Isoquinoline alkaloid biosynthesis


Help to interpret the results


The page contains two contents:
General: this table lists the KO entries and their description specific to this pathway, and provides their frequencies in Morganella morganii S5 and in the whole dataset.
Profile + homologs: the distribution of the Kegg entries of Isoquinoline alkaloid biosynthesis Kegg pathway is displayed here. Given a Kegg entry and a genome, a red box indicates that one or more loci have been annotated with, while a green box indicates that no locus/loci has(have) been annotated with it, but it/they is/are part of an Orthologous group in which other members have been annotated with that Kegg entry, so it is likely that this copy(ies) also performs this Kegg function.

Check the composition of the Isoquinoline alkaloid biosynthesis pathway


KO Description #in this genome All occurrences
K00274 monoamine oxidase [EC:1.4.3.4] 0 0
K00276 primary-amine oxidase [EC:1.4.3.21] 0 0
K00307 reticuline oxidase [EC:1.21.3.3] 0 0
K00422 polyphenol oxidase [EC:1.10.3.1] 0 0
K00501 tyrosine 3-monooxygenase [EC:1.14.16.2] 0 0
K00505 tyrosinase [EC:1.14.18.1] 0 0
K00811 aspartate aminotransferase, chloroplastic [EC:2.6.1.1] 0 0
K00812 aspartate aminotransferase [EC:2.6.1.1] 0 0
K00813 aspartate aminotransferase [EC:2.6.1.1] 1 7
K00815 tyrosine aminotransferase [EC:2.6.1.5] 0 0
K00832 aromatic-amino-acid transaminase [EC:2.6.1.57] 1 7
K00838 aromatic amino acid aminotransferase I / 2-aminoadipate transaminase [EC:2.6.1.57 2.6.1.39 2.6.1.27 2.6.1.5] 0 0
K01592 tyrosine decarboxylase [EC:4.1.1.25] 0 0
K01593 aromatic-L-amino-acid/L-tryptophan decarboxylase [EC:4.1.1.28 4.1.1.105] 0 0
K01742 thebaine synthase [EC:4.2.99.24] 0 0
K01828 neopinone isomerase [EC:5.3.3.24] 0 0
K03334 L-amino-acid oxidase [EC:1.4.3.2] 0 0
K03378 morphine 6-dehydrogenase [EC:1.1.1.218] 0 0
K11358 aspartate aminotransferase [EC:2.6.1.1] 0 0
K13371 aralkylamine dehydrogenase light chain [EC:1.4.9.2] 0 0
K13372 aralkylamine dehydrogenase heavy chain [EC:1.4.9.2] 0 0
K13382 (S)-norcoclaurine synthase [EC:4.2.1.78] 0 0
K13383 (RS)-norcoclaurine 6-O-methyltransferase [EC:2.1.1.128] 0 0
K13384 (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline N-methyltransferase [EC:2.1.1.115 2.1.1.140] 0 0
K13385 N-methylcoclaurine 3'-monooxygenase [EC:1.14.14.102] 0 0
K13386 3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase [EC:2.1.1.116] 0 0
K13387 berbamunine synthase [EC:1.14.19.66] 0 0
K13389 (S)-corytuberine synthase [EC:1.14.19.51] 0 0
K13390 (R,S)-reticuline 7-O-methyltransferase [EC:2.1.1.291] 0 0
K13391 salutaridine synthase [EC:1.14.19.67] 0 0
K13392 salutaridine reductase (NADPH) [EC:1.1.1.248] 0 0
K13393 salutaridinol 7-O-acetyltransferase [EC:2.3.1.150] 0 0
K13394 codeinone reductase [EC:1.1.1.247] 0 0
K13395 (S)-stylopine/(S)-canadine/(S)-nandinine synthase [EC:1.14.19.64 1.14.19.68 1.14.19.73] 0 0
K13396 (S)-tetrahydroprotoberberine N-methyltransferase [EC:2.1.1.122] 0 0
K13397 (S)-scoulerine 9-O-methyltransferase [EC:2.1.1.117] 0 0
K13398 columbamine O-methyltransferase [EC:2.1.1.118] 0 0
K14454 aspartate aminotransferase, cytoplasmic [EC:2.6.1.1] 0 0
K14455 aspartate aminotransferase, mitochondrial [EC:2.6.1.1] 0 0
K14975 codeine 3-O-demethylase [EC:1.14.11.32] 0 0
K14976 thebaine 6-O-demethylase [EC:1.14.11.31] 0 0
K15849 bifunctional aspartate aminotransferase and glutamate/aspartate-prephenate aminotransferase [EC:2.6.1.1 2.6.1.78 2.6.1.79] 0 0
K20621 (S)-N-methylcanadine 1-hydroxylase [EC:1.14.14.166] 0 0
K21070 (S)-cheilanthifoline synthase [EC:1.14.19.65] 0 0
K21208 noroxomaritidine synthase [EC:1.14.19.50 1.14.19.-] 0 0
K21311 norbelladine O-methyltransferase [EC:2.1.1.336] 0 0
K21580 reticuline N-methyltransferase [EC:2.1.1.337] 0 0
K21692 methyltetrahydroprotoberberine 14-monooxygenase [EC:1.14.14.97] 0 0
K21693 protopine 6-monooxygenase [EC:1.14.14.98] 0 0
K22088 norreticuline-7-O-methyltransferase [EC:2.1.1.-] 0 0
K22089 tetrahydroprotoberberine oxidase [EC:1.3.3.8] 0 0
K22090 noroxomaritidine/norcraugsodine reductase [EC:1.3.1.- 1.4.1.-] 0 0
K22091 O-methyltransferase [EC:2.1.1.-] 0 0
K22092 ipecoside beta-D-glucosidase [EC:3.2.1.220] 0 0
K22093 1,2-dehydroreticuline synthase/reductase [EC:1.14.19.54 1.5.1.27] 0 0
K22094 (S)-1-hydroxy-N-methylcanadine 13-hydroxylase [EC:1.14.14.163] 0 0
K22095 (13S,14R)-1,13-dihydroxy-N-methylcandine 13-O-acetyltransferase [EC:2.3.1.285] 0 0
K22096 (13S,14R)-13-O-acetyl-1-hydroxy-N-methylcanadine 8-hydroxylase [EC:1.14.14.167] 0 0
K22097 3-O-acetylpapaveroxine carboxylesterase [EC:3.1.1.105] 0 0
K22098 noscapine synthase [EC:1.1.1.415] 0 0
K22327 4-hydroxyphenylacetaldehyde synthase [EC:4.1.1.108] 0 0
K23157 3-O-acetyl-4'-O-demethylpapaveroxine 4'-O-methyltransferase subunit OMT2 [EC:2.1.1.352] 0 0
K23158 3-O-acetyl-4'-O-demethylpapaveroxine 4'-O-methyltransferase subunit OMT3 0 0