Parkinson disease


Help to interpret the results


The page contains two contents:
General: this table lists the KO entries and their description specific to this pathway, and provides their frequencies in Morganella morganii S1 and in the whole dataset.
Profile + homologs: the distribution of the Kegg entries of Parkinson disease Kegg pathway is displayed here. Given a Kegg entry and a genome, a red box indicates that one or more loci have been annotated with, while a green box indicates that no locus/loci has(have) been annotated with it, but it/they is/are part of an Orthologous group in which other members have been annotated with that Kegg entry, so it is likely that this copy(ies) also performs this Kegg function.

Check the composition of the Parkinson disease pathway


KO Description #in this genome All occurrences
K00234 succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1] 0 0
K00235 succinate dehydrogenase (ubiquinone) iron-sulfur subunit [EC:1.3.5.1] 0 0
K00236 succinate dehydrogenase (ubiquinone) cytochrome b560 subunit 0 0
K00237 succinate dehydrogenase (ubiquinone) membrane anchor subunit 0 0
K00274 monoamine oxidase [EC:1.4.3.4] 0 0
K00411 ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8] 0 0
K00412 ubiquinol-cytochrome c reductase cytochrome b subunit 0 0
K00413 ubiquinol-cytochrome c reductase cytochrome c1 subunit 0 0
K00414 ubiquinol-cytochrome c reductase core subunit 1 0 0
K00415 ubiquinol-cytochrome c reductase core subunit 2 0 0
K00416 ubiquinol-cytochrome c reductase subunit 6 0 0
K00417 ubiquinol-cytochrome c reductase subunit 7 0 0
K00418 ubiquinol-cytochrome c reductase subunit 8 0 0
K00419 ubiquinol-cytochrome c reductase subunit 9 0 0
K00420 ubiquinol-cytochrome c reductase subunit 10 0 0
K00501 tyrosine 3-monooxygenase [EC:1.14.16.2] 0 0
K01116 phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11] 0 0
K02084 apoptotic protease-activating factor 0 0
K02125 F-type H+-transporting ATPase subunit 8 0 0
K02126 F-type H+-transporting ATPase subunit a 0 0
K02127 F-type H+-transporting ATPase subunit b 0 0
K02128 F-type H+-transporting ATPase subunit c 0 0
K02131 F-type H+-transporting ATPase subunit 6 0 0
K02132 F-type H+-transporting ATPase subunit alpha 0 0
K02133 F-type H+-transporting ATPase subunit beta [EC:7.1.2.2] 0 0
K02134 F-type H+-transporting ATPase subunit delta 0 0
K02135 F-type H+-transporting ATPase subunit epsilon 0 0
K02136 F-type H+-transporting ATPase subunit gamma 0 0
K02137 F-type H+-transporting ATPase subunit O 0 0
K02138 F-type H+-transporting ATPase subunit d 0 0
K02159 apoptosis regulator BAX 0 0
K02183 calmodulin 0 0
K02187 caspase 3 [EC:3.4.22.56] 0 0
K02256 cytochrome c oxidase subunit 1 [EC:7.1.1.9] 0 0
K02261 cytochrome c oxidase subunit 2 0 0
K02262 cytochrome c oxidase subunit 3 0 0
K02263 cytochrome c oxidase subunit 4 0 0
K02264 cytochrome c oxidase subunit 5a 0 0
K02265 cytochrome c oxidase subunit 5b 0 0
K02266 cytochrome c oxidase subunit 6a 0 0
K02267 cytochrome c oxidase subunit 6b 0 0
K02268 cytochrome c oxidase subunit 6c 0 0
K02270 cytochrome c oxidase subunit 7a 0 0
K02271 cytochrome c oxidase subunit 7b 0 0
K02272 cytochrome c oxidase subunit 7c 0 0
K02273 cytochrome c oxidase subunit 8 0 0
K02308 death-associated protein 6 0 0
K02725 20S proteasome subunit alpha 6 [EC:3.4.25.1] 0 0
K02726 20S proteasome subunit alpha 2 [EC:3.4.25.1] 0 0
K02727 20S proteasome subunit alpha 7 [EC:3.4.25.1] 0 0
K02728 20S proteasome subunit alpha 3 [EC:3.4.25.1] 0 0
K02729 20S proteasome subunit alpha 5 [EC:3.4.25.1] 0 0
K02730 20S proteasome subunit alpha 1 [EC:3.4.25.1] 0 0
K02731 20S proteasome subunit alpha 4 [EC:3.4.25.1] 0 0
K02732 20S proteasome subunit beta 6 [EC:3.4.25.1] 0 0
K02734 20S proteasome subunit beta 4 [EC:3.4.25.1] 0 0
K02735 20S proteasome subunit beta 3 [EC:3.4.25.1] 0 0
K02736 20S proteasome subunit beta 7 [EC:3.4.25.1] 0 0
K02737 20S proteasome subunit beta 5 [EC:3.4.25.1] 0 0
K02738 20S proteasome subunit beta 1 [EC:3.4.25.1] 0 0
K02739 20S proteasome subunit beta 2 [EC:3.4.25.1] 0 0
K02927 ubiquitin-large subunit ribosomal protein L40e 0 0
