Help to interpret the results
The page contains two contents:
General: this table lists the KO entries and their description specific to this pathway, and provides their frequencies in Proteus mirabilis HI4320 and in the whole dataset.
Profile + homologs: the distribution of the Kegg entries of Alcoholic liver disease Kegg pathway is displayed here. Given a Kegg entry and a genome, a red box indicates that one or more loci have been annotated with, while a green box indicates that no locus/loci has(have) been annotated with it, but it/they is/are part of an Orthologous group in which other members have been annotated with that Kegg entry, so it is likely that this copy(ies) also performs this Kegg function.
Check the composition of the Alcoholic liver disease pathway
| KO | Description | #in this genome | All occurrences |
|---|---|---|---|
| K00121 | S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1] | 1 | 7 |
| K00128 | aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] | 1 | 7 |
| K00149 | aldehyde dehydrogenase family 9 member A1 [EC:1.2.1.47 1.2.1.3] | 0 | 0 |
| K00232 | acyl-CoA oxidase [EC:1.3.3.6] | 0 | 0 |
| K00249 | acyl-CoA dehydrogenase [EC:1.3.8.7] | 0 | 0 |
| K00507 | stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1] | 0 | 0 |
| K00665 | fatty acid synthase, animal type [EC:2.3.1.85] | 0 | 0 |
| K01332 | complement component 2 [EC:3.4.21.43] | 0 | 0 |
| K01578 | malonyl-CoA decarboxylase [EC:4.1.1.9] | 0 | 0 |
| K01946 | acetyl-CoA carboxylase / biotin carboxylase 2 [EC:6.4.1.2 6.3.4.14 2.1.3.15] | 0 | 0 |
| K02105 | catenin beta 1 | 0 | 0 |
| K02187 | caspase 3 [EC:3.4.22.56] | 0 | 0 |
| K02373 | FAS-associated death domain protein | 0 | 0 |
| K02580 | nuclear factor NF-kappa-B p105 subunit | 0 | 0 |
| K02620 | transcription factor 7 | 0 | 0 |
| K02861 | receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1] | 0 | 0 |
| K03083 | glycogen synthase kinase 3 beta [EC:2.7.11.26] | 0 | 0 |
| K03156 | tumor necrosis factor superfamily, member 2 | 0 | 0 |
| K03158 | tumor necrosis factor receptor superfamily member 1A | 0 | 0 |
| K03171 | tumor necrosis factor receptor type 1-associated DEATH domain protein | 0 | 0 |
| K03174 | TNF receptor-associated factor 3 | 0 | 0 |
| K03175 | TNF receptor-associated factor 6 [EC:2.3.2.27] | 0 | 0 |
| K03986 | complement C1q subcomponent subunit A | 0 | 0 |
| K03987 | complement C1q subcomponent subunit B | 0 | 0 |
| K03988 | complement C1q subcomponent subunit C | 0 | 0 |
| K03989 | complement component 4 | 0 | 0 |
| K03990 | complement component 3 | 0 | 0 |
| K03994 | complement component 5 | 0 | 0 |
| K04009 | C3a anaphylatoxin chemotactic receptor | 0 | 0 |
| K04010 | C5a anaphylatoxin chemotactic receptor 1 | 0 | 0 |
| K04389 | tumor necrosis factor ligand superfamily member 6 | 0 | 0 |
| K04390 | tumor necrosis factor receptor superfamily member 6 | 0 | 0 |
| K04391 | monocyte differentiation antigen CD14 | 0 | 0 |
| K04398 | caspase 8 [EC:3.4.22.61] | 0 | 0 |
| K04403 | TAK1-binding protein 1 | 0 | 0 |
| K04404 | TAK1-binding protein 2 | 0 | 0 |
| K04426 | mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25] | 0 | 0 |
| K04427 | mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25] | 0 | 0 |
| K04430 | mitogen-activated protein kinase kinase 4 [EC:2.7.12.2] | 0 | 0 |
| K04431 | mitogen-activated protein kinase kinase 7 [EC:2.7.12.2] | 0 | 0 |
| K04432 | mitogen-activated protein kinase kinase 3 [EC:2.7.12.2] | 0 | 0 |
| K04433 | mitogen-activated protein kinase kinase 6 [EC:2.7.12.2] | 0 | 0 |
| K04440 | mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24] | 0 | 0 |
| K04441 | p38 MAP kinase [EC:2.7.11.24] | 0 | 0 |
