1 | 0 | 0 |
| K03362 | F-box and WD-40 domain protein 1/11 | 0 | 0 |
| K03853 | calpain-2 [EC:3.4.22.53] | 0 | 0 |
| K03868 | E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32] | 0 | 0 |
| K03990 | complement component 3 | 0 | 0 |
| K04281 | calpastatin | 0 | 0 |
| K04361 | epidermal growth factor receptor [EC:2.7.10.1] | 0 | 0 |
| K04371 | mitogen-activated protein kinase 1/3 [EC:2.7.11.24] | 0 | 0 |
| K04386 | interleukin 1 receptor type I | 0 | 0 |
| K04391 | monocyte differentiation antigen CD14 | 0 | 0 |
| K04392 | Ras-related C3 botulinum toxin substrate 1 | 0 | 0 |
| K04393 | cell division control protein 42 | 0 | 0 |
| K04394 | caspase 4 [EC:3.4.22.57 3.4.22.64] | 0 | 0 |
| K04403 | TAK1-binding protein 1 | 0 | 0 |
| K04404 | TAK1-binding protein 2 | 0 | 0 |
| K04427 | mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25] | 0 | 0 |
| K04438 | C-crk adapter molecule crk | 0 | 0 |
| K04440 | mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24] | 0 | 0 |
| K04441 | p38 MAP kinase [EC:2.7.11.24] | 0 | 0 |
| K04445 | ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1] | 0 | 0 |
| K04448 | transcription factor AP-1 | 0 | 0 |
| K04451 | tumor protein p53 | 0 | 0 |
| K04456 | RAC serine/threonine-protein kinase [EC:2.7.11.1] | 0 | 0 |
| K04467 | inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10] | 0 | 0 |
| K04513 | Ras homolog gene family, member A | 0 | 0 |
| K04514 | Rho-associated protein kinase 1 [EC:2.7.11.1] | 0 | 0 |
| K04519 | interleukin 1 beta | 0 | 0 |
| K04551 | ubiquitin B | 0 | 0 |
| K04570 | Bcl-2-like 1 (apoptosis regulator Bcl-X) | 0 | 0 |
| K04688 | ribosomal protein S6 kinase beta [EC:2.7.11.1] | 0 | 0 |
| K04728 | serine-protein kinase ATM [EC:2.7.11.1] | 0 | 0 |
| K04729 | myeloid differentiation primary response protein MyD88 | 0 | 0 |
| K04734 | NF-kappa-B inhibitor alpha | 0 | 0 |
| K04735 | transcription factor p65 | 0 | 0 |
| K04958 | inositol 1,4,5-triphosphate receptor type 1 | 0 | 0 |
| K04959 | inositol 1,4,5-triphosphate receptor type 2 | 0 | 0 |
| K04960 | inositol 1,4,5-triphosphate receptor type 3 | 0 | 0 |
| K05410 | TANK-binding kinase 1 [EC:2.7.11.10] | 0 | 0 |
| K05411 | interferon regulatory factor 3 | 0 | 0 |
| K05415 | interferon beta | 0 | 0 |
| K05427 | granulocyte-macrophage colony-stimulating factor | 0 | 0 |
| K05482 | interleukin 18 | 0 | 0 |
| K05692 | actin beta/gamma 1 | 0 | 0 |
| K05699 | actinin alpha 1/4 | 0 | 0 |
| K05700 | vinculin | 0 | 0 |
| K05704 | tyrosine-protein kinase Src [EC:2.7.10.2] | 0 | 0 |
| K05719 | integrin beta 1 | 0 | 0 |
| K05725 | focal adhesion kinase 1 [EC:2.7.10.2] | 0 | 0 |
| K05726 | breast cancer anti-estrogen resistance 1 | 0 | 0 |
| K05740 | diaphanous 1 | 0 | 0 |
| K05748 | WAS protein family, member 2 | 0 | 0 |
| K05753 | WAS protein family, member 1 | 0 | 0 |
| K05754 | actin related protein 2/3 complex, subunit 5 | 0 | 0 |
| K05755 | actin related protein 2/3 complex, subunit 4 | 0 | 0 |
| K05756 | actin related protein 2/3 complex, subunit 3 | 0 | 0 |
| K05757 | actin related protein 2/3 complex, subunit 1A/1B | 0 | 0 |
| K05758 | actin related protein 2/3 complex, subunit 2 | 0 | 0 |
| K05759 | profilin | 0 | 0 |
| K05760 | paxillin | 0 | 0 |
| K05857 | phosphatidylinositol phospholipase C, delta [EC:3.1.4.11] | 0 | 0 |
| K05858 | phosphatidylinositol phospholipase C, beta [EC:3.1.4.11] | 0 | 0 |