K02977 ubiquitin-small subunit ribosomal protein S27Ae 0 0
K03028 26S proteasome regulatory subunit N1 0 0
K03029 26S proteasome regulatory subunit N10 0 0
K03030 26S proteasome regulatory subunit N11 0 0
K03031 26S proteasome regulatory subunit N12 0 0
K03032 26S proteasome regulatory subunit N2 0 0
K03033 26S proteasome regulatory subunit N3 0 0
K03035 26S proteasome regulatory subunit N5 0 0
K03036 26S proteasome regulatory subunit N6 0 0
K03037 26S proteasome regulatory subunit N7 0 0
K03038 26S proteasome regulatory subunit N8 0 0
K03039 26S proteasome regulatory subunit N9 0 0
K03061 26S proteasome regulatory subunit T1 0 0
K03062 26S proteasome regulatory subunit T2 0 0
K03063 26S proteasome regulatory subunit T3 0 0
K03064 26S proteasome regulatory subunit T4 0 0
K03065 26S proteasome regulatory subunit T5 0 0
K03066 26S proteasome regulatory subunit T6 0 0
K03178 ubiquitin-activating enzyme E1 [EC:6.2.1.45] 0 0
K03237 translation initiation factor 2 subunit 1 0 0
K03671 thioredoxin 1 7
K03878 NADH-ubiquinone oxidoreductase chain 1 [EC:7.1.1.2] 0 0
K03879 NADH-ubiquinone oxidoreductase chain 2 [EC:7.1.1.2] 0 0
K03880 NADH-ubiquinone oxidoreductase chain 3 [EC:7.1.1.2] 0 0
K03881 NADH-ubiquinone oxidoreductase chain 4 [EC:7.1.1.2] 0 0
K03882 NADH-ubiquinone oxidoreductase chain 4L [EC:7.1.1.2] 0 0
K03883 NADH-ubiquinone oxidoreductase chain 5 [EC:7.1.1.2] 0 0
K03884 NADH-ubiquinone oxidoreductase chain 6 [EC:7.1.1.2] 0 0
K03934 NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:7.1.1.2] 0 0
K03935 NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:7.1.1.2] 0 0
K03936 NADH dehydrogenase (ubiquinone) Fe-S protein 3 [EC:7.1.1.2] 0 0
K03937 NADH dehydrogenase (ubiquinone) Fe-S protein 4 0 0
K03938 NADH dehydrogenase (ubiquinone) Fe-S protein 5 0 0
K03939 NADH dehydrogenase (ubiquinone) Fe-S protein 6 0 0
K03940 NADH dehydrogenase (ubiquinone) Fe-S protein 7 [EC:7.1.1.2] 0 0
K03941 NADH dehydrogenase (ubiquinone) Fe-S protein 8 [EC:7.1.1.2] 0 0
K03942 NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:7.1.1.2] 0 0
K03943 NADH dehydrogenase (ubiquinone) flavoprotein 2 [EC:7.1.1.2] 0 0
K03944 NADH dehydrogenase (ubiquinone) flavoprotein 3 0 0
K03945 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 1 0 0
K03946 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 2 0 0
K03947 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 3 0 0
K03948 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4 0 0
K03949 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 5 0 0
K03950 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 6 0 0
K03951 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 7 0 0
K03952 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 8 0 0
K03953 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 9 0 0
K03954 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 10 0 0
K03955 NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1, acyl-carrier protein 0 0
K03956 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 11 0 0
K03957 NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1 0 0
K03958 NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2 0 0
K03959 NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 3 0 0
K03960 NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 4 0 0
K03961 NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 5 0 0
K03962 NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 6 0 0
K03963 NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 7 0 0
K03964 NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 8 0 0
K03965 NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 9 0 0
K03966 NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 10 0 0
K03967 NADH dehydrogenase (ubiquinone) 1 subunit C1 0 0
K03968 NADH dehydrogenase (ubiquinone) 1 subunit C2 0 0
K04144 dopamine receptor D1 0 0
K04145 dopamine receptor D2 0 0
K04243 prosaposin receptor 0 0
K04266 adenosine receptor A2a 0 0
K04345 protein kinase A [EC:2.7.11.11] 0 0
K04374 cyclic AMP-dependent transcription factor ATF-4 0 0
K04380 microtubule-associated protein tau 0 0
K04399 caspase 9 [EC:3.4.22.62] 0 0
