Help to interpret the results
The page contains two contents:
General: this table lists the KO entries and their description specific to this pathway, and provides their frequencies in Morganella morganii S1 and in the whole dataset.
Profile + homologs: the distribution of the Kegg entries of Necroptosis Kegg pathway is displayed here. Given a Kegg entry and a genome, a red box indicates that one or more loci have been annotated with, while a green box indicates that no locus/loci has(have) been annotated with it, but it/they is/are part of an Orthologous group in which other members have been annotated with that Kegg entry, so it is likely that this copy(ies) also performs this Kegg function.
Check the composition of the Necroptosis pathway
| KO | Description | #in this genome | All occurrences |
|---|---|---|---|
| K00261 | glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3] | 0 | 0 |
| K00460 | arachidonate 15-lipoxygenase [EC:1.13.11.33] | 0 | 0 |
| K00522 | ferritin heavy chain [EC:1.16.3.2] | 0 | 0 |
| K00688 | glycogen phosphorylase [EC:2.4.1.1] | 0 | 0 |
| K01367 | calpain-1 [EC:3.4.22.52] | 0 | 0 |
| K01370 | caspase 1 [EC:3.4.22.36] | 0 | 0 |
| K01915 | glutamine synthetase [EC:6.3.1.2] | 1 | 7 |
| K02159 | apoptosis regulator BAX | 0 | 0 |
| K02161 | apoptosis regulator Bcl-2 | 0 | 0 |
| K02373 | FAS-associated death domain protein | 0 | 0 |
| K02861 | receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1] | 0 | 0 |
| K03156 | tumor necrosis factor superfamily, member 2 | 0 | 0 |
| K03158 | tumor necrosis factor receptor superfamily member 1A | 0 | 0 |
| K03171 | tumor necrosis factor receptor type 1-associated DEATH domain protein | 0 | 0 |
| K03173 | TNF receptor-associated factor 2 [EC:2.3.2.27] | 0 | 0 |
| K03767 | peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8] | 1 | 7 |
| K03853 | calpain-2 [EC:3.4.22.53] | 0 | 0 |
| K04079 | molecular chaperone HtpG | 1 | 7 |
| K04383 | interleukin 1 alpha | 0 | 0 |
| K04389 | tumor necrosis factor ligand superfamily member 6 | 0 | 0 |
| K04390 | tumor necrosis factor receptor superfamily member 6 | 0 | 0 |
| K04398 | caspase 8 [EC:3.4.22.61] | 0 | 0 |
| K04440 | mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24] | 0 | 0 |
| K04447 | Janus kinase 2 [EC:2.7.10.2] | 0 | 0 |
| K04515 | calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17] | 0 | 0 |
| K04519 | interleukin 1 beta | 0 | 0 |
| K04687 | interferon gamma | 0 | 0 |
| K04692 | signal transducer and activator of transcription 3 | 0 | 0 |
| K04693 | interferon regulatory factor 9 | 0 | 0 |
| K04721 | tumor necrosis factor ligand superfamily member 10 | 0 | 0 |
| K04722 | tumor necrosis factor receptor superfamily member 10A/B | 0 | 0 |
| K04724 | CASP8 and FADD-like apoptosis regulator | 0 | 0 |
| K04725 | E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27] | 0 | 0 |
| K04726 | BH3 interacting domain death agonist | 0 | 0 |
| K04727 | apoptosis-inducing factor 1 [EC:1.-.-.-] | 0 | 0 |
| K04982 | transient receptor potential cation channel subfamily M member 7 [EC:2.7.11.1] | 0 | 0 |
| K05130 | interferon receptor 1 | 0 | 0 |
| K05131 | interferon receptor 2 | 0 | 0 |
| K05132 | interferon gamma receptor 1 | 0 | 0 |
| K05133 | interferon gamma receptor 2 | 0 | 0 |
| K05401 | toll-like receptor 3 | 0 | 0 |
| K05409 | TRIF-related adaptor molecule | 0 | 0 |