| K04456 | RAC serine/threonine-protein kinase [EC:2.7.11.1] | 0 | 0 |
| K04466 | mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25] | 0 | 0 |
| K04467 | inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10] | 0 | 0 |
| K04490 | transcription factor 7-like 1 | 0 | 0 |
| K04491 | transcription factor 7-like 2 | 0 | 0 |
| K04492 | lymphoid enhancer-binding factor 1 | 0 | 0 |
| K04503 | G1/S-specific cyclin-D1 | 0 | 0 |
| K04519 | interleukin 1 beta | 0 | 0 |
| K04729 | myeloid differentiation primary response protein MyD88 | 0 | 0 |
| K04730 | interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1] | 0 | 0 |
| K04733 | interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1] | 0 | 0 |
| K04734 | NF-kappa-B inhibitor alpha | 0 | 0 |
| K04735 | transcription factor p65 | 0 | 0 |
| K05164 | interleukin 17 receptor A | 0 | 0 |
| K05166 | interleukin 17 receptor C | 0 | 0 |
| K05399 | lipopolysaccharide-binding protein | 0 | 0 |
| K05400 | lymphocyte antigen 96 | 0 | 0 |
| K05403 | toll-interleukin 1 receptor (TIR) domain-containing adaptor protein | 0 | 0 |
| K05405 | interleukin 6 | 0 | 0 |
| K05406 | interleukin 12A | 0 | 0 |
| K05410 | TANK-binding kinase 1 [EC:2.7.11.10] | 0 | 0 |
| K05411 | interferon regulatory factor 3 | 0 | 0 |
| K05414 | interferon alpha | 0 | 0 |
| K05415 | interferon beta | 0 | 0 |
| K05425 | interleukin 12B | 0 | 0 |
| K05489 | interleukin 17A | 0 | 0 |
| K05505 | C-X-C motif chemokine 1/2/3 | 0 | 0 |
| K05842 | toll-like receptor adapter molecule 1 | 0 | 0 |
| K07197 | sterol regulatory element-binding transcription factor 1 | 0 | 0 |
| K07198 | 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31] | 0 | 0 |
| K07199 | 5'-AMP-activated protein kinase, regulatory beta subunit | 0 | 0 |
| K07200 | 5'-AMP-activated protein kinase, regulatory gamma subunit | 0 | 0 |
| K07201 | forkhead box protein O1 | 0 | 0 |
| K07202 | alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha | 0 | 0 |
| K07209 | inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10] | 0 | 0 |
| K07210 | inhibitor of nuclear factor kappa-B kinase subunit gamma | 0 | 0 |
| K07211 | inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10] | 0 | 0 |
| K07294 | peroxisome proliferator-activated receptor alpha | 0 | 0 |
| K07296 | adiponectin | 0 | 0 |
| K07297 | adiponectin receptor | 0 | 0 |
| K07359 | calcium/calmodulin-dependent protein kinase kinase 2 [EC:2.7.11.17] | 0 | 0 |
| K07415 | cytochrome P450 family 2 subfamily E1 [EC:1.14.14.-] | 0 | 0 |
| K08750 | fatty acid-binding protein 1, liver | 0 | 0 |
| K08765 | carnitine O-palmitoyltransferase 1, liver isoform [EC:2.3.1.21] | 0 | 0 |
| K09408 | forkhead box protein O3 | 0 | 0 |
| K09479 | very long chain acyl-CoA dehydrogenase [EC:1.3.8.9] | 0 | 0 |
| K10030 | interleukin 8 | 0 | 0 |
| K10160 | toll-like receptor 4 | 0 | 0 |
| K11262 | acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14 2.1.3.15] | 0 | 0 |
| K11411 | NAD-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286] | 0 | 0 |
| K12793 | TAK1-binding protein 3 | 0 | 0 |
| K12897 | transformer-2 protein | 0 | 0 |
| K13951 | alcohol dehydrogenase 1/7 [EC:1.1.1.1] | 0 | 0 |
| K13952 | alcohol dehydrogenase 6 [EC:1.1.1.1] | 0 | 0 |
| K13980 | alcohol dehydrogenase 4 [EC:1.1.1.1] | 0 | 0 |
| K14085 | aldehyde dehydrogenase family 7 member A1 [EC:1.2.1.31 1.2.1.8 1.2.1.3] | 0 | 0 |
| K15728 | phosphatidate phosphatase LPIN [EC:3.1.3.4] | 0 | 0 |
| K17125 | microRNA 217 | 0 | 0 |
| K19523 | carnitine O-palmitoyltransferase 1, muscle isoform [EC:2.3.1.21] | 0 | 0 |
| K19524 | carnitine O-palmitoyltransferase 1, brain isoform [EC:2.3.1.21] | 0 | 0 |
| K21423 | NADPH oxidase 4 [EC:1.6.3.-] | 0 | 0 |