K04426 mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25] 0 0
K04440 mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24] 0 0
K04451 tumor protein p53 0 0
K04452 DNA damage-inducible transcript 3 0 0
K04515 calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17] 0 0
K04528 alpha-synuclein 0 0
K04551 ubiquitin B 0 0
K04552 ubiquitin-conjugating enzyme E2 L3 [EC:2.3.2.23] 0 0
K04553 ubiquitin/ISG15-conjugating enzyme E2 L6 [EC:2.3.2.23] 0 0
K04554 ubiquitin-conjugating enzyme E2 J2 [EC:2.3.2.23] 0 0
K04555 ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23] 0 0
K04556 parkin [EC:2.3.2.31] 0 0
K04557 septin 5 0 0
K04558 synphilin-1 0 0
K04565 superoxide dismutase, Cu-Zn family [EC:1.15.1.1] 1 6
K04570 Bcl-2-like 1 (apoptosis regulator Bcl-X) 0 0
K04630 guanine nucleotide-binding protein G(i) subunit alpha 0 0
K04632 guanine nucleotide-binding protein G(s) subunit alpha 0 0
K04633 guanine nucleotide-binding protein G(olf) subunit alpha 0 0
K04958 inositol 1,4,5-triphosphate receptor type 1 0 0
K04959 inositol 1,4,5-triphosphate receptor type 2 0 0
K04960 inositol 1,4,5-triphosphate receptor type 3 0 0
K04963 ryanodine receptor 3 0 0
K05036 solute carrier family 6 (neurotransmitter transporter, dopamine) member 3 0 0
K05611 ubiquitin carboxyl-terminal hydrolase L1 [EC:3.4.19.12] 0 0
K05638 nuclear factor erythroid 2-related factor 2 0 0
K05687 protein DJ-1 [EC:3.5.1.124] 0 0
K05688 PTEN induced putative kinase 1 [EC:2.7.11.1] 0 0
K05862 voltage-dependent anion channel protein 1 0 0
K05863 solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31 0 0
K06030 mitofusin 2 [EC:3.6.5.-] 0 0
K06691 26S proteasome regulatory subunit N13 0 0
K06693 26S proteasome regulatory subunit N4 0 0
K07374 tubulin alpha 0 0
K07375 tubulin beta 0 0
K08045 adenylate cyclase 5 [EC:4.6.1.1] 0 0
K08155 MFS transporter, DHA1 family, solute carrier family 18 (vesicular amine transporter), member 1/2 0 0
K08669 HtrA serine peptidase 2 [EC:3.4.21.108] 0 0
K08738 cytochrome c 0 0
K08770 ubiquitin C 0 0
K08844 leucine-rich repeat kinase 2 [EC:2.7.11.1] 0 0
K08852 serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-] 0 0
K08860 eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1] 0 0
K09027 X box-binding protein 1 0 0
K09054 cyclic AMP-dependent transcription factor ATF-6 alpha 0 0
K09488 TNF receptor-associated protein 1 0 0
K09490 endoplasmic reticulum chaperone BiP [EC:3.6.4.10] 0 0
K09565 peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8] 0 0
K10396 kinesin family member 5 0 0
K10407 kinesin light chain 0 0
K10456 kelch-like protein 19 0 0
K10575 ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23] 0 0
K10578 ubiquitin-conjugating enzyme E2 J1 [EC:2.3.2.23] 0 0
K10698 ubiquitin-activating enzyme E1-like [EC:6.2.1.45] 0 0
K10881 26 proteasome complex subunit DSS1 0 0
K11351 NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11 0 0
K11352 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 12 0 0
K11353 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 13 0 0
K14709 solute carrier family 39 (zinc transporter), member 1/2/3 0 0
K14710 solute carrier family 39 (zinc transporter), member 4 0 0
K14711 solute carrier family 39 (zinc transporter), member 5 0 0
K14712 solute carrier family 39 (zinc transporter), member 6 0 0
K14713 solute carrier family 39 (zinc transporter), member 7 0 0
K14714 solute carrier family 39 (zinc transporter), member 8 0 0
K14715 solute carrier family 39 (zinc transporter), member 9 0 0
K14716 solute carrier family 39 (zinc transporter), member 10 0 0
K14717 solute carrier family 39 (zinc transporter), member 11 0 0
K14718 solute carrier family 39 (zinc transporter), member 12 0 0
K14719 solute carrier family 39 (zinc transporter), member 13 0 0
K14720 solute carrier family 39 (zinc transporter), member 14 0 0
K15040 voltage-dependent anion channel protein 2 0 0
K15041 voltage-dependent anion channel protein 3 0 0
K20858 calcium uniporter protein, mitochondrial 0 0
K21278 dual specificity protein phosphatase 1 [EC:3.1.3.16 3.1.3.48] 0 0
K21356 mitofusin 1 [EC:3.6.5.-] 0 0
K21398 natural resistance-associated macrophage protein 2 0 0