Huntington disease


Help to interpret the results


The page contains two contents:
General: this table lists the KO entries and their description specific to this pathway, and provides their frequencies in Proteus mirabilis HI4320 and in the whole dataset.
Profile + homologs: the distribution of the Kegg entries of Huntington disease Kegg pathway is displayed here. Given a Kegg entry and a genome, a red box indicates that one or more loci have been annotated with, while a green box indicates that no locus/loci has(have) been annotated with it, but it/they is/are part of an Orthologous group in which other members have been annotated with that Kegg entry, so it is likely that this copy(ies) also performs this Kegg function.

Check the composition of the Huntington disease pathway


KO Description #in this genome All occurrences
K00234 succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1] 0 0
K00235 succinate dehydrogenase (ubiquinone) iron-sulfur subunit [EC:1.3.5.1] 0 0
K00236 succinate dehydrogenase (ubiquinone) cytochrome b560 subunit 0 0
K00237 succinate dehydrogenase (ubiquinone) membrane anchor subunit 0 0
K00411 ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8] 0 0
K00412 ubiquinol-cytochrome c reductase cytochrome b subunit 0 0
K00413 ubiquinol-cytochrome c reductase cytochrome c1 subunit 0 0
K00414 ubiquinol-cytochrome c reductase core subunit 1 0 0
K00415 ubiquinol-cytochrome c reductase core subunit 2 0 0
K00416 ubiquinol-cytochrome c reductase subunit 6 0 0
K00417 ubiquinol-cytochrome c reductase subunit 7 0 0
K00418 ubiquinol-cytochrome c reductase subunit 8 0 0
K00419 ubiquinol-cytochrome c reductase subunit 9 0 0
K00420 ubiquinol-cytochrome c reductase subunit 10 0 0
K00432 glutathione peroxidase [EC:1.11.1.9] 0 0
K00914 phosphatidylinositol 3-kinase [EC:2.7.1.137] 0 0
K02084 apoptotic protease-activating factor 0 0
K02125 F-type H+-transporting ATPase subunit 8 0 0
K02126 F-type H+-transporting ATPase subunit a 0 0
K02127 F-type H+-transporting ATPase subunit b 0 0
K02128 F-type H+-transporting ATPase subunit c 0 0
K02131 F-type H+-transporting ATPase subunit 6 0 0
K02132 F-type H+-transporting ATPase subunit alpha 0 0
K02133 F-type H+-transporting ATPase subunit beta [EC:7.1.2.2] 0 0
K02134 F-type H+-transporting ATPase subunit delta 0 0
K02135 F-type H+-transporting ATPase subunit epsilon 0 0
K02136 F-type H+-transporting ATPase subunit gamma 0 0
K02137 F-type H+-transporting ATPase subunit O 0 0
K02138 F-type H+-transporting ATPase subunit d 0 0
K02159 apoptosis regulator BAX 0 0
K02187 caspase 3 [EC:3.4.22.56] 0 0
K02256 cytochrome c oxidase subunit 1 [EC:7.1.1.9] 0 0
K02261 cytochrome c oxidase subunit 2 0 0
K02262 cytochrome c oxidase subunit 3 0 0
K02263 cytochrome c oxidase subunit 4 0 0
K02264 cytochrome c oxidase subunit 5a 0 0
K02265 cytochrome c oxidase subunit 5b 0 0
K02266 cytochrome c oxidase subunit 6a 0 0
K02267 cytochrome c oxidase subunit 6b 0 0
K02268 cytochrome c oxidase subunit 6c 0 0
K02270 cytochrome c oxidase subunit 7a 0 0
K02271 cytochrome c oxidase subunit 7b 0 0
K02272 cytochrome c oxidase subunit 7c 0 0
K02273 cytochrome c oxidase subunit 8 0 0
K02725 20S proteasome subunit alpha 6 [EC:3.4.25.1] 0 0
K02726 20S proteasome subunit alpha 2 [EC:3.4.25.1] 0 0
K02727 20S proteasome subunit alpha 7 [EC:3.4.25.1] 0 0
K02728 20S proteasome subunit alpha 3 [EC:3.4.25.1] 0 0
K02729 20S proteasome subunit alpha 5 [EC:3.4.25.1] 0 0
K02730 20S proteasome subunit alpha 1 [EC:3.4.25.1] 0 0
K02731 20S proteasome subunit alpha 4 [EC:3.4.25.1] 0 0
K02732 20S proteasome subunit beta 6 [EC:3.4.25.1] 0 0
K02734 20S proteasome subunit beta 4 [EC:3.4.25.1] 0 0
K02735 20S proteasome subunit beta 3 [EC:3.4.25.1] 0 0
K02736 20S proteasome subunit beta 7 [EC:3.4.25.1] 0 0
K02737 20S proteasome subunit beta 5 [EC:3.4.25.1] 0 0
K02738 20S proteasome subunit beta 1 [EC:3.4.25.1] 0 0
K02739 20S proteasome subunit beta 2 [EC:3.4.25.1] 0 0
K03006 DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6] 0 0
K03007 DNA-directed RNA polymerases I, II, and III subunit RPABC5 0 0
K03008 DNA-directed RNA polymerase II subunit RPB11 0 0
K03009 DNA-directed RNA polymerases I, II, and III subunit RPABC4 0 0
K03010 DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6] 0 0
K03011 DNA-directed RNA polymerase II subunit RPB3 0 0
K03012 DNA-directed RNA polymerase II subunit RPB4 0 0