| K05859 | phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11] | 0 | 0 |
| K05860 | phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11] | 0 | 0 |
| K05861 | phosphatidylinositol phospholipase C, zeta [EC:3.1.4.11] | 0 | 0 |
| K05862 | voltage-dependent anion channel protein 1 | 0 | 0 |
| K05864 | peptidyl-prolyl isomerase D [EC:5.2.1.8] | 0 | 0 |
| K06068 | novel protein kinase C delta type [EC:2.7.11.13] | 0 | 0 |
| K06106 | cortactin | 0 | 0 |
| K06256 | CD44 antigen | 0 | 0 |
| K06271 | talin | 0 | 0 |
| K06272 | integrin-linked kinase [EC:2.7.11.1] | 0 | 0 |
| K06484 | integrin alpha 5 | 0 | 0 |
| K06643 | E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27] | 0 | 0 |
| K06689 | ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23] | 0 | 0 |
| K07201 | forkhead box protein O1 | 0 | 0 |
| K07203 | serine/threonine-protein kinase mTOR [EC:2.7.11.1] | 0 | 0 |
| K07204 | regulatory associated protein of mTOR | 0 | 0 |
| K07209 | inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10] | 0 | 0 |
| K07210 | inhibitor of nuclear factor kappa-B kinase subunit gamma | 0 | 0 |
| K07345 | major type 1 subunit fimbrin (pilin) | 9 | 67 |
| K07368 | B-cell CLL/lymphoma 10 | 0 | 0 |
| K07369 | mucosa-associated lymphoid tissue lymphoma translocation protein 1 [EC:3.4.22.-] | 0 | 0 |
| K07937 | ADP-ribosylation factor 1/2 | 0 | 0 |
| K07941 | ADP-ribosylation factor 6 | 0 | 0 |
| K08333 | phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1] | 0 | 0 |
| K08334 | beclin | 0 | 0 |
| K08336 | ubiquitin-like protein ATG12 | 0 | 0 |
| K08339 | autophagy-related protein 5 | 0 | 0 |
| K08583 | calpain, small subunit 1 | 0 | 0 |
| K08727 | nucleotide-binding oligomerization domain-containing protein 1 | 0 | 0 |
| K08738 | cytochrome c | 0 | 0 |
| K08770 | ubiquitin C | 0 | 0 |
| K08822 | glycogen synthase kinase 3 alpha [EC:2.7.11.26] | 0 | 0 |
| K08846 | receptor-interacting serine/threonine-protein kinase 2 [EC:2.7.11.1] | 0 | 0 |
| K09408 | forkhead box protein O3 | 0 | 0 |
| K09849 | TNF receptor-associated factor 5 | 0 | 0 |
| K10030 | interleukin 8 | 0 | 0 |
| K10160 | toll-like receptor 4 | 0 | 0 |
| K10168 | toll-like receptor 5 | 0 | 0 |
| K10351 | myosin regulatory light chain 2 | 0 | 0 |
| K10435 | microtubule-associated protein 1 light chain | 0 | 0 |
| K10580 | ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23] | 0 | 0 |
| K10630 | RanBP-type and C3HC4-type zinc finger-containing protein 1 [EC:2.3.2.31] | 0 | 0 |
| K10704 | ubiquitin-conjugating enzyme E2 variant | 0 | 0 |
| K11006 | shiga toxin subunit A | 0 | 0 |
| K11007 | shiga toxin subunit B | 0 | 0 |
| K11011 | enterotoxin Set1A | 0 | 0 |
| K11012 | enterotoxin Set1B | 0 | 0 |
| K11253 | histone H3 | 0 | 0 |
| K11586 | chromobox protein 3 | 0 | 0 |
| K11974 | E3 ubiquitin-protein ligase RNF31 [EC:2.3.2.31] | 0 | 0 |
| K12358 | forkhead box protein O4 | 0 | 0 |
| K12366 | engulfment and cell motility protein 1 | 0 | 0 |
| K12499 | C-C motif chemokine 5 | 0 | 0 |
| K12654 | stimulator of interferon genes protein | 0 | 0 |
| K12679 | outer membrane protein IcsA | 0 | 0 |
| K12753 | myosin regulatory light chain 5 | 0 | 0 |
| K12754 | myosin regulatory light chain 7 | 0 | 0 |
| K12755 | myosin regulatory light chain 9 | 0 | 0 |
| K12756 | myosin regulatory light chain 10 | 0 | 0 |
