Help to interpret the results
The page contains two contents:
General: this table lists the KO entries and their description specific to this pathway, and provides their frequencies in Morganella morganii S5 and in the whole dataset.
Profile + homologs: the distribution of the Kegg entries of Insulin resistance Kegg pathway is displayed here. Given a Kegg entry and a genome, a red box indicates that one or more loci have been annotated with, while a green box indicates that no locus/loci has(have) been annotated with it, but it/they is/are part of an Orthologous group in which other members have been annotated with that Kegg entry, so it is likely that this copy(ies) also performs this Kegg function.
Check the composition of the Insulin resistance pathway
| KO | Description | #in this genome | All occurrences |
|---|---|---|---|
| K00688 | glycogen phosphorylase [EC:2.4.1.1] | 0 | 0 |
| K00693 | glycogen synthase [EC:2.4.1.11] | 0 | 0 |
| K00820 | glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] | 1 | 7 |
| K00922 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153] | 0 | 0 |
| K01084 | glucose-6-phosphatase [EC:3.1.3.9] | 0 | 0 |
| K01110 | phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67] | 0 | 0 |
| K01596 | phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32] | 0 | 0 |
| K01946 | acetyl-CoA carboxylase / biotin carboxylase 2 [EC:6.4.1.2 6.3.4.14 2.1.3.15] | 0 | 0 |
| K02580 | nuclear factor NF-kappa-B p105 subunit | 0 | 0 |
| K02649 | phosphoinositide-3-kinase regulatory subunit alpha/beta/delta | 0 | 0 |
| K03083 | glycogen synthase kinase 3 beta [EC:2.7.11.26] | 0 | 0 |
| K03156 | tumor necrosis factor superfamily, member 2 | 0 | 0 |
| K03158 | tumor necrosis factor receptor superfamily member 1A | 0 | 0 |
| K04373 | ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1] | 0 | 0 |
| K04440 | mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24] | 0 | 0 |
| K04456 | RAC serine/threonine-protein kinase [EC:2.7.11.1] | 0 | 0 |
| K04526 | insulin | 0 | 0 |
| K04527 | insulin receptor [EC:2.7.10.1] | 0 | 0 |
| K04688 | ribosomal protein S6 kinase beta [EC:2.7.11.1] | 0 | 0 |
| K04692 | signal transducer and activator of transcription 3 | 0 | 0 |
| K04696 | suppressor of cytokine signaling 3 | 0 | 0 |
| K04734 | NF-kappa-B inhibitor alpha | 0 | 0 |
| K04735 | transcription factor p65 | 0 | 0 |
| K05405 | interleukin 6 | 0 | 0 |
| K05695 | receptor-type tyrosine-protein phosphatase F [EC:3.1.3.48] | 0 | 0 |
| K05696 | tyrosine-protein phosphatase non-receptor type 1 [EC:3.1.3.48] | 0 | 0 |
| K05870 | cyclic AMP-responsive element-binding protein 1 | 0 | 0 |
| K06068 | novel protein kinase C delta type [EC:2.7.11.13] | 0 | 0 |
| K06259 | CD36 antigen | 0 | 0 |
| K06269 | serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] | 0 | 0 |
| K06276 | 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1] | 0 | 0 |
| K07187 | insulin receptor substrate 2 | 0 | 0 |
| K07189 | protein phosphatase 1 regulatory subunit 3A/B/C/D/E | 0 | 0 |
| K07191 | MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4 | 0 | 0 |
| K07197 | sterol regulatory element-binding transcription factor 1 | 0 | 0 |
| K07198 | 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31] | 0 | 0 |
| K07199 | 5'-AMP-activated protein kinase, regulatory beta subunit | 0 | 0 |
| K07200 | 5'-AMP-activated protein kinase, regulatory gamma subunit | 0 | 0 |
| K07201 | forkhead box protein O1 | 0 | 0 |
| K07202 | alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha | 0 | 0 |
| K07203 | serine/threonine-protein kinase mTOR [EC:2.7.11.1] | 0 | 0 |
| K07209 | inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10] | 0 | 0 |
| K07293 | tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48] | 0 | 0 |
| K07294 | peroxisome proliferator-activated receptor alpha | 0 | 0 |
| K07299 | MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1 | 0 | 0 |
| K07593 | MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2 | 0 | 0 |
| K08535 | liver X receptor beta | 0 | 0 |
| K08536 | liver X receptor alpha | 0 | 0 |
| K08745 | solute carrier family 27 (fatty acid transporter), member 1/4 [EC:6.2.1.-] | 0 | 0 |
| K08746 | solute carrier family 27 (fatty acid transporter), member 2 [EC:6.2.1.- 6.2.1.3] | 0 | 0 |
| K08748 | solute carrier family 27 (fatty acid transporter), member 5 [EC:6.2.1.7] | 0 | 0 |
| K08749 | solute carrier family 27 (fatty acid transporter), member 6 | 0 | 0 |
| K08765 | carnitine O-palmitoyltransferase 1, liver isoform [EC:2.3.1.21] | 0 | 0 |
| K08772 | solute carrier family 27 (fatty acid transporter), member 3 [EC:6.2.1.-] | 0 | 0 |
| K09047 | cyclic AMP-responsive element-binding protein 5 | 0 | 0 |
| K09048 | cyclic AMP-responsive element-binding protein 3 | 0 | 0 |
| K09113 | MAX-like protein X | 0 | 0 |
| K09667 | protein O-GlcNAc transferase [EC:2.4.1.255] | 0 | 0 |
| K09821 | angiotensinogen | 0 | 0 |
| K11533 | fatty acid synthase, bacteria type [EC:2.3.1.-] | 0 | 0 |
| K13242 | nitric-oxide synthase, endothelial [EC:1.14.13.39] | 0 | 0 |
| K14497 | protein phosphatase 2C [EC:3.1.3.16] | 0 | 0 |
| K15719 | protein O-GlcNAcase / histone acetyltransferase [EC:3.2.1.169 2.3.1.48] | 0 | 0 |
| K16172 | insulin receptor substrate 1 | 0 | 0 |
| K16333 | CREB-regulated transcription coactivator 2 | 0 | 0 |
| K17605 | serine/threonine-protein phosphatase 2A activator | 0 | 0 |
| K17902 | TBC1 domain family member 4 | 0 | 0 |
| K17962 | peroxisome proliferator-activated receptor gamma coactivator 1-beta | 0 | 0 |
| K18050 | novel protein kinase C epsilon type [EC:2.7.11.13] | 0 | 0 |
| K18052 | novel protein kinase C theta type [EC:2.7.11.13] | 0 | 0 |
| K18952 | atypical protein kinase C zeta type [EC:2.7.11.13] | 0 | 0 |
| K19518 | tribbles homolog 3 | 0 | 0 |
| K19523 | carnitine O-palmitoyltransferase 1, muscle isoform [EC:2.3.1.21] | 0 | 0 |
| K19662 | classical protein kinase C beta type [EC:2.7.11.13] | 0 | 0 |