K03013 DNA-directed RNA polymerases I, II, and III subunit RPABC1 0 0
K03014 DNA-directed RNA polymerases I, II, and III subunit RPABC2 0 0
K03015 DNA-directed RNA polymerase II subunit RPB7 0 0
K03016 DNA-directed RNA polymerases I, II, and III subunit RPABC3 0 0
K03017 DNA-directed RNA polymerase II subunit RPB9 0 0
K03028 26S proteasome regulatory subunit N1 0 0
K03029 26S proteasome regulatory subunit N10 0 0
K03030 26S proteasome regulatory subunit N11 0 0
K03031 26S proteasome regulatory subunit N12 0 0
K03032 26S proteasome regulatory subunit N2 0 0
K03033 26S proteasome regulatory subunit N3 0 0
K03035 26S proteasome regulatory subunit N5 0 0
K03036 26S proteasome regulatory subunit N6 0 0
K03037 26S proteasome regulatory subunit N7 0 0
K03038 26S proteasome regulatory subunit N8 0 0
K03039 26S proteasome regulatory subunit N9 0 0
K03061 26S proteasome regulatory subunit T1 0 0
K03062 26S proteasome regulatory subunit T2 0 0
K03063 26S proteasome regulatory subunit T3 0 0
K03064 26S proteasome regulatory subunit T4 0 0
K03065 26S proteasome regulatory subunit T5 0 0
K03066 26S proteasome regulatory subunit T6 0 0
K03120 transcription initiation factor TFIID TATA-box-binding protein 0 0
K03129 transcription initiation factor TFIID subunit 4 0 0
K03173 TNF receptor-associated factor 2 [EC:2.3.2.27] 0 0
K03878 NADH-ubiquinone oxidoreductase chain 1 [EC:7.1.1.2] 0 0
K03879 NADH-ubiquinone oxidoreductase chain 2 [EC:7.1.1.2] 0 0
K03880 NADH-ubiquinone oxidoreductase chain 3 [EC:7.1.1.2] 0 0
K03881 NADH-ubiquinone oxidoreductase chain 4 [EC:7.1.1.2] 0 0
K03882 NADH-ubiquinone oxidoreductase chain 4L [EC:7.1.1.2] 0 0
K03883 NADH-ubiquinone oxidoreductase chain 5 [EC:7.1.1.2] 0 0
K03884 NADH-ubiquinone oxidoreductase chain 6 [EC:7.1.1.2] 0 0
K03934 NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:7.1.1.2] 0 0
K03935 NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:7.1.1.2] 0 0
K03936 NADH dehydrogenase (ubiquinone) Fe-S protein 3 [EC:7.1.1.2] 0 0
K03937 NADH dehydrogenase (ubiquinone) Fe-S protein 4 0 0
K03938 NADH dehydrogenase (ubiquinone) Fe-S protein 5 0 0
K03939 NADH dehydrogenase (ubiquinone) Fe-S protein 6 0 0
K03940 NADH dehydrogenase (ubiquinone) Fe-S protein 7 [EC:7.1.1.2] 0 0
K03941 NADH dehydrogenase (ubiquinone) Fe-S protein 8 [EC:7.1.1.2] 0 0
K03942 NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:7.1.1.2] 0 0
K03943 NADH dehydrogenase (ubiquinone) flavoprotein 2 [EC:7.1.1.2] 0 0
K03944 NADH dehydrogenase (ubiquinone) flavoprotein 3 0 0
K03945 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 1 0 0
K03946 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 2 0 0
K03947 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 3 0 0
K03948 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4 0 0
K03949 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 5 0 0
K03950 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 6 0 0
K03951 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 7 0 0
K03952 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 8 0 0
K03953 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 9 0 0
K03954 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 10 0 0
K03955 NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1, acyl-carrier protein 0 0
K03956 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 11 0 0
K03957 NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1 0 0
K03958 NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2 0 0
K03959 NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 3 0 0
K03960 NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 4 0 0
K03961 NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 5 0 0
K03962 NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 6 0 0
K03963 NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 7 0 0
K03964 NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 8 0 0
K03965 NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 9 0 0
K03966 NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 10 0 0
K03967 NADH dehydrogenase (ubiquinone) 1 subunit C1 0 0
K03968 NADH dehydrogenase (ubiquinone) 1 subunit C2 0 0
K04355 brain-derived neurotrophic factor 0 0
K04398 caspase 8 [EC:3.4.22.61] 0 0
K04399 caspase 9 [EC:3.4.22.62] 0 0
K04418 mitogen-activated protein kinase kinase kinase 10 [EC:2.7.11.25] 0 0