| K05414 | interferon alpha | 0 | 0 |
| K05415 | interferon beta | 0 | 0 |
| K05842 | toll-like receptor adapter molecule 1 | 0 | 0 |
| K05862 | voltage-dependent anion channel protein 1 | 0 | 0 |
| K05863 | solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31 | 0 | 0 |
| K05864 | peptidyl-prolyl isomerase D [EC:5.2.1.8] | 0 | 0 |
| K08601 | ubiquitin carboxyl-terminal hydrolase CYLD [EC:3.4.19.12] | 0 | 0 |
| K08847 | receptor-interacting serine/threonine-protein kinase 3 [EC:2.7.11.1] | 0 | 0 |
| K08849 | mixed lineage kinase domain-like [EC:2.7.11.1] | 0 | 0 |
| K09849 | TNF receptor-associated factor 5 | 0 | 0 |
| K10160 | toll-like receptor 4 | 0 | 0 |
| K10630 | RanBP-type and C3HC4-type zinc finger-containing protein 1 [EC:2.3.2.31] | 0 | 0 |
| K10802 | high mobility group protein B1 | 0 | 0 |
| K11217 | Janus kinase 1 [EC:2.7.10.2] | 0 | 0 |
| K11218 | Janus kinase 3 [EC:2.7.10.2] | 0 | 0 |
| K11219 | non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2] | 0 | 0 |
| K11220 | signal transducer and activator of transcription 1 | 0 | 0 |
| K11221 | signal transducer and activator of transcription 2 | 0 | 0 |
| K11222 | signal transducer and activator of transcription 4 | 0 | 0 |
| K11223 | signal transducer and activator of transcription 5A | 0 | 0 |
| K11224 | signal transducer and activator of transcription 5B | 0 | 0 |
| K11225 | signal transducer and activator of transcription 6 | 0 | 0 |
| K11251 | histone H2A | 0 | 0 |
| K11859 | tumor necrosis factor, alpha-induced protein 3 [EC:3.4.19.12] | 0 | 0 |
| K11974 | E3 ubiquitin-protein ligase RNF31 [EC:2.3.2.31] | 0 | 0 |
| K12191 | charged multivesicular body protein 2A | 0 | 0 |
| K12192 | charged multivesicular body protein 2B | 0 | 0 |
| K12193 | charged multivesicular body protein 3 | 0 | 0 |
| K12194 | charged multivesicular body protein 4A/B | 0 | 0 |
| K12195 | charged multivesicular body protein 6 | 0 | 0 |
| K12196 | vacuolar protein-sorting-associated protein 4 | 0 | 0 |
| K12197 | charged multivesicular body protein 1 | 0 | 0 |
| K12198 | charged multivesicular body protein 5 | 0 | 0 |
| K12350 | sphingomyelin phosphodiesterase [EC:3.1.4.12] | 0 | 0 |
| K12799 | apoptosis-associated speck-like protein containing a CARD | 0 | 0 |
| K12800 | NACHT, LRR and PYD domains-containing protein 3 | 0 | 0 |
| K12965 | Z-DNA binding protein 1 | 0 | 0 |
| K12967 | interleukin 33 | 0 | 0 |
| K13625 | ferritin light chain | 0 | 0 |
| K14381 | sequestosome 1 | 0 | 0 |
| K15040 | voltage-dependent anion channel protein 2 | 0 | 0 |
| K15041 | voltage-dependent anion channel protein 3 | 0 | 0 |
| K15053 | charged multivesicular body protein 7 | 0 | 0 |
| K15637 | serine/threonine-protein phosphatase PGAM5 [EC:3.1.3.16] | 0 | 0 |
| K16060 | baculoviral IAP repeat-containing protein 2/3 | 0 | 0 |
| K16195 | eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1] | 0 | 0 |
| K16342 | cytosolic phospholipase A2 [EC:3.1.1.4] | 0 | 0 |
| K17065 | dynamin 1-like protein [EC:3.6.5.5] | 0 | 0 |
| K17595 | spermatogenesis-associated protein 2 | 0 | 0 |
| K20894 | shank-associated RH domain-interacting protein | 0 | 0 |
| K21421 | NADPH oxidase 2 [EC:1.-.-.-] | 0 | 0 |
| K21634 | ubiquitin carboxyl-terminal hydrolase 21 [EC:3.4.19.12] | 0 | 0 |
| K24070 | poly [ADP-ribose] polymerase 1 [EC:2.4.2.30] | 0 | 0 |
| K24782 | charged multivesicular body protein 4C | 0 | 0 |