Help to interpret the results
The page contains two contents:
General: this table lists the KO entries and their description specific to this pathway, and provides their frequencies in Proteus mirabilis HI4320 and in the whole dataset.
Profile + homologs: the distribution of the Kegg entries of Th17 cell differentiation Kegg pathway is displayed here. Given a Kegg entry and a genome, a red box indicates that one or more loci have been annotated with, while a green box indicates that no locus/loci has(have) been annotated with it, but it/they is/are part of an Orthologous group in which other members have been annotated with that Kegg entry, so it is likely that this copy(ies) also performs this Kegg function.
Check the composition of the Th17 cell differentiation pathway
| KO | Description | #in this genome | All occurrences |
|---|---|---|---|
| K01116 | phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11] | 0 | 0 |
| K02580 | nuclear factor NF-kappa-B p105 subunit | 0 | 0 |
| K02581 | NF-kappa-B inhibitor beta | 0 | 0 |
| K04079 | molecular chaperone HtpG | 1 | 7 |
| K04348 | serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16] | 0 | 0 |
| K04371 | mitogen-activated protein kinase 1/3 [EC:2.7.11.24] | 0 | 0 |
| K04379 | proto-oncogene protein c-fos | 0 | 0 |
| K04386 | interleukin 1 receptor type I | 0 | 0 |
| K04388 | TGF-beta receptor type-2 [EC:2.7.11.30] | 0 | 0 |
| K04440 | mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24] | 0 | 0 |
| K04441 | p38 MAP kinase [EC:2.7.11.24] | 0 | 0 |
| K04446 | nuclear factor of activated T-cells, cytoplasmic 1 | 0 | 0 |
| K04447 | Janus kinase 2 [EC:2.7.10.2] | 0 | 0 |
| K04448 | transcription factor AP-1 | 0 | 0 |
| K04467 | inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10] | 0 | 0 |
| K04500 | mothers against decapentaplegic homolog 2 | 0 | 0 |
| K04501 | mothers against decapentaplegic homolog 4 | 0 | 0 |
| K04519 | interleukin 1 beta | 0 | 0 |
| K04674 | TGF-beta receptor type-1 [EC:2.7.11.30] | 0 | 0 |
| K04687 | interferon gamma | 0 | 0 |
| K04692 | signal transducer and activator of transcription 3 | 0 | 0 |
| K04723 | interleukin 1 receptor accessory protein | 0 | 0 |
| K04734 | NF-kappa-B inhibitor alpha | 0 | 0 |
| K04735 | transcription factor p65 | 0 | 0 |
| K05055 | interleukin 6 receptor | 0 | 0 |
| K05060 | interleukin 6 signal transducer | 0 | 0 |
| K05063 | interleukin 12 receptor beta-1 | 0 | 0 |
| K05065 | interleukin 23 receptor | 0 | 0 |
| K05068 | interleukin 2 receptor alpha | 0 | 0 |
| K05069 | interleukin 2 receptor beta | 0 | 0 |
| K05070 | interleukin 2 receptor gamma | 0 | 0 |
| K05071 | interleukin 4 receptor | 0 | 0 |
| K05075 | interleukin 21 receptor | 0 | 0 |
| K05132 | interferon gamma receptor 1 | 0 | 0 |
| K05133 | interferon gamma receptor 2 | 0 | 0 |
| K05405 | interleukin 6 | 0 | 0 |
| K05426 | interleukin 23 subunit alpha | 0 | 0 |
| K05429 | interleukin 2 | 0 | 0 |
| K05430 | interleukin 4 | 0 | 0 |
| K05434 | interleukin 21 | 0 | 0 |
| K05445 | interleukin 22 | 0 | 0 |
| K05489 | interleukin 17A | 0 | 0 |
| K05494 | interleukin 17F | 0 | 0 |
| K05856 | lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2] | 0 | 0 |
| K05872 | NF-kappa-B inhibitor epsilon | 0 | 0 |
| K06268 | serine/threonine-protein phosphatase 2B regulatory subunit | 0 | 0 |
| K06450 | T-cell surface glycoprotein CD3 delta chain | 0 | 0 |
| K06451 | T-cell surface glycoprotein CD3 epsilon chain | 0 | 0 |
| K06452 | T-cell surface glycoprotein CD3 gamma chain | 0 | 0 |
| K06453 | CD3Z antigen, zeta polypeptide | 0 | 0 |
| K06454 | T-cell surface glycoprotein CD4 | 0 | 0 |
| K06752 | MHC class II antigen | 0 | 0 |
| K07203 | serine/threonine-protein kinase mTOR [EC:2.7.11.1] | 0 | 0 |
| K07209 | inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10] | 0 | 0 |
| K07210 | inhibitor of nuclear factor kappa-B kinase subunit gamma | 0 | 0 |
| K07360 | tyrosine-protein kinase ZAP-70 [EC:2.7.10.2] | 0 | 0 |
| K07362 | linker for activation of T cells family member 1 | 0 | 0 |
| K08268 | hypoxia-inducible factor 1 alpha | 0 | 0 |
| K08367 | runt-related transcription factor 1 | 0 | 0 |
| K08524 | retinoid X receptor alpha | 0 | 0 |
| K08525 | retinoid X receptor beta | 0 | 0 |
| K08526 | retinoid X receptor gamma | 0 | 0 |
| K08527 | retinoic acid receptor alpha | 0 | 0 |
| K08532 | RAR-related orphan receptor alpha | 0 | 0 |
| K08534 | RAR-related orphan receptor gamma | 0 | 0 |
| K09093 | aryl hydrocarbon receptor | 0 | 0 |
| K09445 | interferon regulatory factor 4 | 0 | 0 |
| K10163 | forkhead box P3 | 0 | 0 |
| K10166 | T-box protein 21 | 0 | 0 |
| K10784 | T cell receptor alpha chain V region | 0 | 0 |
| K10785 | T-cell receptor beta chain V region | 0 | 0 |
| K11217 | Janus kinase 1 [EC:2.7.10.2] | 0 | 0 |
| K11218 | Janus kinase 3 [EC:2.7.10.2] | 0 | 0 |
| K11219 | non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2] | 0 | 0 |
| K11220 | signal transducer and activator of transcription 1 | 0 | 0 |
| K11223 | signal transducer and activator of transcription 5A | 0 | 0 |
| K11224 | signal transducer and activator of transcription 5B | 0 | 0 |
| K11225 | signal transducer and activator of transcription 6 | 0 | 0 |
| K13375 | transforming growth factor beta-1 | 0 | 0 |
| K17332 | nuclear factor of activated T-cells, cytoplasmic 2 | 0 | 0 |
| K17333 | nuclear factor of activated T-cells, cytoplasmic 3 | 0 | 0 |
| K17895 | GATA-binding protein 3 | 0 | 0 |
| K18052 | novel protein kinase C theta type [EC:2.7.11.13] | 0 | 0 |
| K19598 | interleukin 27 receptor alpha | 0 | 0 |
| K22629 | interleukin 27 subunit alpha | 0 | 0 |
| K23605 | mothers against decapentaplegic homolog 3 | 0 | 0 |
| K24476 | interleukin 27 subunit beta | 0 | 0 |