K04426 mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25] 0 0
K04431 mitogen-activated protein kinase kinase 7 [EC:2.7.12.2] 0 0
K04440 mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24] 0 0
K04451 tumor protein p53 0 0
K04498 E1A/CREB-binding protein [EC:2.3.1.48] 0 0
K04533 huntingtin 0 0
K04559 huntingtin interacting protein 1 0 0
K04560 syntaxin 1A 0 0
K04564 superoxide dismutase, Fe-Mn family [EC:1.15.1.1] 2 14
K04565 superoxide dismutase, Cu-Zn family [EC:1.15.1.1] 1 6
K04604 metabotropic glutamate receptor 5 0 0
K04634 guanine nucleotide-binding protein G(q) subunit alpha 0 0
K04638 intraflagellar transport protein 57 0 0
K04644 clathrin light chain A 0 0
K04645 clathrin light chain B 0 0
K04646 clathrin heavy chain 0 0
K04647 huntingtin-associated protein 1 0 0
K04648 dynactin 1 0 0
K04684 transcription factor Sp1 0 0
K04849 voltage-dependent calcium channel N type alpha-1B 0 0
K04958 inositol 1,4,5-triphosphate receptor type 1 0 0
K05003 potassium inwardly-rectifying channel subfamily J member 10 0 0
K05197 glutamate receptor 1 0 0
K05198 glutamate receptor 2 0 0
K05199 glutamate receptor 3 0 0
K05200 glutamate receptor 4 0 0
K05208 glutamate receptor ionotropic, NMDA 1 0 0
K05210 glutamate receptor ionotropic, NMDA 2B 0 0
K05613 solute carrier family 1 (glial high affinity glutamate transporter), member 2 0 0
K05614 solute carrier family 1 (glial high affinity glutamate transporter), member 3 0 0
K05625 transglutaminase 2 [EC:2.3.2.13] 0 0
K05858 phosphatidylinositol phospholipase C, beta [EC:3.1.4.11] 0 0
K05862 voltage-dependent anion channel protein 1 0 0
K05863 solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31 0 0
K05870 cyclic AMP-responsive element-binding protein 1 0 0
K06067 histone deacetylase 1/2 [EC:3.5.1.98] 0 0
K06691 26S proteasome regulatory subunit N13 0 0
K06693 26S proteasome regulatory subunit N4 0 0
K07202 alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha 0 0
K07203 serine/threonine-protein kinase mTOR [EC:2.7.11.1] 0 0
K07374 tubulin alpha 0 0
K07375 tubulin beta 0 0
K08269 serine/threonine-protein kinase ULK2 [EC:2.7.11.1] 0 0
K08331 autophagy-related protein 13 0 0
K08333 phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1] 0 0
K08334 beclin 0 0
K08530 peroxisome proliferator-activated receptor gamma 0 0
K08738 cytochrome c 0 0
K08769 solute carrier family 25 (mitochondrial uncoupling protein), member 7 0 0
K08852 serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-] 0 0
K09047 cyclic AMP-responsive element-binding protein 5 0 0
K09048 cyclic AMP-responsive element-binding protein 3 0 0
K09222 RE1-silencing transcription factor 0 0
K09565 peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8] 0 0
K10132 Bcl-2-binding component 3 0 0
K10396 kinesin family member 5 0 0
K10407 kinesin light chain 0 0
K10408 dynein axonemal heavy chain 0 0
K10409 dynein axonemal intermediate chain 1 0 0
K10410 dynein axonemal light intermediate chain 1 0 0
K10411 dynein axonemal light chain 1 0 0
K10412 dynein axonemal light chain 4 0 0
K10424 dynactin 2 0 0
K10425 dynactin 3 0 0
K10426 dynactin 4 0 0
K10427 dynactin 5 0 0
K10428 dynactin 6 0 0
K10881 26 proteasome complex subunit DSS1 0 0
K11143 dynein axonemal intermediate chain 2 0 0
K11351 NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11 0 0
K11352 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 12 0 0
K11353 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 13 0 0
K11644 paired amphipathic helix protein Sin3a 0 0
K11824 AP-2 complex subunit alpha 0 0
K11825 AP-2 complex subunit beta-1 0 0
K11826 AP-2 complex subunit mu-1 0 0
K11827 AP-2 complex subunit sigma-1 0 0
K11828 discs large protein 4 0 0
K11829 REST corepressor 1 0 0
K11830 transcription factor A, mitochondrial 0 0
K11831 nuclear respiratory factor 1 0 0
K15040 voltage-dependent anion channel protein 2 0 0
K15041 voltage-dependent anion channel protein 3 0 0
K16575 centractin 0 0
K16576 actin-related protein 10 0 0
K17589 RB1-inducible coiled-coil protein 1 0 0
K17889 beclin 1-associated autophagy-related key regulator 0 0
K17906 autophagy-related protein 2 0 0
K17908 autophagy-related protein 18 0 0
K17985 activating molecule in BECN1-regulated autophagy protein 1 0 0
K19730 autophagy-related protein 101 0 0
K21246 nuclear receptor-binding factor 2 0 0
K21357 serine/threonine-protein kinase ULK1 [EC:2.7.11.1] 0 0