| K12757 | myosin regulatory light chain 12 | 0 | 0 |
| K12758 | fast skeletal myosin light chain 2 | 0 | 0 |
| K12785 | LEE-encoded effector EspG | 0 | 0 |
| K12791 | Rho guanine nucleotide exchange factor 2 | 0 | 0 |
| K12793 | TAK1-binding protein 3 | 0 | 0 |
| K12799 | apoptosis-associated speck-like protein containing a CARD | 0 | 0 |
| K12800 | NACHT, LRR and PYD domains-containing protein 3 | 0 | 0 |
| K12805 | NLR family CARD domain-containing protein 4 | 0 | 0 |
| K12807 | baculoviral IAP repeat-containing protein 1 | 0 | 0 |
| K12836 | splicing factor U2AF 35 kDa subunit | 0 | 0 |
| K13085 | phosphatidylinositol-4,5-bisphosphate 4-phosphatase [EC:3.1.3.78] | 0 | 0 |
| K13284 | invasin A | 0 | 0 |
| K13285 | invasin B | 1 | 6 |
| K13286 | invasin C | 0 | 0 |
| K13287 | invasin D | 0 | 1 |
| K13450 | phosphothreonine lyase [EC:4.2.3.-] | 1 | 5 |
| K13520 | outer membrane protease [EC:3.4.23.-] | 0 | 0 |
| K13708 | dedicator of cytokinesis protein 1 | 0 | 0 |
| K13742 | protein IpgB1 | 0 | 0 |
| K13743 | protein IpgB2 | 0 | 0 |
| K13790 | virulence protein IcsB | 0 | 0 |
| K13791 | invasion plasmid antigen | 0 | 0 |
| K13792 | secreted effector OspG | 0 | 0 |
| K13793 | secreted effector OspE | 0 | 0 |
| K14381 | sequestosome 1 | 0 | 0 |
| K15464 | BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 | 0 | 0 |
| K16184 | proline-rich AKT1 substrate 1 | 0 | 0 |
| K16185 | Ras-related GTP-binding protein A/B | 0 | 0 |
| K16186 | Ras-related GTP-binding protein C/D | 0 | 0 |
| K16938 | septin 3/9/12 | 0 | 0 |
| K16939 | septin 6/8/11 | 0 | 0 |
| K16942 | septin 2 | 0 | 0 |
| K16944 | septin 7 | 0 | 0 |
| K17260 | actin-related protein 2 | 0 | 0 |
| K17388 | Rho-associated protein kinase 2 [EC:2.7.11.1] | 0 | 0 |
| K17834 | cyclic GMP-AMP synthase [EC:2.7.7.86] | 0 | 0 |
| K17847 | forkhead box protein O6 | 0 | 0 |
| K17889 | beclin 1-associated autophagy-related key regulator | 0 | 0 |
| K17890 | autophagy-related protein 16-1 | 0 | 0 |
| K17908 | autophagy-related protein 18 | 0 | 0 |
| K17988 | tectonin beta-propeller repeat-containing protein 1 | 0 | 0 |
| K18050 | novel protein kinase C epsilon type [EC:2.7.11.13] | 0 | 0 |
| K18052 | novel protein kinase C theta type [EC:2.7.11.13] | 0 | 0 |
| K18441 | cytohesin | 0 | 0 |
| K18584 | actin-related protein 3 | 0 | 0 |
| K18985 | engulfment and cell motility protein 2 | 0 | 0 |
| K20121 | formin-binding protein 1 | 0 | 0 |
| K20894 | shank-associated RH domain-interacting protein | 0 | 0 |
| K21348 | calcium-binding and coiled-coil domain-containing protein 2 | 0 | 0 |
| K22487 | type III secretion system protein | 0 | 1 |
| K23345 | glomulin | 0 | 0 |
| K23612 | neural Wiskott-Aldrich syndrome protein | 0 | 0 |
| K23654 | T3SS secreted effector NleE | 0 | 0 |
| K23826 | TRAF-interacting protein with FHA domain-containing protein A | 0 | 0 |
| K23827 | glutamine deamidase | 0 | 0 |
| K23828 | E3 ubiquitin-protein ligase IpaH1.4/2.5 [EC:2.3.2.27] | 0 | 0 |
| K23829 | TNFAIP3-interacting protein 1 | 0 | 0 |
| K23830 | E3 ubiquitin-protein ligase IpaH4.5 [EC:2.3.2.27] | 0 | 0 |
| K23831 | E3 ubiquitin-protein ligase IpaH0722 [EC:2.3.2.27] | 0 | 0 |
| K23832 | cysteine protease IpaJ [EC:3.4.22.-] | 0 | 0 |
| K23833 | secreted effector OspC | 0 | 0 |
| K23834 | E3 ubiquitin-protein ligase IpaH7.8 [EC:2.3.2.27] | 0 | 0 |